- Nanopore and Nanochannel Transport Studies
- Viral Infections and Immunology Research
- Carbon Nanotubes in Composites
- Graphene research and applications
- Effects and risks of endocrine disrupting chemicals
- Fullerene Chemistry and Applications
- SARS-CoV-2 and COVID-19 Research
- Advanced Photocatalysis Techniques
- Analytical chemistry methods development
- Adsorption and biosorption for pollutant removal
- Membrane Separation Technologies
- Inhalation and Respiratory Drug Delivery
- Pharmaceutical and Antibiotic Environmental Impacts
- Nanoparticles: synthesis and applications
- Ultrasound and Cavitation Phenomena
- Advanced Data Processing Techniques
- Soil Geostatistics and Mapping
- Water Systems and Optimization
- Covalent Organic Framework Applications
- Enhanced Oil Recovery Techniques
- Anesthesia and Sedative Agents
- RNA regulation and disease
- Polymer Nanocomposite Synthesis and Irradiation
- Membrane-based Ion Separation Techniques
- Grouting, Rheology, and Soil Mechanics
University of South Carolina
2013-2021
Clemson University
2016
North Carolina Agricultural and Technical State University
2011
The aggregation kinetics of nC60 and higher-order fullerene (HOF) clusters, i.e., nC70, nC76, nC84, was systematically studied under a wide range mono- (NaCl) divalent (CaCl2) electrolytes using time-resolved dynamic light scattering. Suwanee River Humic Acid (SRHA) also used to determine the effect natural macromolecules on nHOF aggregation. An increase in electrolyte concentration resulted electrical double-layer compression negatively charged nC60s nHOFs alike displayed classical...
Size-tunable stable aqueous fullerenes were prepared with different concentrations of biocompatible block-copolymer pluronic (PA) F-127, ranging from 0.001% to 1% (w/v). Size uniformity increased the increase in PA concentration, yielding optimum 58.8 ± 5.6 and 61.8 nm nC60s nC70s, respectively (0.10%w/v PA), as observed using a dynamic light scattering technique. Fullerene suspensions also manifested enhanced stability saline solution, Dulbecco's modified Eagle medium (DMEM), Roswell Park...
The nonstructural protein 1 (nsp1) of severe acute respiratory syndrome coronavirus and 2 is a critical viral that suppresses host gene expression by blocking the assembly ribosome on mRNAs. To understand mechanism inhibition expression, we sought to identify cellular proteins interact with nsp1. Using proximity-dependent biotinylation followed proteomic analyses biotinylated proteins, here captured multiple dynamic interactions nsp1 cell proteins. In addition ribosomal identified several...
PVP coatings on magnetic NPs are partially displaced in the presence of fulvic acid, which reduces crude oil adsorption onto magnetite.
Accurate information about contaminant plume migration in the subsurface plays an important role risk assessment and emergency response during site remediation. Rapid severe soil contamination can help to reduce extent of damage groundwater contamination. The use transport models, coupled with stochastic data assimilation schemes, provide accurate prediction enhance reliability area environmental In this study, a two-dimensional deterministic model is used simulate advective diffusive...
Molecular docking and Targeted Dynamics Simulations were conducted to elucidate binding properties of SARS-CoV-2 nonstructural protein 1 (nspl) onto the human ribosomal 40S complex. Nspl serves as a host shutoff factor by blocking ribosome assembly on mRNAs, thereby suppressing gene expression. Recently, cryo-electron microscope structure both 80S purified in presence nspl revealed C-terminal region mRNA site ribosome. This gives first insight into molecular mechanism nspl-mediated...