A5044817973- Acute Ischemic Stroke Management
- EEG and Brain-Computer Interfaces
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Neural dynamics and brain function
- Neuroscience and Neural Engineering
- Voice and Speech Disorders
- Cardiac Arrest and Resuscitation
- Neurological Disorders and Treatments
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Advanced MRI Techniques and Applications
- Photoacoustic and Ultrasonic Imaging
- Optical Imaging and Spectroscopy Techniques
- Neonatal and fetal brain pathology
- Traumatic Brain Injury Research
- Traumatic Brain Injury and Neurovascular Disturbances
The University of Texas at Austin
2020-2022
Ascension
2022
Neurology, Inc
2020
Harvard University
2008-2011
Massachusetts Institute of Technology
2008
Johns Hopkins University
2002
A 10-hospital regional network transitioned to tenecteplase as the standard of care stroke thrombolytic in September 2019 because potential workflow advantages and reported noninferior clinical outcomes relative alteplase meta-analyses randomized trials. We assessed whether use routine practice reduced times with outcomes.We designed a prospective registry-based observational, sequential cohort comparison tenecteplase- (n=234) alteplase-treated (n=354) patients. hypothesized: (1) an increase...
Cortical compression can be a significant problem in many types of brain injuries, such as trauma, localized edema, hematoma, focal cerebral ischemia, or tumors. Mechanical and cellular alterations result global changes excitation inhibition on the neuronal network level even absence histologically cell injury, often manifesting clinically seizures. Despite importance prevalence this problem, however, precise electrophysiological effects injury have not been well characterized. In study,...
Summary Previous studies have shown that parameters of EEG restitution reflect the severity global hypoxic-ischemic brain injury. Here, hypothesis is tested patterns during first 4 hours predict later behavioral recovery. Time course and correlations between behavior, electrocorticogram (EcoG), neuronal injury were investigated in a rodent model asphyctic cardiac arrest. Forty Wistar rats subjected to 5 minutes asphyxia cardiopulmonary resuscitation. Behavior was assessed by repeated scoring...
Background: Our 10-hospital network (2 CSCs, 2PSCs, 6 non-SCs) switched our standard stroke thrombolytic from alteplase (ALT) to tenecteplase (TNK; 0.25 mg/kg) in September 2019. Methods: We designed a two-year prospective cohort analysis of key processes and clinical outcomes for TNK-treated patients with planned quarterly assessments feasibility safety. The TNK is compared the retrospective historical all unique at these hospitals treated ALT during prior 2-year period (n=354). Analysis...
Abstract Ischemic stroke is one of the leading causes death and disability in world. Recent advances acute care have dramatically improved clinicians’ abilities to reperfuse occluded blood vessels. With these advances, importance adjunctive therapies supplement or complement reperfusion therapy receiving greater interest. Cerebral collateral circulation such area that now gaining interest care. In this study, we investigate use peripheral electrical stimulation induce functional hyperemia a...
ABSTRACT Background and Purpose A 10-hospital regional network transitioned to tenecteplase as the standard of care stroke thrombolytic in September 2019 because its workflow advantages reported non-inferior clinical outcomes relative alteplase meta-analyses randomized trials. We assessed whether use routine practice reduces times with outcomes. Methods designed a prospective registry-based observational, sequential cohort comparison (n=234) (n=354) treated patients. hypothesized: (1) an...