About
Contact & Profiles
A5094068131
Research Areas
- Cell Adhesion Molecules Research
- Angiogenesis and VEGF in Cancer
- Cancer, Hypoxia, and Metabolism
Uppsala University
2024
Compromised vascular integrity facilitates extravasation of cancer cells and promotes metastatic dissemination. CD93 has emerged as a target for anti-angiogenic therapy, but its importance in cancers not been evaluated. Here, we demonstrate that participates maintaining the endothelial barrier reducing Primary melanoma growth was hampered CD93-/- mice dissemination increased, associated with disruption adherens tight junctions tumor elevated expression matrix metalloprotease 9 (MMP9) at...
10.1172/jci.insight.169830
article
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JCI Insight
2024-03-05
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