Environmental and climatic factors have a significant impact on the immune system, shaping its composition functions. The semiarid region of Aleppo, characterized by hot, dry summers moderate, wet cold winters, is also environmental pollution such as air pollutants industrial chemicals. interaction these can impair function causing inflammatory responses, compromising integrity cells, impairing body’s ability to mount an effective response. To date, physiological characteristics parameters...

Background . T cell immunity is known to play a central role in controlling SARSCoV- 2 (severe acute respiratory syndrome-related coronavirus 2) infection, so it critical understand its recovery from COVID-19 (coronavirus disease 2019), especially the unfavorable conditions of North.The aim. To assess immune status women after living subarctic region Russian Federation. Materials and methods We examined total 50 aged 36–46 years, including 38 vaccinated 6 12 months (control group) who had...

The extreme climate and eco-environment of the Russian subarctic region hamper processes self-regulation re-establishment optimal functioning body systems. This leads to activation stressing cell humoral mechanisms immunity disruption immune homeostasis. Vascular endothelium growth factor (EGF) is key for system as it influences substantially blood-forming differentiation. fact that VEGF concentration rises during COVID-19 impacts its pathogenesis can be used a prognostic indicator severity....

Rotational shift work in the Arctic region's northern seas has a substantial influence on physiological condition of human body and high risk reducing reserve capacities, particularly immune system. Assessing homeostasis by identifying balance, specifically levels expression lymphoproliferation lymphoapoptosis markers that determine body's susceptibility to diseases, is important for maintaining public health extreme climatic professional environments. The aim this study assess ratio...

Phenotypic features of human immune homeostasis in different climatic and geographical regions are determined by the characteristic formation an adaptive response changing environmental conditions. The purpose work — identification variants using multidimensional statistical analysis people working age living extreme climate North-Western Mountain-Southern regions. Materials methods. results survey 164 aged 20-60 years, residents region were analyzed: men 38,42% (63 people), women – 61,59%...

The climate and environment of the northern central regions Russia have a significant impact on human health and, particularly, immune system, especially in women. Exposed to adverse conditions, status is characterized by short period resistance, deficiency T-cell population, weakened reserve capacity homeostasis, increased incidence disorders. A study has been conducted identify ratio differentiated T-cells response healthy, working women aged 40–60, residing settlement Pinega (Arkhangelsk...

Abstract The human body in adverse living conditions, such as the Arctic, goes through risk of impairing functional systems including immune system. These disturbances lead to appear states weakness or hyperactivity organism protective function. This study investigates state adaptive response 40-60-year-old women Russian Arctic and South Ossetia. indirect immunoperoxidase assay with monoclonal antibodies was used analyze parameters lymphoid subpopulations Nadym city Yamalo-Nenets Autonomous...

Sustainable development of Russian Arctic territories requires creating favourable living conditions and preserving public health. Living in high latitudes, one is exposed to adverse environmental factors, which can lead changes the activity life functions, including immune response. The study lymphoid population ratio allows us reveal age-related formation adaptive response women born North, especially important given increasing retirement age. purpose this work was determine populations...

The immune system is a complex human mechanism that performs wide range of effector functions, as well powerful and not yet well-understood regulatory processes are involved in its activities. Phagocytosis one the oldest defense mechanisms (paleoimmunity). More evolutionarily young cellular immunity (neoimmunity). T-lymphocytes mature thymus divided into: T-suppressors, T-killers, T-helpers differ function surface antigens. Domestic foreign authors indicate Ts cells play large role...

Introduction: Climatic factors are important determinants of human health acting through different mechanisms including the immune system. Long-term exposure to extreme climatic conditions may result in response disturbances manifested by secondary immunodeficiency. Aim: To assess concentration T-helpers peripheral blood (CD4+) men living North and South. Methods: Altogether, 32 aged from 20 60 years Arkhangelsk (Arctic Russia) 30 same age Aleppo (Syria) comprised sample. The analysis...