Relevance. Despite the widespread introduction of organ-preserving operations into urological practice, number radical nephrectomies has continued to increase. The results modern research show that initial stages diseases remaining kidney are already formed at earliest possible time after nephrectomy; therefore, adequate management postoperative period is a key factor in prevention single kidney. However, this approach should be based on detailed understanding mechanisms adaptive...

Background: One of the most important problems in medicine today is prevention chronic kidney disease development and progression patients who underwent radical nephrectomy. Surgical removal one initiates adaptive functional morphological restructuring other one. Changes condition remaining have been sufficiently detailed, whereas systemic metabolic disorders induced by surgical stress, which occur during remodeling parenchyma kidney, remain overlooked. Both local processes recovery,...

This article describes a clinical case of 28-year-old woman with long history chronic anemia (observed since 2017), hepatosplenomegaly, mesenteric lymphadenopathy, and proteinuria, initially diagnosed as tubulointerstitial nephritis CKD Stage 2. In April 2024, the patient was hospitalized to clarify diagnosis: series laboratory instrumental studies were conducted, including nephrobiopsy using standard methods, which did not reveal amyloid deposits. November based on re-evaluation previously...

Introduction. Injury to the testicular artery during microsurgical subinguinal varicocelectomy (MSV) results in atrophy 20 – 40% of cases. The use techniques that improve visualization could increase efficacy and safety MSV. Objective. To evaluate effect intraoperative Doppler control (IDC) on outcomes varicocelectomy. Materials & methods. Retrospective cohort study. study included 101 patients with clinical left-sided varicocele who underwent surgical treatment at «Mother Child...

In the review article, based on results of modern clinical and experimental studies, gender age-related features anatomy, physiology pathophysiology lower urinary tract are considered. The structure functioning urothelium, myothelium, neurothelium endothelium in men women described detail. A separate section is devoted to peculiarities hormonal regulation tract, depending age.

BACKGROUND: Bladder outlet obstruction caused by prostatic hyperplasia eventually leads to detrusor working hypertrophy, and its development is impossible without synchronous remodeling of vascular bed. Taking into account the age-associated nature disease, bladder transformation occurs following involutive structural changes both organ system due natural aging. To date, morphological features compensatory reactions bed, taking background age-related in wall, not fully disclosed.
 AIM:...

BACKGROUND: Recurrent cystitis is a common form of urinary tract infections. In the treatment this disease antibacterial drugs are usually used. At same time, there plant components that can be worthy substitute for antibiotic therapy.
 AIM: To evaluate efficacy and safety biologically active complex Cystalis, containing D-mannose, grape seed extract bearberry extract, in prevention recurrent women.
 MATERIALS AND METHODS: The study included 60 women with cystitis. All patients...

In this study an attempt was made to determine some reasons that prompted the urologist make a choice in favor of particular drug or combination from wide variety available drugs. The prescribing habits and subjective evaluation efficiency safety drugs for treatment lower urinary tract symptoms/benign prostatic hyperplasia by urologists Russia analyzed.a prospective multicenter epidemiological "LUTS/BPH - who treats?" carried out 12 centers using data obtained May 1 July 31, 2018 with...

BACKGROUND: Intraperitoneal damage to the bladder in pediatric population is a rare phenomenon. Publications describe small series of observations, generalizing studies are isolated. There no uniform diagnostic algorithms and tactics patient management, large number tactical errors.
 AIM: The aim this study evaluate possibilities laparoscopy diagnosis treatment patients under 18 years age with intraperitoneal injuries.
 MATERIALS AND METHODS: work was based on results 16...

Ceftriaxone-induced urolithiasis is a rare form of in childhood and accompanied even less often by postrenal (obstructive) acute kidney injury. Its development against the background surgical abdominal disease, for which antibacterial therapy being performed, seems difficult both from point view diagnosis treatment. A case treatment appendicular peritonitis complicated severe obstructive injury, was stopped minimally invasive methods with subsequent resolution obstruction, presented.

Relevance. Leukoplakia of the bladder is a rare disease, particularly in children. Most studies are based on individual clinical cases, and there few descriptions disease pediatric practice. Data etiology, prevalence, diagnosis, treatment contradictory adult patients. Materials methods. This article describes case leukoplakia childhood. Results. A diagnosis 14-year-old patient with presented. The was confirmed by cystoscopy biopsy affected area, after which transurethral resection performed....

Chronic kidney disease is becoming one of the leading causes death globally. Anemia, a common complication in chronic disease, not only diminishes patients’ life quality but also increases risk heart-related problems. The use recombinant human erythropoietin has revolutionized treatment anemia patients. By reaching desired levels hemoglobin with erythropoietin, patients experience significant improvements and decrease rates. Epoetin beta among various erythropoiesis stimulating agents...

IgM nephropathy, although a rare and controversial disease, attracts the attention of both morphologists clinicians. The issues etiopathogenesis, epidemiology treatment this pathology are currently insufficiently studied. A variety morphological manifestations under light microscopy make immunofluorescence examination crucial for diagnosis. Although nephropathy shares clinical features with minimal change disease focal segmental glomerulosclerosis, it has its own characteristics that not all...

Intraperitoneal traumatic perforations of the bladder any origin (e.g., external trauma, iatrogenic injuries) and spontaneous ruptures are conditions that, according to canons surgery, require emergency surgical intervention by one or another access. However, some studies have indicated possibility conservative management such patients — both adults children. A review publications describing results treatment with intraperitoneal was performed. Overall, 2,679 related were found in available...

The main physiological functions of globulin that binds sex hormones (SHBG) in the male body are transport steroids hydrophilic blood and creation a buffer system smooths out fluctuations concentration free testosterone. In addition, hormone binding can limit biological activity by reducing fraction hormone, but only when hypothalamicpituitary-testicular axis is non-functioning or inadequately functioning. If negative feedback mechanism works correctly, SHBG will determine level total...

Introduction . Effective treatment of renal anaemia is achieved due to the use erythropoietin-stimulating agents, which not only increase haemoglobin levels, but also significantly improve prognosis for cardiovascular diseases in patients on haemodialysis. Aim To evaluate safety and tolerability Russian recombinant human erythropoietin beta (Epostim®) intended intravenous administration maintain stable levels with chronic programmed Materials methods A retrospective study included 67...

The features of implantation a testicular prosthesis are insufficiently covered in modern literature. We present clinical observation implant replacement 56-year-old patient dissatisfied with the results primary implantation, discussion main causes dissatisfaction and ways to overcome them. Keywords: prosthetics, reimplantation prosthesis.

Relevance . Chronic abacterial prostatitis (CAP) of a non-inflammatory nature remains complex disease in terms proven etiological factors and pathogenetic mechanisms. Recent studies define it as nosology based on homeostasis disorders with damaging effects directed towards the prostate. Pathogenetically, this is cytokine aseptic inflammation lipid peroxidation, which occurs under conditions compromised antioxidant protection. Objective — to study status experimental reproduction CAP models....

A case of a rare combined defect - penoscortical transposition and scrotal hypospadias is presented. two-stage correction was performed, the second stage with penile transposition, resulting in good functional cosmetic results.

Представлен случай травматической ампутации головки пениса проксимальнее венечной борозды у ребёнка 5 лет при выполнении «ритуального обрезания» вне медицинского учреждения. В ранние сроки после травмы выполнена микрохирургическая реимплантация с хорошими ближайшими результатами.

Introduction. An age-associated increase in serum levels of sex hormone binding globulin (SHBG) is considered to be one the factors leading development male hypogonadism. Aim study: study relationship between concentration hormone-binding blood and age man, level total free testosterone. Materials methods. A single-center retrospective cross-sectional was conducted. The results laboratory tests 162 patients aged from 18 56 years (median – 34 years) were analyzed. testosterone determined by...

Current review is devoted to testicular prostheses. The authors have been studied the experience of prostheses usability from 1940 present. study shows some information adverse effect and implants tolerability. crucial point paper a future prospects implantation.

Aim of study. To evaluate the effectiveness closed manual detorsion in case testicular torsion children different age groups. Materials and methods. Manual was carried out according to classical technique (Yudin Ya.B. et al., 1987) by 79 patients with a at from neonatal period 18 years. A comparative analysis depending on various factors (the patient, duration ischemia, presence secondary hydrocele) performed. Results. The depended ischemia before manipulation all ages. is more pronounced...

Bladder concretions are one of the most frequent and difficult to correct complications bladder exstrophy. The significant proportion struvites in structure often creates an erroneous opinion about size latter makes it choose tactics. A case staged treatment exstrophy complicated by formation a concretion against background current active inflammatory process is presented. Contact cystolithotripsy preferred least traumatic method getting rid any size. In anatomical closure urethra, access...

BACKGROUND: Satisfaction with the results is a complex and poorly studied aspect of testicular prosthetics, which currently has no comprehensive consecration in literature. There are works that based on view problem, from subjective analysis local physical characteristics implant itself aesthetic perception one’s body to assessing impact prosthetics patient’s sex life socialization. AIM: The aim this study evaluate using an original questionnaire reflecting satisfaction implant, sexual...