A5045553525- Pancreatic function and diabetes
- Diabetes and associated disorders
- Thyroid Cancer Diagnosis and Treatment
- Diabetes Management and Research
- Glycogen Storage Diseases and Myoclonus
- Head and Neck Anomalies
- Urological Disorders and Treatments
- Health Sciences Research and Education
- BRCA gene mutations in cancer
- Innovations in Medical Education
- Genetics and Neurodevelopmental Disorders
- Sexual Differentiation and Disorders
- Adenosine and Purinergic Signaling
- Clinical Reasoning and Diagnostic Skills
- Diet, Metabolism, and Disease
- Infectious Encephalopathies and Encephalitis
- Health and Conflict Studies
- Oral and Craniofacial Lesions
- Herpesvirus Infections and Treatments
- Breastfeeding Practices and Influences
- Cleft Lip and Palate Research
- Streptococcal Infections and Treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hospital Admissions and Outcomes
- Neonatal Health and Biochemistry
Naval Medical Center Portsmouth
2011-2024
Uniformed Services University of the Health Sciences
2018-2019
Children's Hospital of Pittsburgh
2013-2015
University of Pittsburgh Medical Center
2015
Boston Children's Hospital
2014
Ankyloglossia has been associated with a variety of infant-feeding problems. Frenotomy commonly is performed for relief ankyloglossia, but there lack convincing data to support this practice.Our primary objective was determine whether frenotomy infants ankyloglossia improved maternal nipple pain and ability breastfeed. A secondary the length breastfeeding.Over 12-month period, neonates who had difficulty breastfeeding significant were enrolled in randomized, single-blinded, controlled trial...
The aim of this study was to test the hypothesis that our 60-gene DNA/RNA ThyroSeq v2 next-generation sequence (NGS) assay would identify additional genetic markers, including gene fusions in sporadic pediatric differentiated thyroid carcinomas (DTC) had no known molecular alterations. Sporadic DTCs with informative testing ( n = 18) were studied. We previously tested 15 cases by standard 7-gene BRAF, NRAS, HRAS, KRAS, RET/PTC1, RET/PTC3, PAX8/PPARg) mutation panel. Three not previously....
To evaluate the proportion of pediatric patients with concurrent diagnoses hyperthyroidism and mental health conditions (MHCs) by using Military Health System database. We hypothesized that prevalence disorders would be higher in compared nonhyperthyroid population.The MHCs was calculated data extracted from Data Repository on military beneficiaries between 10 18 years old who were eligible to receive care for at least 1 month during fiscal 2008 through 2016. Prevalence ratios used compare...
To describe the incidence and prevalence of type 1 diabetes among pediatric dependents US Department Defense.The Military Health System (MHS) data repository was used to identify patients (≤17 years age) with from January 1, 2007 December 31, 2012. Annual incidence, annual adjusted were calculated stratified by sex, age group, region residence.Within a 6-year study period 2012, 5616 identified; 57% male, mean (SD) 10.9 (4.2) years. (per 100 000 persons) over 5-year time ranged 20.7/100...
Papillary thyroid carcinoma (PTC) is rare in children, although it a known secondary malignancy after treatment for neuroblastoma (NB). The interval between NB completion and PTC usually more than 5 years. A 4-year-old, female patient with high risk adrenal was found to have 2.9-cm, right nodule on surveillance chest computed tomography (CT) 6 months of her (induction chemotherapy, tumor resection, autologous stem cell transplantation, external beam radiation the abdominal site,...
Abstract Background: Glycogen storage diseases (GSDs) are a collection of disorders related to glycogen synthesis or degradation that classically present in infancy with hypoglycemia, failure thrive and hepatomegaly; however, their phenotype can vary significantly. Case presentation: We the cases two children, 5 years old 3.5 old, who were referred endocrinology for short stature. They ultimately found have hepatomegaly, fasting mild elevation transaminases ketosis. Laboratory genetic...
OBJECTIVE Disease-associated T-cell autoreactivities are seen in most type 1 diabetic patients and thought to emerge before islet autoantibodies, but host factors that impact autoimmune elements remain uncertain. We assessed if adiposity measures of insulin sensitivity T- B-cell autoimmunity children with insulin-requiring diabetes. RESEARCH DESIGN AND METHODS Insulin-requiring adolescents diagnosed between January 2004 June 2008 were studied (n = 261): age 9.7 ± 4 years, 92% white, 60%...
Background: Wolfram syndrome is a genetic condition, which typically inherited in autosomal recessive fashion, characterized by the combination of diabetes mellitus and optic atrophy.It along spectrum encompasses DIDMOAD (Diabetes insipidus, mellitus, atrophy, deafness).Profound hypoglycemic unawareness can be seen this condition but not commonly described as an associated feature literature.Case report: A 16 year old female with history presumed type 1 presented to urology clinic urinary...
A 15-year-old boy presents with a 12-hour history of progressive confusion, slurred speech, and ataxia. He was seen earlier in the week for rhinorrhea, cough, fever diagnosed as having viral illness. His symptoms improved until 12 hours before presentation when he became moody, confused, ataxic. denies any weakness, headache, diarrhea, constipation, visual changes, neck stiffness, photophobia, or phonophobia. also toxic ingestions drug alcohol use. has not had immunizations recently. He...
Background: Type 1 diabetes (T1D) is a common and costly chronic disease in childhood. The SEARCH for Diabetes Youth Study estimated annual incidence of T1D the U.S. starting 2002 demonstrated steady rise, through most recent reported at 20.1/100,000 2008. While more current hasn’t been published, European nations with national registries have plateau incidence. Our study aimed to describe prevalence military dependent children using data from …
Introduction: Glycogen storage diseases (GSD) classically present in infancy with hypoglycemia, failure to thrive, and hepatomegaly; however their phenotype can vary significantly. We two children referred for short stature ultimately found have genetic mutations consistent GSD Ia III. Case Reports: Child A: Healthy 5-year-old male pediatric endocrinology stature. Parents reported history of tiredness when hungry intermittent headaches. Height SD was -2.4 (midparental height 10th...
Introduction: Navy Medical Corps officers frequently experience discontinuous residency training due to the Navy’s operational medicine structure. Many naval physicians serve in fleet as General Officers (GMOs) following internship and return after a gap training. This can span several years. Most GMOs have not practiced their chosen specialty during tour. is especially true of pediatric residents. There no formal evaluation process or curriculum guide resumption …
Disorders of sexual development are rare and carry high potential for medical psychosocial co-morbidities. A 4 year old female presented with non-reducible bilateral inguinal masses. Physical exam was consistent a healthy child normal external genitourinary exam, maturity rating 1. Elective general surgical repair scheduled. Pre-surgical ultrasound imaging revealed isolated loops bowel in each canal, no other masses, visualized cervix, non-visualized uterus. Further work up initiated upon...