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Research Areas
- Metabolism and Genetic Disorders
- Folate and B Vitamins Research
- Amino Acid Enzymes and Metabolism
University of Alabama
2021
Methylxanthines, including caffeine and theophylline, are a class of natural synthetic compounds with important roles in food, cosmetics, medicine. These metabolized by bacteria using five enzymes from the Rieske non-heme iron oxygenase family, NdmABCDE. The NdmCDE complex is responsible for N7-demethylation 7-methylxanthine to xanthine was originally described as being highly specific 7-methylxanthine. Here, we report that also active toward theobromine, producing 3-methylxanthine due...
10.1016/j.biotno.2021.05.001
article
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Biotechnology Notes
2021-01-01
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