A5077350027- Birth, Development, and Health
- Obesity, Physical Activity, Diet
- Gestational Diabetes Research and Management
- Breastfeeding Practices and Influences
- Pregnancy and preeclampsia studies
- Per- and polyfluoroalkyl substances research
- Epigenetics and DNA Methylation
- Air Quality and Health Impacts
- Child Nutrition and Water Access
- Asthma and respiratory diseases
- Nutritional Studies and Diet
- Heavy Metal Exposure and Toxicity
- Noise Effects and Management
- Maternal Mental Health During Pregnancy and Postpartum
- Child Nutrition and Feeding Issues
- Neonatal Respiratory Health Research
- Health, Environment, Cognitive Aging
- Infant Nutrition and Health
- Infant Development and Preterm Care
- Effects and risks of endocrine disrupting chemicals
- Bariatric Surgery and Outcomes
- Climate Change and Health Impacts
- Childhood Cancer Survivors' Quality of Life
- Diet and metabolism studies
- Fatty Acid Research and Health
Harvard Pilgrim Health Care
2016-2025
Harvard University
2016-2025
University of Washington
2025
Brigham and Women's Hospital
2009-2024
Boston University
1995-2024
Rush University Medical Center
2024
Cohort (United Kingdom)
2024
Harvard University Press
2019-2023
Stanford University
2023
Johns Hopkins University
2022
Fully understanding the determinants and sequelae of fetal growth requires a continuous measure birth weight adjusted for gestational age. Published United States reference data, however, provide estimates only median lowest highest 5th 10th percentiles at each The purpose our analysis was to create more measures age use in epidemiologic analyses. We used data from most recent nationwide Natality datasets generate multiple completed week gestation 22 through 44 weeks. Gestational determined...
Fish and other seafood may contain organic mercury but also beneficial nutrients such as n-3 polyunsaturated fatty acids. We endeavored to study whether maternal fish consumption during pregnancy harms or benefits fetal brain development. examined associations of intake hair at delivery with infant cognition among 135 mother–infant pairs in Project Viva, a prospective U.S. child cohort study. assessed by the percent novelty preference on visual recognition memory (VRM) testing 6 months age....
<h3>Objective</h3> To examine the extent to which infant sleep duration is associated with overweight at age 3 years. <h3>Design</h3> Longitudinal survey. <h3>Setting</h3> Multisite group practice in Massachusetts. <h3>Participants</h3> Nine hundred fifteen children Project Viva, a prospective cohort. <h3>Main Exposure</h3> At children's ages 6 months, 1 year, and 2 years, mothers reported number of hours their slept 24-hour period, from we calculated weighted average daily sleep. Outcome...
To study associations of maternal gestational weight gain with offspring status in adolescence.We surveyed 11,994 adolescents aged 9-14 years enrolled the Growing Up Today Study cohort and their mothers, members Nurses' Health II. We used multivariable linear logistic regression to adiposity.Mean (standard deviation) was 31.5 (11.2) pounds, body mass index (BMI) z score (BMI standardized for age sex) 0.15 (1.0) units; 6.5% were obese 95th percentile or higher) is calculated as [kg]/[height...
OBJECTIVE. The goal was to examine the associations of weight-for-length at birth and 6 months with obesity 3 years age. METHODS. We studied 559 children in Project Viva, an ongoing, prospective, cohort study pregnant women their children. measured length weight birth, months, years. Our main exposures were z score adjusted for gestational age birth. used multivariate regression analyses predict independent effects and, separately, 6-month on BMI score, sum subscapular triceps skinfold...
To examine the association between timing of introduction solid foods during infancy and obesity at 3 years age.We studied 847 children in Project Viva, a prospective pre-birth cohort study. The primary outcome was age (BMI for gender ≥ 95th percentile). exposure foods, categorized as <4, 4 to 5, 6 months. We ran separate logistic regression models infants who were breastfed least months ("breastfed") never or stopped breastfeeding before four ("formula-fed"), adjusting child maternal...
We established Project Viva to examine prenatal diet and other factors in relation maternal child health. recruited pregnant women at their initial visit eastern Massachusetts between 1999 2002. Exclusion criteria included multiple gestation, inability answer questions English, gestational age ≥22 weeks recruitment plans move away before delivery. completed in-person visits with mothers during pregnancy the late first (median 9.9 of gestation) second 27.9 weeks) trimesters. saw children...
The authors investigated the rate of gestational weight gain associated with lowest combined risk 5 short- and longer-term maternal child health outcomes for 2,012 mother-child pairs recruited in 1999–2002 into Project Viva, a prebirth cohort study Massachusetts. Within each prepregnancy body mass index (BMI, kg/m2) stratum, they performed logistic regression analysis predicting all outcomes, from which determined at average predicted prevalence adverse was lowest. mean total 0.39 kg/week...
To examine whether delivery by caesarean section is a risk factor for childhood obesity.Prospective prebirth cohort study (Project Viva).Eight outpatient multi-specialty practices based in the Boston, Massachusetts area.We recruited women during early pregnancy between 1999 and 2002, followed their children after birth. We included 1255 with body composition measured at 3 years of age.BMI score, obesity (BMI age sex ≥95th percentile), sum triceps plus subscapular skinfold thicknesses age.284...
Breastfeeding may benefit child cognitive development, but few studies have quantified breastfeeding duration or exclusivity, nor has any study to date examined the role of maternal diet during lactation on cognition.To examine relationships and exclusivity with cognition at ages 3 7 years evaluate extent which fish intake modifies associations infant feeding later cognition.Prospective cohort (Project Viva), a US prebirth that enrolled mothers from April 22, 1999, July 31, 2002, followed up...
The nasal cellular epigenome may serve as biomarker of airway disease and environmental response. Here we collect swabs from the anterior nares 547 children (mean-age 12.9 y), measure DNA methylation (DNAm) with Infinium MethylationEPIC BeadChip. We perform Epigenome-Wide Association analyses (EWAS) current asthma, allergen sensitization, allergic rhinitis, fractional exhaled nitric oxide (FeNO) lung function. find multiple differentially methylated CpGs (FDR < 0.05) Regions (DMRs; ≥ 5-CpGs...
Inadequate sleep duration and quality increase the risk of obesity. Sleep timing, while less studied, is important in adolescents because increasing evening preferences (chronotypes), early school start times, irregular schedules may cause circadian misalignment.To investigate associations chronotype social jet lag with adiposity cardiometabolic young adolescents.Starting 1999, Project Viva recruited pregnant women from eastern Massachusetts. Mother-child in-person visits occurred throughout...