There is no agreement as to which variable best mirrors disease activity in rheumatoid arthritis (RA) and studies have been performed on the validity of variables. In this study 10 commonly used single variables three composite indices was tested. All patients participated a large follow up two clinics. The (n = 233) had classical or definite RA duration less than one year at entry. mean time 30 months; frequency once every four weeks; 6011 records were analysis. validation criteria included...

Journal Article PROGNOSTIC FACTORS FOR RADIOGRAPHIC DAMAGE AND PHYSICAL DISABILITY IN EARLY RHEUMATOID ARTHRITIS. A PROSPECTIVE FOLLOW-UP STUDY OF 147 PATIENTS Get access D. M. F. VAN DER HEIJDE, HEIJDE *Department of Rheumatology, University Hospital NijmegenThe Netherlands Correspondence to Désirée van der Heijde, MD, Department Nijmegen, PO Box 9101, 6500 HB The Search for other works by this author on: Oxford Academic PubMed Google Scholar P. L. C. RIEL, RIEL A. LEEUWEN, LEEUWEN...

A clinical trial, concerning 203 resin-bonded bridges (RBBs), was performed for investigation of the influence retainer-type and cementation materials on survival these restorations. The rates after a 7.5-year follow-up were 75% anterior RBBs 44% posterior bridges. Etched metal (E-bridges) significantly more retentive than perforated (P-bridges); 78% 63%, respectively. With respect to materials, Clearfil F, in combination with E-bridges, had best overall (89%, posterior). Maxillary...

In 2002 a dental survey amongst 6- and 12-year-old schoolchildren (n = 832) in The Hague was carried out. caries findings were compared with from earlier studies Hague. Caries prevalence (% of caries-free children) experience (mean dmfs scores) among 6-year-old children had not changed significantly the period 1996-2002. However, significant increase low socio-economic status found proportions Dutch, Turkish Moroccan 88, 69 78%, respectively, 2002. average DMFT score 12-year-olds reached...

The present randomised clinical trial was aimed at comparing three minimally invasive restorative treatment approaches for managing dental caries in occlusal surfaces using a non-gamma-2 amalgam and low-viscosity glass-ionomer as the material. tested parallel groups were: conventional university setting, modified-conventional ultraconservative (Atraumatic Restorative Treatment, ART) field setting. A split-mouth design used which two materials were randomly placed 430 matched contralateral...

The aim of the present trial was to (1) compare caries-preventive effect glass ionomer sealants, placed according atraumatic restorative treatment (ART) procedure, with composite resin sealants over time and (2) investigate after complete disappearance sealant material. Forty-six boys 57 girls, mean age 7.8 years, were randomly divided into two groups in a parallel-group study design. A light-polymerized material high-viscosity each 180 fully erupted first molars their respective groups....

Summary In this article the results are presented of an evaluation crowns and bridges in a general practice. The study includes 601 solitary crowns, 213 on bridge abutments 103 RPD abutments. total eighty‐four were examined. All these restorations constructed during period 11.5 years. By means Kaplan‐Meier method prognosis is given life span different crown‐types over periods between 1 11 amount failures follow‐up treatments was very small. authors also examined whether according Ante's law....

Microplastics require a risk assessment framework that takes their multidimensionality into account while exclusively considering robust data. Therefore, effect tests should use diverse, environmentally relevant microplastic (ERMP) standard material adheres to high-quality requirements. In this study, we provide chronic dose–effect relationships and thresholds for 16 benthic species exposed ERMP. The ERMP was created from plastic items collected natural sources cryogenically milled represent...

Increasing water consumption, industrial pollution, and long dry periods – these are all resource challenges that highlight the growing importance of transition towards a circular economy for soil-sediment-water system. As described by European Green Deal call, pollution persistent, mobile potentially toxic (PM(T)) substances is often systemic problem. It related to ways production, use, emission chemicals aggravated missing technical solutions monitoring techniques in This poses...

Achieving remission in rheumatoid arthritis (RA) remains elusive despite current biological therapeutics. Consequently, interest has increased strategies to re-establish immune tolerance provide long-term disease suppression. Although dendritic cells (DC) are prime candidates initiating autoreactive T cell responses, and their presence within the synovial environment suggests a role generation maintenance of autoreactive, functional importance unclear. We investigated contribution made by...

Abstract The effect of hand or ultrasonic instrumentation on the subgingival microflora periodontal pockets was investigated. Pockets with probing depths 6‐9 mm were selected in 12 patients and randomly assigned per patient to experimental control groups. After oral hygiene instruction, carried out either by instruments a split‐mouth design. treatment microbiota evaluated microscopic culture studies plaque samples, while addition, supragingival plaque, bleeding after pocket depth scored....

A nationwide survey of oral conditions, treatment needs, and attitudes toward dental health care in Dutch adults was carried out 1986. One the aims study to investigate perceived need demand for craniomandibular dysfunction (CMD). sample 6577 persons (15-74 yrs age), stratified gender, age, region, socio-economic status, contacted. Of this sample, 4496 participated behavioral part study, which 3526 were examined clinically. The CMD-treatment based on (1) CMD complaints past, (2) at present,...

To compare efficacy, toxicity, and the pharmacokinetics of combination sulphasalazine (SASP) methotrexate (MTX) vs MTX alone in treatment SASP-resistant RA we conducted a controlled open clinical trial. Forty patients with active arthritis despite adequate SASP therapy, were allocated randomly to regimes either + or alone. The evaluated openly by single observer for 24 weeks. In first 15 using combination, without studied. Thirty-eight completed mean decrease disease activity score group...

Abstract The clinical and microbiological effect of locally‐applied chlorhexidine gel 2%, amine fluoride 1.25%, stannous 4% or placebo in 40 periodontal pockets 10 patients were studied. gels applied 3 x within min. after mechanical debridement the pockets. treatment on subgingival microflora was evaluated by microscopic culture studies plaque samples. In addition, supragingival plaque, bleeding probing pocket depth scored. Examination carried out before during a period 36 weeks treatment....

The present study was aimed at comparing the effectiveness of three minimally invasive restorative treatment approaches for dentinal lesions in occlusal surfaces. tested comprised a conventional and modified–conventional modified Atraumatic Restorative Treatment (ART). approach performed university dental clinic whilst modified–conventional, employing portable equipment, ART, using hand instruments caries removal solution (Caridex<sup>®</sup>), were carried out field. Using...

The long-term use of second-line antirheumatic drugs was prospectively studied in a consecutive sample 245 patients with recently diagnosed rheumatoid arthritis. A survival analysis done which treatment termination due to side-effects and insufficient therapeutic effect were used as index causes. Cumulative drug ‘survival’ aurothioglucose toxicity significantly less compared hydroxychioroquine. With regard lack efficacy cause, the administration time hydroxychloroquine than that either or...