A5089114899- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Reproductive tract infections research
- Essential Oils and Antimicrobial Activity
- Mycotoxins in Agriculture and Food
- Climate Change and Health Impacts
- Oral microbiology and periodontitis research
- Health disparities and outcomes
- Cervical Cancer and HPV Research
- Nosocomial Infections in ICU
- Pneumocystis jirovecii pneumonia detection and treatment
- Infections and bacterial resistance
- Intramuscular injections and effects
- Bacterial biofilms and quorum sensing
- Clostridium difficile and Clostridium perfringens research
- Menstrual Health and Disorders
- Medical and Biological Ozone Research
- Biochemical effects in animals
- Intensive Care Unit Cognitive Disorders
- Infection Control in Healthcare
- Oral health in cancer treatment
- Medicinal Plant Research
- Moringa oleifera research and applications
- Antimicrobial agents and applications
- Coenzyme Q10 studies and effects
Birjand University of Medical Sciences
2020-2024
Tarbiat Modares University
2016-2019
Qom University of Medical Science and Health Services
2015
Background and Objectives: Vulvovaginal candidiasis (VVC) is a mucous membrane infection, with an increased rate of antifungal resistance Candida species. In this study, the in vitro efficacy farnesol alone or combination traditional antifungals was assessed against resistant strains recovered from women VVC. Materials Methods: Eighty isolates were identified by multiplex polymerase chain reaction (PCR), susceptibility to amphotericin B (AMB), fluconazole (FLU), itraconazole (ITZ),...
The evolution of drug resistance Candida species to conventional antifungal agents has been a major medical challenge worldwide; attempt use the potential with appropriate therapy efficacy and minimum effects is considerably growing. This study was conducted evaluate nanogel as nanocarrier for pharmaceutical application farnesol. nanogels were synthetized using alginate (AL) chitosan (CS) polymers containing 300 µM farnesol in nano-range 42-70 nm size. In vitro release studies indicated that...
Diet has the potential to decrease oxidative stress and inflammation this may be beneficial in several diseases. This study investigated association between food quality score (FQS) with antioxidant inflammatory properties 171 apparently healthy young women. cross-sectional was conducted using a validated frequency questionnaire determine dietary intake of participants. FQS calculated by summing all scores obtained from unhealthy groups. The total capacity free radical scavenging activity...
Some genes may be associated with Candida albicans resistance to azoles. Pir1 gene is described as responsible induce in C. albicans.The current study aimed find the relationship between fluconazole and protein (Pir1p) overexpression females recurrent vaginitis requiring longer therapy.A total of 52l vaginal samples were obtained from vaginitis. The azole susceptibility phenotype was determined according Clinical Laboratory for Standards Institute (CLSI) protocol disk diffusion method...
Background: Adhesion and biofilm formation are two important steps in Candida pathogenesis. The aim of the current study was to investigate presence bcr1 gene albicans (C. ) isolates from women with vaginal candidiasis its impact on formation. Methods: We used 50 clinical which confirmed C. by PCR-RFLP. Then total RNA extracted glass bead lysis buffer, cDNA synthesized using reverse transcriptase enzyme. RT-PCR (Reverse Transcriptase PCR) evaluate expression gene. Biofilm evaluated 96-well...
Abstract: Vulvovaginal candidiasis (VVC) is a mucous membrane infection, with an increased rate of antifungal resistance Candida species. The in vitro efficacy farnesol alone or combination traditional antifungals, against resistant strains recovered from women VVC was assessed. In this study, 80 isolats were identified by multi-plex PCR. Antifungal sus-ceptibility amphotericin B (AMB), fluconazole (FLU), itraconazole (ITZ), voriconazole (VOR), clotrimazole (CTZ) and tested M27-A3/S4 broth...
Background: Oral candidiasis (OC) has been noticed as a common mucous membrane infection in immunocompromised patients such that diabetes. This study, focused on the genotyping of Candida albicans and enzymatic activities species recovered from oral mucosa among diabetes healthy individuals. Materials Methods: Specimens were obtained One-hundred sixty with type 2 diabetic 108 All isolates definitely identified by ribosomal DNA (rDNA) gene sequencinghHydrophobicity, hemolytic genotypes C....
Background: Vulvovaginal candidiasis (VVC) is a common fungal infection caused by Candida species in the female genital tract. Objectives: This study attempts to predict predisposition VVC related risk factors and clinical symptoms among vaginitis cases using artificial neural network (ANN) model. Methods: cross-sectional was performed on 250 women referred gynecology clinics Birjand, Iran. A questionnaire used record participants' demographic information. Swabs were for wet mounts culture....
Otomycosis, as a common superficial fungal infection, is the term to infection of external auditory canal. Despite numerous studies on diverse antifungal agents, there no consent effective agent for treatment otomycosis. Therefore, purpose this study compared therapy otomycosis using two therapeutic agents; clotrimazole and iodine tincture.This research clinical trial included 160 patients who were presented All randomly assigned into groups Iodine Tincture (80 cases in each group). The...
Abstract Background:The aim of this study was to investigate and then compare the prevalence nosocomial infections (NIs) in patients admitted surgery internal Intensive Care Units(ICU) as well studying risk factors involved.Methods:In cross-sectional descriptive, ICUs were studied over a year .Clinical data patients, including demographic information, length stay, underlining disease, rate patient with NIs distribution sites pathogens collected. Univariate multivariate logestic regression...
Abstract Background: Candida albicans ( C. albicans) is an opportunistic fungus and the most common cause of vulvovaginal candidiasis (VVC). In recent years, use antifungal drugs has led to incidence drug resistance. The purpose this study two fold: determine relationship between risk factors resistance among isolates from women with VVC investigate expression pattern drug-resistance genes ERG11 TAC1 in using real-time PCR. Methods Results: This descriptive cross-sectional was conducted on...
In-Vitro Antifungal Activity of Nano Encapsulated Caprylic Acid and EFG1 Gene Expression Profile in Candida albicans
Abstract Background Aspergillus species are the reason for wide range of infections especially invasive fungal infections. The aim this study was defined to evaluate antifungal activity plants and compounds including thyme, Aloevera , Thyme carvacrol, nano-encapsulation carvacrol on growth aflatoxin production parasiticus flavus . Methods Results minimum inhibitory concentrations (MICs) extracts, nanocarvacrol, fluconazole as control were determined according Clinical Laboratory Standards...
Aim: This study aimed to identify Candida species recovered from the oral cavity of patients with kidney transplantation. Materials & methods: Two swabs were taken cavities 40 before and after transplantation, cultured on Sabouraud dextrose agar, yeasts identified. Antifungal drug susceptibility testing was performed fluconazole itraconazole. Results:Candida glabrata most frequently isolated in patients, followed by albicans Rhodotorula. C. isolates transplantation resistant fluconazole,...