A5058104020- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Natural Antidiabetic Agents Studies
- Synthesis and biological activity
- Peptidase Inhibition and Analysis
- Computational Drug Discovery Methods
- Phytochemistry and biological activity of medicinal plants
- Chronic Lymphocytic Leukemia Research
- Soybean genetics and cultivation
- Nanoparticle-Based Drug Delivery
- Acne and Rosacea Treatments and Effects
- Chemistry and Chemical Engineering
- RNA Interference and Gene Delivery
- Ethnobotanical and Medicinal Plants Studies
- Retinoids in leukemia and cellular processes
- Phenothiazines and Benzothiazines Synthesis and Activities
- Multicomponent Synthesis of Heterocycles
- Crystal structures of chemical compounds
- Phytochemicals and Medicinal Plants
- Chromatography in Natural Products
- Phytochemical Studies and Bioactivities
- Advanced Drug Delivery Systems
- Metal complexes synthesis and properties
- Carbohydrate Chemistry and Synthesis
- Diverse Scientific Research Studies
Haldia Institute of Technology
2025
Central University of Rajasthan
2020-2024
Hindu College of Pharmacy
2019
JSS Academy of Higher Education and Research
2017-2018
With the aim of developing multidrug solids through a tuned crystal engineering approach, we have selected two antiurinary infective drugs, namely, nitrofurantoin (NF) and trimethoprim (TMP) isolated eight binary drug–drug solid solvates along with nonsolvated cocrystal. Crystal structure analyses were performed for these rationalized in terms known supramolecular synthons formed by pyrimidine, imide, amine functionalities. Notably, TMP–NF anhydrous cocrystal its ionic hydrate exhibit...
Due to changed lifestyle and other reasons, diabetes has become one of the common metabolic disorder globe. Numerous therapeutic options are available, which controls plasma glucose levels. However, most drugs associated with some undesired side effects. Owing effects enhanced understanding phytochemicals, an inclination toward herbal medicine is seen in population. These products also concerns like poor aqueous solubility, compromised permeation, a low degree bioavailability. So, emergence...
The ATP-dependent bacterial MurD enzyme catalyses the formation of peptide bond between cytoplasmic intermediate UDP-N-acetylmuramoyl-L-alanine and D-glutamic acid. This is essential for cell wall peptidoglycan synthesis in both Gram-positive Gram-negative bacteria. recognized as an important target development new antibacterial agents. In present study we prepared 3D-stucture catalytic pocket Staphylococcus aureus by homology modelling. Extra-precision docking, binding free energy...
The use of natural antimicrobial agents in surrounding area has achieved great importance the field pharmaceutical industry.This is due to challenge against microbes which causes pathogenic resistance by mishandling and misuse antibiotics.Now a day's many synthetic semi antibiotics are available lot side effect as well very expensive.So, alternative search from sources with minimum prompt safety quality products.Plant storage secondary metabolites plays crucial roles microbial...
Aims: To perform in-silico screening of the natural phytoconstituents against COVID-19 main protease Background: is an atypical virus that universal around globe. WHO (World Health Organization) has also affirmed emergency public health concerns regarding COVID-19. As spreads globally within a shorter duration, there great demand for effective therapy with minimal side effects. Objective: SP and XP docking naturally obtained ligand Quercetin (flavonoid) based on HTVS. : identify...
Ananas comosus (L) Merrill fruit is used for the treatment of urinary tract infection, and jaundice. The has anti-obesity activity as antihelmithic agent intestinal worms. contains many phytoconstituents; among them are Ferulic acid Chlorogenic exhibiting various pharmacological activities. To ensure content uniformity biomarkers, aim present study was to develop a HPTLC method simultaneous estimation in fruit. standard marker compounds four different extract solutions were applied on plate...
The cancer being the leading cause of death worldwide, breast is more common among all and effects around 25% women in world.The curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) which extracted from plant Cur¬cuma longa, exerts antiproliferative apoptotic effects.Curcumin possess high pleiotropic molecular property that interacts with its numerous targets.Curcumin G2/M arrest apoptosis, further inhibits cell proliferation by in¬hibiting assembly dynamics microtubules,...
The ovarian cancer is the fourth most leading cause for death in world.From ancient times metals are used treatment of many diseases Egypt and Greece, Ayurvedic medicine, Asian or by Aztecs elementary form.The synthesis compounds using combinatorial method helps formation several analogues a single synthetic route.Therefore we focused on Fe-SP method.We choose (Iron (III)-Salophene), an organometallic compound which shows selective cytotoxicity against SKOV-3 OVCAR-3 (ovarian epithelial...