- Cardiovascular Health and Disease Prevention
- Cardiovascular Function and Risk Factors
- Hemodynamic Monitoring and Therapy
- Non-Invasive Vital Sign Monitoring
- Blood Pressure and Hypertension Studies
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Advanced Sensor and Energy Harvesting Materials
- Aortic aneurysm repair treatments
- Coronary Interventions and Diagnostics
- Advanced MRI Techniques and Applications
- Glaucoma and retinal disorders
- Conducting polymers and applications
- Scientific Measurement and Uncertainty Evaluation
- Corneal surgery and disorders
- Polymer composites and self-healing
- Retinal Imaging and Analysis
- Tactile and Sensory Interactions
- Mechanical Circulatory Support Devices
- Advanced X-ray and CT Imaging
- Statistical and numerical algorithms
- Cerebrovascular and Carotid Artery Diseases
- Muscle activation and electromyography studies
- Paraoxonase enzyme and polymorphisms
- Advanced X-ray Imaging Techniques
Stanford University
2017-2019
École Polytechnique Fédérale de Lausanne
2009-2016
Microsoft (United States)
2016
Tactile sensing is required for the dexterous manipulation of objects in robotic applications. In particular, ability to measure and distinguish real time normal shear forces crucial slip detection interaction with fragile objects. Here, we report a biomimetic soft electronic skin (e-skin) that composed an array capacitors capable measuring discriminating both tangential forces. It enabled by three-dimensional structure mimics interlocked dermis-epidermis interface human skin. Moreover,...
Abstract The long application life and stable performance of stretchable electronics have been putting forward requirements for both higher mechanical properties better self‐healing ability polymeric substrates. However, materials, simultaneously improving stretchability robustness is still challenging. Here, by incorporating sliding crosslinker (polyrotaxanes) hydrogen bonds into a polymer, highly self‐healable elastomer with good strength achieved. exhibits very high stretchability, such...
The method used for pulse transit time (PTT) estimation critically affects the accuracy and precision of regional wave velocity (PWV) measurements. Several methods PTT exist, often yielding substantially different PWV values. Since there is no analytic way to determine in vivo, these cannot be validated except by using silico or vitro models known We aimed validate compare most commonly "foot-to-foot" algorithms, namely, " diastole-minimum," "tangential," "maximum first derivative," second...
Abstract Electronics offering modularity in design and function, i.e., modular electronics have enabled a wide gamut of applications, such as promotion creativity, self‐assembling robots, customizable consumer electronics. In particular, there is recently fertile application domain within the rapidly growing needs wearable technologies. Toward this application, it proposed that stretchable, self‐healable, mechanically tough materials will enable highly desirable reconfigurable...
Cardiac output (CO) monitoring is essential for the optimal management of critically ill patients. Several mathematical methods have been proposed CO estimation based on pressure waveform analysis. Most them depend invasive recording blood and require repeated calibrations, they suffer from decreased accuracy under specific conditions. A new systolic volume balance (SVB) method, including a simpler empirical form (eSVB), was derived basic physical principles that govern flow and, in...
Left atrial (LA) dilatation is associated with a large variety of cardiac diseases. Current cardiovascular magnetic resonance (CMR) strategies to measure LA volumes are based on multi-breath-hold multi-slice acquisitions, which time-consuming and susceptible misregistration. To develop time-efficient single breath-hold 3D CMR acquisition reconstruction method precisely function. A highly accelerated compressed-sensing cine sequence (CS-cineCMR) was combined non-model-based high temporal...
We propose a new variational framework for the problem of reconstructing flow fields from noisy measurements. The formalism is based on regularizers penalizing singular values Jacobian field. Specifically, we rely nuclear norm. Our method invariant with respect to fundamental transformations and can be efficiently solved. conduct numerical experiments several phantom data report improved performance compared existing vectorial extensions total variation curl-divergence regularizations....
We introduce a novel variational framework for the regularized reconstruction of time-resolved volumetric flow fields. Our objective functional takes physical characteristics underlying into account in both spatial and temporal domains. For an efficient minimization functional, we apply proximal-splitting algorithm perform parallel computations. To demonstrate utility our method, first denoise simulated flow-field human aorta show that method outperforms spatial-only regularization terms...
Carotid-to-femoral pulse wave velocity (PWV) is the gold standard for assessment of aortic stiffness. It calculated by ratio transit time (PTT) between two arterial sites and distance them. The precision PTT estimation depends upon algorithm that determines characteristic points at foot waveforms. Different algorithms yield variable values thus affecting PWV subsequently its diagnostic prognostic accuracy. Our aim was to apply in vivo a new 'diastole-patching' investigate whether it improves...
Methods A highly accelerated prototype cine sequence with sparse sampling and Iterative Reconstruction (sCINE-IR) was used in phantoms patients to acquire 5 slices (2 long axis, LAX 3 short SAX) through the LA during a single breathhold yielding spatial/temporal resolution of 1.5mm/30ms (1.5T Aera, Siemens AG, Germany). The volumes were reconstructed from these using non-model based method (Bermano A, ACM trans Graph 2011). As reference patients, self-navigated high-resolution whole-heart 3D...
Vascular prostheses currently used in aortic replacement surgery do not have the same mechanical properties as human arteries. In vivo studies revealed that grafts augment heart load and alter blood pressure flow waveforms. A one-dimensional model of arterial tree was developed order to analyze different mechanisms by which placed ascending aorta (proximal) descending (distal) affect hemodynamics. Graft compliance were based on vitro tests. Predicted pressures at root compared for control,...
The monitoring of hemodynamic parameters is crucial for optimal patient management and treatment. However, established methods are often invasive possibly inapplicable to sensitive age groups. Novel, non-invasive techniques have the potential transform cardiovascular (CV) assessment, offering reduced hospitalization periods, lower infection risk decreased staff-to-patient ratio. Cardiac output (CO) provides valuable insight on global tissue perfusion. To overcome limitations traditional...