A5051120191- Epigenetics and DNA Methylation
- Hedgehog Signaling Pathway Studies
- Veterinary Oncology Research
- Genomics and Chromatin Dynamics
- Cancer Cells and Metastasis
- Nutrition, Genetics, and Disease
- Single-cell and spatial transcriptomics
- Oral and Maxillofacial Pathology
- Cancer-related Molecular Pathways
- Genetics and Neurodevelopmental Disorders
Harvard University
2020-2024
Guru Angad Dev Veterinary and Animal Sciences University
2012-2014
Public Works Department Buildings and Roads
2014
Aging is closely associated with increased susceptibility to breast cancer, yet there have been limited systematic studies of aging-induced alterations in the mammary gland. Here, we leverage high-throughput single-cell RNA sequencing generate a detailed transcriptomic atlas young and aged murine tissues. By analyzing epithelial, stromal, immune cells, identify age-dependent cell proportions gene expression, providing evidence that suggests alveolar maturation physiological decline. The...
Transmissible venereal tumours (TVT) are normally seen on the genitalia of both male and female dogs, at times may be observed extra-genital sites such as lips, oral mucosa, peritoneum, or in organs tonsils, eye, liver, spleen, kidney, lung, musculature. The present communication deals with two rare cases primary extragenital TVT involving mammary glands dogs their pathology immunohistochemistry. study indicated that apart from routinely used markers vimentin, p53, PCNA, Ki-67 c-myc,...
The retinoblastoma susceptibility gene RB-1 is a tumour suppressor that encodes protein (Rb) regulates the transition from G1 phase to S of cell cycle. Inactivation Rb has been shown in variety human tumours, including breast, ovarian, hepatic, prostatic, and endometrial carcinomas. Although normally expressed nuclei healthy cells, during carcinogenesis there partial or complete loss nuclear expression. Recently, some reports have indicated aberrant cytoplasmic expression protein. However,...