A5103079269- Plant nutrient uptake and metabolism
- Plant Molecular Biology Research
- Plant Reproductive Biology
- Developmental Biology and Gene Regulation
- RNA Research and Splicing
- Axon Guidance and Neuronal Signaling
- Polysaccharides and Plant Cell Walls
- Skin and Cellular Biology Research
- Hearing, Cochlea, Tinnitus, Genetics
- Hair Growth and Disorders
- Chromosomal and Genetic Variations
University of Lausanne
2018-2023
École Polytechnique Fédérale de Lausanne
2007-2022
Abstract Angiosperms have evolved the phloem for long-distance transport of metabolites. The complex process development involves genes that only occur in vascular plant lineages. For example, Arabidopsis thaliana, BREVIS RADIX (BRX) gene is required continuous root protophloem differentiation, together with PROTEIN KINASE ASSOCIATED WITH BRX (PAX). and its BRX-LIKE (BRXL) homologs are composed four highly conserved domains including signature tandem separated by variable spacers....
Abstract Trajectories of cellular ontogeny are tightly controlled and often involve feedback-regulated molecular antagonism. For example, sieve element differentiation along developing protophloem cell files Arabidopsis roots requires two antagonistic regulators auxin efflux. Paradoxically, loss-of-function in either regulator triggers similar, seemingly stochastic failures individual precursors. Here we show that these patterning defects distinct non-random. They can be explained by...
mutant mice are one of the rare strains that do not develop whisker hair follicles while still displaying a pelage. Here, we show
Abstract Whiskers (vibrissae) are miniaturized organs that designed for tactile sensing. Extremely conserved among mammals, they underwent a reduction in primates and disappeared the human lineage. Furthermore, whiskers highly innervated their mechanoceptors signal to primary somatosensory cortex, where column of neurons called “barrel” represents each them. This structure, known as barrel occupies large portion cortex rodent brain. Strikingly, Prdm1 conditional knockout mice one rare...