A5028175402- Neuroendocrine regulation and behavior
- Hypothalamic control of reproductive hormones
- Neurotransmitter Receptor Influence on Behavior
- Memory and Neural Mechanisms
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Sexual function and dysfunction studies
- Evolutionary Psychology and Human Behavior
- Animal Behavior and Reproduction
- Tryptophan and brain disorders
- Ovarian function and disorders
- Hormonal and reproductive studies
- Plant and animal studies
- Neuropeptides and Animal Physiology
- Treatment of Major Depression
- Estrogen and related hormone effects
- Toxic Organic Pollutants Impact
- Anesthesia and Neurotoxicity Research
- Nicotinic Acetylcholine Receptors Study
- Diet and metabolism studies
- Photoreceptor and optogenetics research
- Menopause: Health Impacts and Treatments
- Epilepsy research and treatment
- Cannabis and Cannabinoid Research
- Franchising Strategies and Performance
Southwestern University
2015-2024
Dartmouth College
2002-2006
University of Vermont
1998-2002
McGill University
1997
The present study examined the effects of bilateral intra-amygdaloid infusions D2 receptor antagonist, eticlopride, on acquisition and expression Pavlovian fear conditioning as measured by freezing to acoustic background contextual stimuli in rat. Infusions eticlopride before or both retention testing significantly attenuated conditioned tone presentations during test 24 hr later. No effects, however, were observed that emerged acquisition. Furthermore, these not attributable state-dependent...
Three conditioned suppression experiments with rats examined the role of hippocampus in 2 effects context after extinction. Reinstatement is context-specific recovery fear to an extinguished stimulus (CS) that occurs following independent presentations unconditioned (US), Renewal when CS presented which it was conditioned, extinction a different context. Results indicated neurotoxic lesions hippocampus, performed before conditioning, abolished reinstatement, depends on context-US...
The effects of lesions to the hippocampal system on acquisition three different configural tasks by rats were tested. Lesions either hippocampus (kainic acid/colchicine) or fornix-fimbria (radiofrequency current) made before training. After recovery from surgery, trained discriminate between simple and compound-configural cues that signaled availability nonavailability food when a bar was pressed. When positive present, one pellet could be earned pressing lever after variable time had...
Female rats show a distinct attraction for males. This remains consistent without the necessity physical presence of male. However, identity olfactory cues contributing to in unknown. Rat urine contains copious amounts major urinary proteins (MUPs). Here, we investigated hypothesis that MUPs mediate sexual attractiveness rats. We first demonstrated member male dyad receiving greater copulatory opportunities competitive mate choice tests excrete MUPs. Furthermore, amount positively correlated...
Abstract Background GnRH agonists have been used to halt the development of puberty in children with precocious since 1980s. Recently, drugs like Lupron Depot ® (leuprolide acetate), suppress pubertal progression adolescents who are questioning their gender identity. However, few preclinical studies conducted investigate potential effects using this context. Methods The present study tested daily leuprolide treatment (50 µg/kg, postnatal day (PD) 25–50) on onset female (i.e., vaginal...
Methamphetamine (METH) is a highly addictive psychostimulant that has been shown to produce neurotoxicity. increases the release of dopamine by reversing direction monoamine transporter proteins, leading formation reactive oxygen species in brain. In this study, we examined effect METH on DNA damage vivo using single cell gel electrophoresis assay (comet assay) under two different conditions. Rats treated with multiple doses (10 mg/kg × 4) showed significant levels nucleus accumbens and...
The assessment of sexual behavior in male rats with the aim unraveling underlying neurobiological mechanisms has recent decades been reduced to annotation mounts, intromissions and ejaculations. To provide a better understanding structure patterns copulation, it is necessary extend tailor analysis natural organization rat copulation. This will lead formulation hypotheses about underpinnings behavior. Mounts are naturally organized mount bouts consisting one or more copulatory behaviors...
Histamine is an inflammatory mediator present in mast cells, which are abundant the wall of gallbladder. We examined electrical properties gallbladder smooth muscle and nerve associated with histamine-induced changes tone. Recordings were made from neurons, responses to histamine receptor subtype-specific compounds tested. application intact produced a concentration-dependent membrane depolarization increased excitability. In presence H 2 antagonist ranitidine, response was potentiated....