Nicholas Belt

ORCID: 0000-0002-2234-1872
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About
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Research Areas
  • Metabolism and Genetic Disorders
  • Folate and B Vitamins Research
  • Amino Acid Enzymes and Metabolism

University of Alabama
2021

Methylxanthines, including caffeine and theophylline, are a class of natural synthetic compounds with important roles in food, cosmetics, medicine. These metabolized by bacteria using five enzymes from the Rieske non-heme iron oxygenase family, NdmABCDE. The NdmCDE complex is responsible for N7-demethylation 7-methylxanthine to xanthine was originally described as being highly specific 7-methylxanthine. Here, we report that also active toward theobromine, producing 3-methylxanthine due...

10.1016/j.biotno.2021.05.001 article EN Biotechnology Notes 2021-01-01
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