A5015156321- Radioactive element chemistry and processing
- Analytical chemistry methods development
- Extraction and Separation Processes
- Dental Research and COVID-19
- Caveolin-1 and cellular processes
- Problem and Project Based Learning
- Innovations in Medical Education
- Electrochemical Analysis and Applications
- Signaling Pathways in Disease
- Lipoproteins and Cardiovascular Health
- Augmented Reality Applications
- Analytical Chemistry and Sensors
- Mobile Learning in Education
- AI in cancer detection
- Chemical Synthesis and Characterization
- Anatomy and Medical Technology
- Protease and Inhibitor Mechanisms
- Educational Games and Gamification
- Innovative Teaching Methods
- Biomedical and Engineering Education
- Advanced Chemical Sensor Technologies
- Cell Adhesion Molecules Research
- Learning Styles and Cognitive Differences
- Nitric Oxide and Endothelin Effects
- Environmental Chemistry and Analysis
University of Alberta
2011-2025
American Dental Education Association
2023
General Services Administration
2023
John Wiley & Sons (United States)
2023
Children's Hospital of Philadelphia
2012
Pediatrics and Genetics
2009
St Mary's Hospital
2006
Imperial College London
2006
Ludwig Cancer Research
2004
Yale University
2004
Plasma high-density lipoprotein is commonly estimated by measuring the cholesterol remaining in plasma supernatant solutions after other lipoproteins, which contain apolipoprotein B, are precipitated with heparin and Mn2+. The method (method I) now use Lipid Research Clinics, Mn2+ at 46 mmol/liter final concentration, reasonably accurate, but precipitation sedimentation of lipoproteins than often incomplete. We evaluated two modifications I. In II, concentration was doubled; second...
Matrix metalloproteinase-2 (MMP-2) is best understood for its biological actions outside the cell. However, MMP-2 also localizes to intracellular compartments and cytosol where it has several substrates, including troponin I (TnI). Despite a growing list of cytosolic we currently do not know mechanism(s) that give rise equilibrium between secreted moieties. Therefore, explored how cells achieve unique distribution this protease. Our data show endogenous targets inefficiently endoplasmic...
Abstract A fast and efficient method has been developed for the extraction concentration of PCB from water. The uses porous polyurethane foam as absorption column which is eluted with acetone hexane G. C. analysis.
GPT-4o is an autoregressive omni model that accepts as input any combination of text, audio, image, and video, generates image outputs. It's trained end-to-end across vision, meaning all inputs outputs are processed by the same neural network. can respond to audio in little 232 milliseconds, with average 320 which similar human response time conversation. It matches GPT-4 Turbo performance on text English code, significant improvement non-English languages, while also being much faster 50\%...
Objectives: A growing number of health professional institutions around the world are embracing innovative technologies to increase student engagement, primarily improve clinical and simulated learning experiences. Didactic is an essential component dental medical curricula. However, limited research available regarding implementation technology-infused teaching in classroom settings. We developed self-paced interactive content using HTML5 Package (H5P) promote engagement a didactic course...
ABSTRACT Background Recent advancements in precision medicine and dentistry have necessitated genomic literacy healthcare professionals. Both the knowledge of genetics data primary biological databases are rapidly expanding beyond what is presented textbooks. Dental students often unfamiliar with growing field tools used to analyse interpret genetic information. Approach To improve among dental students, we incorporated ‘Bioinformatics for Dentistry’, a dental‐specific secondary database, as...
Abstract Purpose This study investigated the surface detail reproduction and dimensional stability of a vinyl polyether silicone (VPES) in comparison to vinylpolysiloxane (VPS) material as function prolonged storage for up 2 weeks. Materials Methods Heavy‐body VPES (EXA'lence TM Fast Set) VPS (Imprint 3 Quick Step) were compared. Forty impression ingots each made using stainless steel die described by ANSI/ADA specification No. 19. Twenty impressions disinfected immersion 2.5% buffered...
We previously reported a 50% reduction in cortical infarct volume following transient focal cerebral ischemia rats preconditioned 3 days earlier with spreading depression (CSD). The mechanism of the protective effect prior CSD remains unknown. Recent studies demonstrate reversal excitatory amino acid transporters (EAATs) to be principal cause for elevated extracellular glutamate levels during ischemia. present study measured preconditioning on (a) intraischemic and (b) regulation within...
Persistent arterial hypotension is a hallmark of sepsis and believed to be caused, at least in part, by excess nitric oxide (NO). NO can combine with superoxide produce peroxynitrite, which activates matrix metalloproteinases (MMPs). Whether MMP inhibition vivo protects against vascular hyporeactivity induced endotoxemia unknown. Male Sprague-Dawley rats were administered either bacterial lipopolysaccharide (LPS, 4 mg/kg ip) or vehicle (pyrogen-free water). Later (30 min), animals received...
Abstract Matrix metalloproteinase‐2 (MMP‐2) may play roles at intracellular and extracellular sites of the heart in ischaemia/reperfusion injury. Caveolins (Cav‐1, ‐2 ‐3) are lipid raft proteins which cell sig‐nalling. This study examined, using immunohistochemistry two photon confocal microscopy, if MMP‐2 caveolins co‐localize plasma membrane cardiac cells: cardiomyocytes (CM), fibroblasts (FB) capillary endothelial cells (CEC) left ventricle (LV) Cav‐1 +/+ −/− mouse heart. In LV...
Genes strictly regulate the development of teeth and their surrounding oral structures. Alteration gene regulation leads to tooth disorders developmental anomalies in tooth, oral, facial regions. With advancement sequencing technology, genomic data is rapidly increasing. However, large sets proteomic related dental are currently dispersed many primary databases literature, making it difficult for users navigate, extract, study, or analyze. We have curated scattered genetic on created a...
Total joint arthroplasty (TJA) patients often receive allogeneic blood transfusion. In this study we sought to create and validate a clinical prediction rule for transfusion in TJA using data that are easily available when scheduling the procedure. Logistic regression modeling was applied retrospective from all procedures performed Edmonton, Alberta 2000 (n = 1875). The area under receiver operating curve resulting model training validation sets 0.80 0.76 respectively. By assigning simple...