A5059938712- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Myasthenia Gravis and Thymoma
- T-cell and Retrovirus Studies
- Botulinum Toxin and Related Neurological Disorders
- Immunotherapy and Immune Responses
- Parkinson's Disease and Spinal Disorders
- Restless Legs Syndrome Research
- Muscle activation and electromyography studies
- Systemic Sclerosis and Related Diseases
- Peripheral Nerve Disorders
- Electroconvulsive Therapy Studies
- Neuroscience and Neural Engineering
- Family Support in Illness
- Vascular Malformations and Hemangiomas
- Autoimmune and Inflammatory Disorders Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Radiopharmaceutical Chemistry and Applications
- Soft tissue tumor case studies
- Nuclear Receptors and Signaling
- SARS-CoV-2 and COVID-19 Research
- Cytokine Signaling Pathways and Interactions
- Muscle and Compartmental Disorders
King Saud University
2014-2025
King Saud Medical City
2021-2024
King Fahd Medical City
2021
King Khalid University Hospital
2015
University of British Columbia Hospital
2015
Toronto General Hospital
2014
University of Toronto
2014
University of British Columbia
2013
Multiple sclerosis (MS) is an inflammatory disease associated with adverse effects: including depression, anxiety, fatigue, which may affect physical activity and the quality of life (QoL) among patients MS (pwMS).This study aims to assess prevalence fatigue pwMS who have no disability in Saudi Arabia, demonstrate any correlation between these factors as well QoL.A cross-sectional was conducted Neuroimmunology outpatient clinics King Fahad Medical City (KFMC) Saud University (KSUMC) Riyadh...
Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are distinct demyelinating diseases of the central nervous system, each characterized by unique patterns motor, sensory, visual dysfunction. While MS typically affects brain spinal cord, NMOSD predominantly targets optic nerves cord. This study aims to elucidate morphometric differences between focusing on gray matter volume changes in specific regions. We also examined if temporal follow-up MRI differentiate two...
In conventional non-quantitative magnetic resonance imaging, image contrast is consistent within images, but absolute intensity can vary arbitrarily between scans. For quantitative analysis of data, images are typically normalized to a reference. The most convenient reference tissue that always present in the image, and unlikely be affected by pathological processes. multiple sclerosis neuroimaging, both white gray matter affected, so normalization techniques depend on brain may introduce...
There are varying reports on whether monoclonal gammopathy of undetermined significance-associated neuropathy (MGUSN) patients distinguishable from those with chronic inflammatory demyelinating polyneuropathy (CIDP) and specific MGUSN subclasses associated clinical phenotypes.We performed a retrospective chart review (n = 56) CIDP 67) patients. Data extracted included: demographics, neurological examination, nerve conduction studies (NCS) at baseline last visit. Clinical status was rated as...
The advent of new disease-modifying therapies (DMTs), such as monoclonal antibodies (mAbs), resulted in significant changes the treatment guidelines for Multiple sclerosis (MS) and improvement clinical outcomes. However, mAbs, rituximab, natalizumab, ocrelizumab, are expensive with variable effectiveness rates. Thus, present study aimed to compare direct medical cost consequences (e.g., relapse, disability progression, MRI lesions) between rituximab natalizumab managing relapsing-remitting...
Objectives This study assessed the prevalence of restless leg syndrome (RLS) among patients with multiple sclerosis (pwMS) and association between RLS MS disease duration, sleep disturbance, daytime fatigue. Methods In this cross-sectional study, we interviewed 123 via phone calls using preset questionnaires containing International Restless Legs Syndrome Study Group (IRLSSG) diagnostic criteria, Pittsburgh Sleep Quality Index (PSQI), Fatigue Severity Scale (FSS) criteria validated in both...
Conversion disorder (CD) is a neurological symptom that not related to any medical or disease. Symptoms can range from sensory complaints loss of consciousness. Psychological stressors such as surgery and anesthesia are considered precipitating factors. Early diagnosis crucial prevent unnecessary interventions. Here, we report case patient who developed CD upon emergence general anesthesia.
Focal myositis secondary to an intramuscular vascular malformation has rarely been reported in the literature. We describe a 21-year-old woman presenting with left thigh pain. Imaging of muscles showed and muscle biopsy demonstrated focal changes diagnosed initially as myositis. Ischaemia is thought be responsible mechanism.
BackgroundThe outbreak of coronavirus disease 2019 (COVID-19) has rapidly spread and developed as a pandemic threatening global health. Patients with multiple sclerosis (MS)–an autoimmune demyelinating inflammatory the central nervous system (CNS)–are predominantly treated immunomodulatory/immunosuppressive disease-modifying therapies (DMTs), which can increase risk infection. Therefore, there is concern that these patients may have higher COVID-19. In response to growing concerns...
<h3>Objectives:</h3> To determine nerve conduction studies (NCS) reference data for motor nerves and F-waves in the upper lower limbs of healthy subjects Saudi Arabia. <h3>Methods:</h3> This is a cross-sectional study conducted between May 2015 June 2019. Healthy without neurological or systemic diseases were recruited. Motor NCS performed following standard protocol. Pearson correlations employed parameters age, gender, height, weight, body mass index. Reference generated using percentile...
The very fact that multiple sclerosis (MS) is incurable and necessitates life-long care makes it one of the most burdensome illnesses. aim this study was to compare cost-effectiveness orally administered medications (e.g., fingolimod, dimethyl fumarate, teriflunomide), interferon (IFN)-based therapy, monoclonal antibodies (MABs) natalizumab rituximab) in management relapsing-remitting (RRMS) Saudi Arabia using real-world data. This a retrospective cohort which patients with RRMS aged ≥18...
<b><i>Introduction:</i></b> There are a number of well-established risk factors for multiple sclerosis (MS). Other factors, however, showed conflicting or inconsistent results. Here, we examine some that unique to more practiced in Saudi Arabia (SA) and the Arab region such as waterpipe tobacco smoking (WTS), face veiling, raw milk (RM) camel (CM) consumption, tuberculosis (TB) infection addition other traditional factors....
A 41‐year‐old human T ‐lymphotropic virus type 1‐positive woman developed a syndrome with upper and lower motor neuron signs sometime after bilateral vertebral artery dissections. Over 2 years, she progressive myelopathy affecting predominantly the system. She had picture of ‘person in barrel’ died from complications. At autopsy, spinal cord revealed inflammatory infiltrates extensive gliosis involving mainly anterior horns. The arterial dissections may have permitted entry infected...
Multiple sclerosis (MS) is an inflammatory chronic disease that characterized by increased prevalence of adverse mental health outcomes in patients with MS (pwMS). The main aim this study to investigate the factors depression and anxiety pwMS Kingdom Saudi Arabia (KSA).This a cross-sectional conducted KSA during period from March June 2020. Participants were recruited Neuroimmunology clinics King Fahad Medical City (KFMC) Saud University medical city (KSUMC)in Riyadh City, KSA. Hospital...
<h3>Objectives:</h3> To estimate reference data for the commonly performed sensory nerve conduction studies (NCS) using a cohort of healthy subjects from Saudi Arabia <h3>Methods:</h3> This is cross-sectional study conducted between May 2015, and June 2019. Sensory action potential (SNAP) amplitude, velocity (CV), peak latency (PL) were recorded. Associations these parameters covariates (age, sex, height, weight, body mass index) tested with Pearson correlations. Reference then derived...
Multiple sclerosis (MS) is an inflammatory neurological illness common in young adults. The prevalence and incidence of MS are regionally globally increasing. Recent data from Saudi Arabia (SA) estimate the to be 40.40 cases per 100,000 population, 61.95 population for nationals. With increasing availability treatment options, new challenges selection approaches have emerged. There a clear need national guidelines standardize practice, guide personalization decisions, contain costs. A...