A5075682657- Mechanical Behavior of Composites
- Metallurgy and Material Forming
- Metal Forming Simulation Techniques
- Advanced ceramic materials synthesis
- Microtubule and mitosis dynamics
- Microstructure and Mechanical Properties of Steels
- Aluminum Alloys Composites Properties
- Composite Structure Analysis and Optimization
- Photosynthetic Processes and Mechanisms
- Material Properties and Applications
- Protist diversity and phylogeny
- Fiber-reinforced polymer composites
- Structural Analysis and Optimization
- Metal Alloys Wear and Properties
- Structural Behavior of Reinforced Concrete
- Advanced Electron Microscopy Techniques and Applications
- Microstructure and mechanical properties
- Structural Analysis of Composite Materials
- Genetic and Kidney Cyst Diseases
- Lipid Membrane Structure and Behavior
- Textile materials and evaluations
- Advanced materials and composites
- Structural Load-Bearing Analysis
- Innovative concrete reinforcement materials
- Fatigue and fracture mechanics
Paul Scherrer Institute
2016-2025
ETH Zurich
2012-2025
Nagoya University
2013-2023
Netherlands Aerospace Centre
1985-2020
National Cerebral and Cardiovascular Center
1995-2020
Shinshu University
2019
Materials Science & Engineering
2009-2017
Kyoto University
2015-2016
Denso (Japan)
2014
Nippon Steel (Japan)
1992-2014
The upper and lower bounds of elastic stiffness compliance constants woven fabric composites are derived, based upon a mosaic-like model as well the assumptions constant stress strain. An approximate analysis taking into account fiber undulation continuity also is conducted. Fiber leads to slight softening in-plane does not affect stretching/bending coupling constants. A transverse shear deformation adopted modified examine one-dimensional bending response composites. results two-dimensional...
The recent status of Japan's government-driven project to establish carbon fiber reinforced thermoplastic composites (CFRTP) technology for automotive applications conducted in the National Composites Center (NCC) Japan is introduced first. baseline discontinuous (C-LFT-D: – long thermoplastic-direct) using press compaction. All components target car chassis made aluminum alloy are replaced by C-LFT-D and a 10% weight reduction with same rigidity has been verified. basic physics length...
Basic geometrical and material parameters are identified to characterize the structure of hybrid fabrics. Analysis elastic behavior is made based upon a mosaic model fabric composite can be regarded as an assemblage assymetrical crossply laminates. Upper lower bounds properties have been obtained results compare very favorably with experiments. The influence on has demonstrated especially for bending-stretching coupling effect. Essential considerations design also discussed.
Understanding the molecular architecture of flagellum is crucial to elucidate bending mechanism produced by this complex organelle. The current known structure has not yet been fully correlated with composition and localization flagellar components. Using cryoelectron tomography subtomogram averaging while distinguishing each one nine outer doublet microtubules, we systematically collected reconstructed three-dimensional structures in different regions Chlamydomonas flagellum. We visualized...
Bax and Bid are pro-apoptotic members of the Bcl-2 protein family. Upon cleavage by caspase-8, activates Bax. Activated inserts into mitochondrial outer membrane forming oligomers which lead to poration, release cytochrome c, apoptosis. The detailed mechanism activation topology composition still under debate. Here molecular details oligomerization were obtained application several biophysical techniques, including atomic force microscopy, cryoelectron particularly electron paramagnetic...
Radial spokes (RSs) are ubiquitous components in the 9 + 2 axoneme thought to be mechanochemical transducers involved local control of dynein-driven microtubule sliding. They composed >23 polypeptides, whose interactions and placement must deciphered understand RS function. In this paper, we show detailed three-dimensional (3D) structure situ Chlamydomonas reinhardtii flagella Tetrahymena thermophila cilia that obtained using cryoelectron tomography (cryo-ET). We clarify similarities...
The inner dynein arm regulates axonemal bending motion in eukaryotes. We used cryo-electron tomography to reconstruct the three-dimensional structure of arms from Chlamydomonas reinhardtii. All eight different heavy chains were identified one 96-nm periodic repeat, as expected previous biochemical studies. Based on mutants, we positions AAA rings and N-terminal tails all chains. f dimer is located close surface A-microtubule, whereas other six chain are roughly colinear at a larger distance...
This paper examines the non-linear elastic behavior of fabric composites. Three types non linearity including shear deformation fill threads, extensional pure matrix regions and transverse cracking warp have been taken into considerations. The constitutive relation developed by Hahn Tsai is adopted in this analysis fiber undulation bridging models Ishikawa Chou are also applied. Results for a glass 8 harness satin/polyimide composite compares remarkably well with experimental stress-strain...
Although the widely shared "9 + 2" structure of axonemes is thought to be highly symmetrical, show asymmetrical bending during planar and conical motion. In this study, using electron cryotomography single particle averaging, we demonstrate an molecular arrangement proteins binding nine microtubule doublets in Chlamydomonas reinhardtii flagella. The eight inner arm dynein heavy chains regulate determine flagellar waveform. Among these, one chain (dynein c) missing on doublet (this also lacks...
Photosystem II (PSII) is a multiprotein complex that splits water and initiates electron transfer in photosynthesis. The central part of PSII, the PSII core, surrounded by light-harvesting proteins (LHCIIs). In higher plants, two or three LHCII trimers are seen on each side core whereas only one corresponding positions Chlamydomonas reinhardtii, probably due to absence CP24, minor monomeric LHCII. Here, we re-examined supramolecular organization C. reinhardtii PSII-LHCII supercomplex...
<i>Escherichia coli</i> ClpA and ClpX are ATP-dependent protein unfoldases that each interact with the protease, ClpP, to promote specific degradation. We have used limited proteolysis deletion analysis probe conformations of their interactions ClpP substrates. ATPγS binding stabilized such cleavage by lysylendopeptidase C occurred at only two sites. Both proteins were cleaved within in a loop preceding an α-helix-rich C-terminal domain. Although varies size composition Clp ATPases, around...
This paper examines the in-plane thermal expansion coefficients and bend ing of fabric composites. Three physical models have been adopted. The "mosaic model" provides a simple means for estimating these properties. one-dimensional "fiber undulation two-dimensional "bridging are suitable in particular analyzing thermomechanical behavior plain weave satin composites, respectively. experimental results on 5-harness composite agree well with theory.
Microtubules are constructed from alpha- and beta-tubulin heterodimers that arranged into protofilaments. Most commonly there 13 or 14 A series of structural investigations using both electron microscopy x-ray diffraction have indicated two potential lattices (A B) in which the tubulin subunits can be arranged. Electron has shown kinesin heads, bind only to beta-tubulin, follow a helical path with 12-nm pitch repeat every 8-nm axially, implying primarily B-type lattice. However, these...
Type 1 pili from uropathogenic Escherichia coli are a prototype of adhesive surface organelles assembled and secreted by the conserved chaperone/usher pathway. We reconstituted type pilus biogenesis purified proteins. The usher FimD acted as catalyst to accelerate ordered assembly protein subunits independently cellular energy. Its activity was highly dependent on adhesin subunit FimH, which triggered conversion into high-efficiency catalyst. Furthermore, simple kinetic model adequately...