- Pancreatic function and diabetes
- Diabetes and associated disorders
- Diabetes Management and Research
- Environmental DNA in Biodiversity Studies
- Aquatic Invertebrate Ecology and Behavior
- Freshwater macroinvertebrate diversity and ecology
- Subterranean biodiversity and taxonomy
- Soil and Water Nutrient Dynamics
- Philosophy, Science, and History
- German Literature and Culture Studies
- Species Distribution and Climate Change
- Fish Ecology and Management Studies
- Ecology and biodiversity studies
- Hydrology and Watershed Management Studies
- Birth, Development, and Health
- Historical, Literary, and Cultural Studies
- Groundwater and Isotope Geochemistry
- Pancreatitis Pathology and Treatment
- Immune Cell Function and Interaction
- Karst Systems and Hydrogeology
- Diet, Metabolism, and Disease
- T-cell and B-cell Immunology
- Peatlands and Wetlands Ecology
- Renal Transplantation Outcomes and Treatments
- Cannabis and Cannabinoid Research
University of Koblenz and Landau
2011-2024
University of Lucerne
2024
Goethe University Frankfurt
1950-2024
University of Göttingen
2024
Technical University of Darmstadt
2024
RWTH Aachen University
2024
Johannes Gutenberg University Mainz
2024
Folkwang University of the Arts
2024
University of Siegen
2024
Universität Koblenz
2004-2023
Global freshwater biodiversity is declining dramatically, and meeting the challenges of this crisis requires bold goals mobilisation substantial resources. While reasons are varied, investments in both research conservation lag far behind those terrestrial marine realms. Inspired by a global consultation, we identify 15 pressing priority needs, grouped into five areas, an effort to support informed stewardship biodiversity. The proposed agenda aims advance globally as critical step improving...
Summary 1. Classification of groundwater habitats and communities at different spatial scales is emphasised as a basic requirement for the implementation ecology into legislation. Such classification would also facilitate prediction biodiversity, abundance community structure, but not currently available. 2. To identify factors influencing distribution stygofauna landscape scale, fauna Baden–Württemberg in South‐western Germany was sampled from November 2001 to December 2002. A total 304...
The use of ecological criteria for the assessment aquatic ecosystem status is routine surface waters. So far no parameters are considered and monitoring groundwater quality. It has been well known decades that aquifers ecosystems harbouring a vast diversity invertebrates microorganisms. growing knowledge on microbial faunal communities as molecular statistical tools available form solid ground development first ecologically sound schemes. sensitivity towards impacts from land waters...
Only a few low-temperature aquifer thermal energy storage sites (LT-ATES) exist in Germany. Our project aims to demonstrate the implementation of LT-ATES system an urban area motivated by increasing demand for cooling summer. The backyard office building complex Berlin-Mitte was chosen as our test site. Due densely built-up conditions, it not possible implement classic doublet system. A coaxial well with drilling depth 27 m and filter distance 6 therefore implemented, which can only be...
Linked to diverse biological processes, groundwater ecosystems deliver essential services mankind, the most important of which is provision drinking water. In contrast surface waters, ecological aspects systems are ignored by current European Union and national legislation. Groundwater management protection measures refer exclusively its good physicochemical quantitative status. Current initiatives in developing ecologically sound integrative assessment schemes taking fauna into account...
Implementation of the European Union (EU) Water Framework Directive (WFD 2000) and its planned supplement ‘Directive on Protection Groundwater against Pollution’ (EU GWD [European Directive] 2003) demands an initial characterization all groundwater bodies by national regional authorities. The main criteria considered in Directives to define (GW) status are quality (chemical) quantity, but there is obvious omission ecological perspective these. A directive for a comprehensive policy dealing...
Abstract The BioBreeding (BB) rat develops spontaneously a syndrome resembling human type I diabetes mellitus. short‐term treatment of newly diagnosed diabetic BB rats with the anti‐interleukin 2 receptor (IL2R) monoclonal antibody ART‐18 in combination subtherapeutic dose cyclosporin A for 10 days, shown previously to eliminate specifically antigen‐activated IL 2R + T lymphocytes by sparing suppressor cells, resulted (a) normoglycemia 70% animals, (b) maintenance B cell volume density and...
Abstract Suppressor T cells of humoral immune responses, effector mediating DTH, suppressor and helper all with specificity to SRBC, were produced in mice. The biologic activity was tested adoptive transfer experiments. In vitro treatment different doses 4-hydroperoxycyclophosphamide (4-HPCy) yielded the result that various activities not uniformly sensitive action this drug: responses DTH resistant 4-HPCy eliminated response. These findings help explain effects cyclophosphamide has on vivo...
The effect of Entamoeba histolytica extracts (E.h.e.) on proliferation in vitro human peripheral blood lymphocytes, cord and lymphocytes enriched for T cells or non-T was investigated. As tested by 3H-thymidine uptake morphologic criteria, E.h.e. stimulate lymphocyte proliferation. Non-T do not respond to response differed from their Con A several respects, indicating either that act different subsets mechanism the reactive cells.
Abstract. In Germany, 70 % of the drinking water demand is met by groundwater, for which quality product multiple physical–chemical and biological processes. As healthy groundwater ecosystems help to provide clean water, it necessary assess their ecological conditions. This particularly true densely populated urban areas, where faunistic investigations are still scarce. The aim this study is, therefore, a first assessment fauna in an area. Thus, we examine status anthropogenically influenced...
Abstract: We have investigated the effect of non‐immunosuppressive cyclosporin A (CS‐A) doses on glucose tolerance, pancreatic insulin content, content isolated islets and secretion in vitro response to glucose. Within 12 weeks animals treated permanently with a dose 2.5 mg CS‐A/kg b.wt. developed intolerance (but not hyperglycaemia) accompanied by decrease due islet whereas relative B‐cell volume density was.not changed. Isolated obtained from rats for 4 had diminished sensitivity glucose,...