- Language Development and Disorders
- Childhood Cancer Survivors' Quality of Life
- Autism Spectrum Disorder Research
- Neurobiology of Language and Bilingualism
- Glioma Diagnosis and Treatment
- Traumatic Brain Injury Research
- Genetics and Neurodevelopmental Disorders
- Family and Disability Support Research
- Child Development and Digital Technology
- Acute Lymphoblastic Leukemia research
- Infant Development and Preterm Care
- Cancer-related cognitive impairment studies
- Cancer and Skin Lesions
- Metabolism and Genetic Disorders
- Oral Health Pathology and Treatment
- Contact Dermatitis and Allergies
- Meningioma and schwannoma management
- Oral and Craniofacial Lesions
- Neonatal Health and Biochemistry
- Autoimmune Bullous Skin Diseases
- Mitochondrial Function and Pathology
- Cardiac Arrest and Resuscitation
- Palliative Care and End-of-Life Issues
- Reading and Literacy Development
- Child and Animal Learning Development
The University of Queensland
1998-2017
Guy's and St Thomas' NHS Foundation Trust
2016
Wexham Park Hospital
2009-2013
St Thomas' Hospital
2009
Speech Pathology Australia
2007
Royal Hallamshire Hospital
1996
Abstract Increasingly, researchers and clinicians are beginning to unveil both cognitive linguistic impairments in Parkinson's disease (PD), a condition characterized the past primarily by impairment of motoric aspects ambulation speech. This study describes subtle language 20 subjects with PD on battery measures selected be sensitive frontal lobe function. Comparative performances an age, gender, education-matched control group revealed significant performance level differences across...
Purpose: This study investigated if the quality of pre-school children's pretend play predicted their semantic organization and narrative re-telling ability when they were in early primary school. It was hypothesized that elaborateness a child's use symbols predictors re-tell scores School Age Oral Language Assessment.
Intrathecal chemotherapy (ITC) is the treatment option for acute lymphoblastic leukaemia (ALL). Neurocognitive deficits have been described following ITC, but language status post-treatment yet to be clarified. This study examined skills of nine children ITC ALL (mean age 7;8 years and 3;2 post-diagnosis at baseline measurement) age- sex-matched controls, then 2 later, using a battery tests assessing general skills. An assessment cognitively-demanding high level was undertaken on sub-group...
The language skills of 4 children treated for tumors involving the cerebellum and/or fourth ventricle with risk-adapted treatments were compared, as a group, performance group control (n = 20). individual cases also profiled. At level, skill failed to differentiate 2 groups children. an however, only 1 presented intact skills. Variable profiles identified in remaining 3 presence hydrocephaly was consistent factor reduced outcomes. findings highlight importance prospective monitoring.
Educational achievement, which for individuals with the metabolic disorder classic galactosemia (GAL) is significantly lower than in wider population, correlates self-reported quality of life. Phonological awareness skills underpin development literacy, and although literacy a key contributor to successful academic outcomes, no study date has investigated phonological children GAL. This (PA) four school-aged disorder, two whom were siblings. Age range was 7 years months 9 2 months. Each...
Up to 85% of children treated for brain tumor survive beyond five years; hence optimizing quality life in survivorship has become a priority. As multiple factors contribute the heterogeneity neurocognitive and language outcomes individua
Objective: Recent research findings suggested that children treated for medulloblastoma (MB) may experience undiagnosed language difficulties following treatment. The aim of this report was to investigate skills in an adolescent treatment MB.Methods: This single case study profiles the GCG, a female aged 14;1 years, who with risk-adapted cranial radiation therapy (CRT) MB 4 years prior assessment.Results: Difficulties recalling verbal information increasing length and complexity reduced...
Pre- and post-injury language performance scores following mild traumatic brain injury (mTBI) were investigated through a replication subsequent extension of previous case study where trend for declining was described based on pre- data.Test norms used to descriptively analyze post-morbid score changes. Score changes subsequently statistically analyzed using data obtained from group age-matched non-brain-injured control children.Descriptive analysis identified skill general high-level...
Studies are emerging that suggest major language indices do not differentiate children treated for acute lymphoblastic leukemia (ALL) with risk-adapted intrathecal chemotherapy (ITC) from control matched on age, gender, and educational level. No study to date has controlled cognitive environment, an important variable influencing achievement outcome. This case-control applies the deconfounding principle by using a sibling as investigate outcomes in male child 11 years after administration of...
Background: Neonatal screening for galactosaemia (GAL) identifies the condition early, but subsequent biomedical and genetic testing fails to identify which subgroup of infants with GAL are at most risk language disorders associated condition. This study aims present preliminary data on an infant based assessment pre-linguistic communication behaviours known underpin development.Methods: single case-control profiles skills a 13-month-old GAL. The Index Infant's performance was descriptively...
Central nervous system (CNS)-directed chemotherapy is delivered for the treatment of childhood acute lymphoblastic leukaemia (ALL). Figurative language deficits have been described in children following CNS-directed chemotherapy; however, comprehensive analysis figurative interpretation errors, potentially providing clinical utility to assist with intervention planning, has never performed. The present study aimed compare skills seven treated ALL before age 6 years (mean at diagnosis 3 10...
Using cross-sectional and longitudinal approaches, the current research investigated language skills of two boys following CNS-targeted chemotherapy-only treatment for acute lymphoblastic leukaemia. A single case-multiple comparison study each boy's general skills, as assessed by Clinical Evaluation Language Fundamentals-Fourth Edition, Peabody Picture Vocabulary Test-Third Edition Form A, Hundred Pictures Naming Test, high level Test Competence-Expanded Problem Solving-Elementary, Revised...
Purpose: Central nervous system (CNS) prophylaxis in the treatment of childhood acute lymphoblastic leukaemia (ALL) is routinely achieved through intrathecal chemotherapy (ITC). The presence high level language deficits older children who received CNS-directed ITC for ALL early yet to be elucidated, with previous research suggesting that may appear later survivors' development at an age when these skills typically emerge.Method: A test battery covering foundational and higher-order was...