- Digital Mental Health Interventions
- Impact of Technology on Adolescents
- Child Development and Digital Technology
- Social Media in Health Education
- Immune Cell Function and Interaction
- Telemedicine and Telehealth Implementation
- Health Literacy and Information Accessibility
- Social Media and Politics
- Acute Lymphoblastic Leukemia research
- Traumatic Brain Injury Research
- Mental Health Research Topics
- Hematopoietic Stem Cell Transplantation
- Child and Adolescent Psychosocial and Emotional Development
- Chronic Myeloid Leukemia Treatments
- DNA Repair Mechanisms
- Immunotherapy and Immune Responses
- Virtual Reality Applications and Impacts
- Mental Health and Patient Involvement
- Mindfulness and Compassion Interventions
- Reproductive System and Pregnancy
- Mental Health Treatment and Access
- Pediatric Pain Management Techniques
- Empathy and Medical Education
- Music Therapy and Health
- Healthcare professionals’ stress and burnout
The University of Sydney
2014-2024
Google (United States)
2022
University of North Texas
2021
Malden Public Schools
2021
Hudson Institute
2021
Hood College
2021
Cardiff University
2020
Lancaster University
2020
University of Rochester
2006-2019
University of Rochester Medical Center
2010-2019
Use of the Internet by seniors as a communication technology may lead to changes in older adult social relationships. This study used an online questionnaire survey 222 Australians over 55 years age on use. Respondents primarily for communication, seeking information, and commercial purposes. The results showed negative correlations between loneliness well-being. Multiple regression analyses revealed that greater use tool was associated with lower level loneliness. In contrast, find new...
Amyloid protein is well known to induce neuronal cell death, whereas only little about its effect on astrocytes. We found that amyloid peptides activated caspase 3 and induced apoptosis in primary cultured astrocytes, which was prevented by inhibition. Apoptosis also shRNA-mediated down-regulation of PAR-4, a sensitizing cells the sphingolipid ceramide. Consistent with potentially proapoptotic PAR-4 ceramide, astrocytes surrounding plaques brain sections 5xFAD mouse (and Alzheimer disease...
The Internet has often been argued to have adverse psychological consequences, such as depression or anxiety symptoms, among "over-users." present study offers an alternative understanding, suggesting the may be used a forum for expanding social networks and consequently enhancing chance of meaningful relationships, self-confidence, abilities, support. An online sample 188 people was recruited over Internet, while paper pencil tests were administered offline group 27 undergraduate university...
Abstract Introduction and Aims. Alcohol is a key component of identity exploration for many young people, yet few studies have investigated construction in relation to problematic drinking. Increases youth alcohol consumption coincided with expanding use communications technologies, particularly social networking sites (SNS), which altered traditional conditions construction. It has been found people often engage the SNS environment by portraying themselves as binge drinkers. The current...
Despite the efficacy of cognitive-behavioral therapy (CBT) in treating adolescent anxiety, few sufferers seek treatment. Barriers to accessing psychologists include a shortage skilled therapists, long waiting lists, and affordability. The Internet is medium possibly able address issues accessibility This study aimed assess online treatment prevention anxiety depression. Participants (N = 38) were randomly allocated one four conditions: CBT, face-to-face combined face-to-face/online control....
Abstract Introduction and Aims University students usually overestimate peer alcohol use, resulting in them ‘drinking up’ to perceived norms. Social norms theory suggests correcting these inflated perceptions can reduce consumption. Recent findings by the current authors show portraying oneself as ‘a drinker’ is considered many be a socially desirable component of their Facebook identity, perpetuating an online culture that normalises binge drinking. However, social networking sites have yet...
Digital mental health services are becoming increasingly valuable for addressing the global public burden of ill-health. There is significant demand scalable and effective web-based services. Artificial intelligence (AI) has potential to improve through deployment chatbots. These chatbots can provide round-the-clock support triage individuals who reluctant access traditional care due stigma. The aim this viewpoint paper consider feasibility AI-powered platforms well-being. Leora model...
Objective: To document the sociodemographic characteristics and online use patterns of older Australian Internet users as part an exploratory study relationship between communication access to social capital in later life. Methods: A purposive sample 154 aged 55 years or not employed full time completed electronic survey about their use. subsample 30 participated follow‐up in‐depth interviews. Results: The majority participants comprised married, home‐owning, English‐speaking women men good...
Walking meditation is a form of mindfulness training, where the act walking provides rhythmic meter for attentional focus. Whilst digital technologies to support sitting and practices exist, less explored first person in-the-moment experience technology-mediated meditation. We present study group meditation, with without an interactive soundscape modulated by one practitioner's brainwave data. Six workshops were conducted novice advanced practitioners, involving guided body scan, writing...
Background. Janus kinase 3 (JAK3) mediates signal transduction from cytokine receptors using the common chain (γc). Because mutations in genes encoding γc or JAK3 result immunodeficiency, we investigated potential of a rationally designed inhibitor JAK3, CP-690,550, to prevent renal allograft rejection nonhuman primates. Methods. Life-supporting kidney transplantations were performed between mixed leukocyte reaction-mismatched, ABO blood group-matched cynomolgus monkeys. Animals treated with...
Background. Janus Kinase (JAK) 3 is a tyrosine kinase essential for proper signal transduction downstream of selected cytokine receptors and robust T-cell natural killer cells activation function. JAK3 inhibition with CP-690,550 prevents acute allograft rejection. To provide further insight into the mechanisms efficacy, we investigated immunomodulatory effects in vitro vivo nonhuman primates. Methods. Pharmacodynamic assessments lymphocyte activation, function, proliferation phenotype were...