do Nascimento, Junior P.; Koga, F. A.; Módolo, N. S.P.; Andrade, S.; Braz, L. G.; El Dib, R. Author Information

Keratoconjunctivitis sicca (KCS) is of predominantly immune-mediated origin. Dogs are an excellent model for understanding this disease, as the origin KCS in dogs like that humans. The objective study was to localize and quantify immunological markers, such CD4 lymphocytes, interleukin (IL)-1, IL-6 tumor necrosis factor alpha (TNFα), before after topical treatment with mesenchymal stem cells (MSCs). Twenty-two positive were topically treated 50 μL (1 × 106 MSCs) conjunctival sac evaluated 6...

It is called fecaloma when the stool retained and resected inside colon.The patient may present clinical signs such as difficulty in defecating, vomiting, constipation, apathy, tenesmus hematochezia.They occur with greater incidence felines due to their behavioral hygiene habits, mainly by ingestion of hairs also refusal defecation finding dirty place.Another triggering factor low water intake.This study aims report case a severe fecal impaction male feline, mixed breed, black coat, four...

The transmissible venereal tumor (TVT) is a contagious neoplasm of round cells that frequently affect dogs.The treatment consists chemotherapy being more effective the vincristine alone, however resistance emergence to this agent due multidrug P-glycoprotein (P-gp), transporter protein encoded by MDR1 gene, has been taking association with other drugs.Recent studies demonstrated antitumoral effect avermectins when associated in some neoplasms.Therefore, objective present study was compare...

To compare the accuracy between two applanation tonometers, Tono-Pen XL(®) and Perkins(®), in ophthalmoscopically normal dogs cats.Both eyes of 25 conscious healthy cats were evaluated. Both five immediately after sacrifice used as controls for postmortem study.In animals, tonometry was performed with topical anesthesia using 0.5% proxymetacaine eye drops both tonometers 1% fluorescein Perkins tonometer. Readings intraocular pressure (IOP) study taken manometry by Perkins(®).The correlation...

To compare strip meniscometry and Schirmer tear test 1 results film breakup time between dogs with normal eyes diagnosed keratoconjunctivitis sicca. Methods: One-hundred fifty-six of 78 dogs, 88 eyes, 68 sicca were included in the study. The tests performed following sequence: was used to allocate or group, followed by measurement.The (mean ± standard deviation) group as follows: 1, 22.75 3.88 mm/min; test, 10.01 2.35 mm/5 sec; time, 25.82 5.47 sec. In 6.10 4.44 3.03 2.62 10.78 4.23 Spearman...

Background and Aim: Tonometers are an important instrument for measuring intraocular pressure (IOP) in the diagnosis of glaucoma or uveitis. This study aimed to compare accuracy main types tonometers with different IOP measurement methodologies dogs: TonoVet Plus (rebound), Tono-Pen Avia Vet (applanation), Kowa HA-2 (Goldmann applanation). Materials Methods: was measured 152 eyes 76 dogs. A postmortem performed by comparing manometry tonometry values calculating correlation coefficient (r2),...

The objective of this study was to evaluate and validate the accuracy Perkins handheld applanation tonometer for measuring intraocular pressure (IOP) in horses cattle. Both eyes 10 adult cattle were evaluated a postmortem study. from clinically normal also examined after bilateral auriculopalpebral nerve block topical anesthesia an vivo IOP measured using direct manometry (measured with aneroid manometer) tonometry tonometer). correlation coefficients (r(2)) data 0.866 0.864 In study, 25.1 ±...

Measurement of the intraocular pressure (IOP) is a useful diagnostic tool in equine ophthalmology. Handheld tonometers, such as Tonovet and Plus (rebound), Tono-Pen AVIA Vet (applanation), Kowa HA-2 (applanation using Goldmann methodology) are used to obtain IOP measurements veterinary medicine.To compare evaluate accuracy four handheld tonometers measuring different methodologies healthy horses.In vivo experiment cross-sectional survey horses.Intraocular was measured 72 eyes 36 horses. An...

The objective of this study was to evaluate the effectiveness various linseed oil (LO) preparations (oral, topical, oral and topical combined) in treating experimentally induced keratoconjunctivitis sicca (KCS) rabbits. Twenty male New Zealand white rabbits were divided into four groups: group C (control), OLO (oral LO), TLO (topical OTLO LO). animals evaluated weekly using Schirmer's tear test (STT), fluorescein (FT), Rose Bengal (RBT) euthanized at end experiment for histopathological...

To compare the efficacy of 0.03% to pical tacrolimus in combination with oral omega (ω) 3 different ratios eicosapentaenoic acid (EPA), docosahexaenoic (DHA), and antioxidants as adjuvant treatment keratoconjunctivitis sicca (KCS) dogs.Methods: Forty-five dogs KCS were evaluated monthly for 6 months.Evaluations included performance Schirmer tear, fluorescein, lissamine green tests.Tear film break-up time (TBUT) was assessed.Conjunctival cytology at beginning, middle, end study.Conjunctiva...

Purpose: To evaluate the effectiveness of topical 1% cyclosporine eye drops diluted in either two vehicles-olive and linseed oil-and that oils themselves treating experimentally-induced keratoconjunctivitis sicca (KCS) rabbits. Methods: KCS was induced 25 New Zealand rabbits using atropine sulfate for 7 days before treatment throughout period (12 weeks). The were divided into five groups: one control (C) group without induction four groups which treated topically with olive oil (O), (L),...

Abstract Objective To evaluate and to validate the accuracy of Perkins ® handheld applanation tonometer in measurement IOP dogs cats. Animals Twenty eyes from 10 cats immediately after sacrifice were used for postmortem study 20 clinically normal anesthetized vivo study. Both conscious also evaluated. Procedure Readings taken using manometry (measured with a mercury column manometer) tonometry tonometer). The was accomplished by instillation proxymetacaine 0.5% 1% fluorescein eye drops....

Objective: To compare the efficacy of 0.03% tacrolimus eye drops diluted in two different vehicles (linseed oil and olive oil) for treatment keratoconjunctivitis sicca (KCS) dogs.Methods: This study included 60 dogs.Of this group, 20 were healthy allocated to control 40 diagnosed with bilateral KCS randomly either TO (tacrolimus or TL linseed groups.Ophthalmic examinations, Schirmer Tear Test-1 (STT-1), Film Break-up Time (TBUT) Fluorescein Test (FT) carried out monthly, along cytological...

The objective of this study was to compare the accuracy between two applanation tonometers, Tono-Pen XL® and Perkins®, in horses cattle. eyes 20 cattle conscious healthy were evaluated for vivo both 5 used as controls postmortem study. In animals, tonometry performed with auriculopalpebral nerve block then topical anesthesia tonometers 1% fluorescein eye drops only Perkins tonometer. Readings intraocular pressure (IOP) taken using manometry by Perkins®. correlation coefficient (r²) horses,...

Abstract Resveratrol has antioxidant, anti-inflammatory, lipolytic, and antifibrotic properties, which may be useful in supplementation of obese patients with liver problems. This study evaluated the effects 6-week resveratrol on lipid profile function female Wistar rats fed a high-fat diet to induce obesity. Sixty-four were divided into 4 groups (n = 16): control group (C); (CO); (R); (RO). At end experiment, animals anesthetized for blood collection subsequent euthanasia biopsy. The...

This work studied the effects of experimental amitraz intoxication in cats. Sixteen cats were randomly divided equally into two groups: group - animals received 1.5% at 1mg/kg IV; and control without amitraz. Physiological parameters from blood, cardiorespiratory system, sedation indicators quantified over time up to 360 minutes. Blood profile, urea, creatinine, alananine aminotransferase aspartate not affected by Sedation, loss reflexes, hypothermia, bradycardia, bradyarrhythmia,...

The objective of this study was to compare the efficacy two sources omega 3 and 6, fish oil (FO) linseed (LO), orally administered, alone or in combination, for treating experimentally induced keratoconjunctivitis sicca (KCS) rabbits. Twenty-eight New Zealand rabbits were used study. Seven animals allocated C group (negative control), KCS 21 by topically applying 1% atropine sulfate drops 7 days. Treatment with maintained throughout period (12 weeks). divided into treatment groups containing...

The objective of this study was to evaluate the use Kowa HA-2 applanation tonometer in measuring intraocular pressure (IOP) dogs. Twenty eyes were used an ex vivo which calibration curve for manometry vs. tonometry determined by artificially raising IOP 5 mmHg increments up 60 (10-60 mmHg). Both 10 anesthetized dogs studied compare tonometry. In ambulatory study, 168 healthy eyes, 74 with glaucoma and uveitis evaluated tonometry, performed topical anesthesia 1% fluorescein eye drops...

SUMMARY This study compared the effectiveness of either yohimbine or atipamezole in reversion hyperglycemia and blood gas alterations induced by Triatox ® . Thirty dogs were equally divided into 3 groups (T, TY, TA). Group T was given 2.5% i.v. at 1 mg/kg; TY received same dose followed 0.1 mg/kg (2 mg/mL) 30 minutes later; TA 0.2 (5 later. Blood samples every animal drawn to measure plasma glucose concentration gases 0, 30, 60, 120 360 after amitraz administration. Hyperglycemia observed...

ABSTRACT: The objective of this study was to evaluate the antimicrobial susceptibility profile bacteria isolated from eyes dogs with keratoconjunctivitis sicca (KCS). We evaluated 65 diagnosed KCS and 30 healthy (Control Group). Conjunctival swab samples were collected after diagnosed. Microbiological examinations performed, including aerobic culture, testing minimum inhibitory concentration (MIC) determination for chloramphenicol, tobramycin, ofloxacin moxifloxacin. MICs fifteen most...