Ellen M. Howerton
A5033265281- Genetics and Neurodevelopmental Disorders
- Genomics and Rare Diseases
- RNA regulation and disease
- Autism Spectrum Disorder Research
- Genomic variations and chromosomal abnormalities
- RNA and protein synthesis mechanisms
- Child Nutrition and Feeding Issues
- Metabolism and Genetic Disorders
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Mitochondrial Function and Pathology
- Family and Disability Support Research
- Congenital heart defects research
- Prenatal Substance Exposure Effects
- Metabolomics and Mass Spectrometry Studies
- Genetic Associations and Epidemiology
- ATP Synthase and ATPases Research
- Genomics and Phylogenetic Studies
- Chromatin Remodeling and Cancer
- Maternal Mental Health During Pregnancy and Postpartum
- Fluorine in Organic Chemistry
- Birth, Development, and Health
- Child and Adolescent Health
- Migration, Health and Trauma
- Endoplasmic Reticulum Stress and Disease
Johns Hopkins University
2021-2025
National Institutes of Health
2021
Autism spectrum disorder (ASD). 2022. The and Developmental Disabilities Monitoring Network is an active surveillance program that estimates prevalence characteristics of ASD monitors timing identification among children aged 4 8 years. In 2022, a total 16 sites (located in Arizona, Arkansas, California, Georgia, Indiana, Maryland, Minnesota, Missouri, New Jersey, Pennsylvania, Puerto Rico, Tennessee, Texas [two sites: Austin Laredo], Utah, Wisconsin) conducted for years suspected...
Importance Prior literature has explored the prevalence of motor impairments in autistic individuals, but estimates come from clinical, convenience, or small samples, limiting generalizability. Better understanding frequency milestone delays individuals could improve early identification and subsequently lead to earlier intervention better developmental outcomes. Objective To determine a population-based sample 8-year-old children evaluate if having is associated with an age at autism...
This study aims to clarify relationships of maternal psychiatric conditions and selective serotonin reuptake inhibitor (SSRI) use during preconception pregnancy with risk neurodevelopmental disorders in offspring.We used data from the Study Explore Early Development, a multisite case-control conducted United States among children born between 2003 2011. Final group classifications autism spectrum disorder (ASD) (n = 1367), developmental delays or (DDs) 1750), general population controls...
Gestation is a vulnerable window when exposure to per- and polyfluoroalkyl substances (PFAS) may impact child development health. Epigenetic modification, including DNA methylation (DNAm), be one mechanism linking prenatal PFAS offspring outcomes. We tested associations between newborn DNAm in 1017 participants from 6 cohorts the US Environmental influences on Child Health Outcomes consortium. Concentrations of [perfluorooctanesulfonic acid (PFOS), perfluorooctanoic (PFOA),...
Abstract Background : Blood DNA methylation patterns are highly predictive of prenatal exposure to smoking and differential has been associated with maternal alcohol use. We extended this determine whether in cord blood opioid, cannabis, polysubstance also evaluated have utility. Methods examined 932 mother-child pairs the Boston Birth Cohort between 1998-2020 substance use data. For each substance, we performed adjusted linear regression analysis at 865,859 CpG sites identify related...