A5040129059- Structural Load-Bearing Analysis
- Structural Analysis and Optimization
- Composite Structure Analysis and Optimization
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Mechanical stress and fatigue analysis
- Hepatitis C virus research
- Structural Behavior of Reinforced Concrete
- Structural Engineering and Vibration Analysis
- Topology Optimization in Engineering
- Structural Engineering and Materials Analysis
- Medical Imaging and Pathology Studies
- Liver Disease Diagnosis and Treatment
- Metal Forming Simulation Techniques
- Systemic Lupus Erythematosus Research
- Engineering Structural Analysis Methods
- Evacuation and Crowd Dynamics
- Laser and Thermal Forming Techniques
- Wind and Air Flow Studies
- Cardiac Structural Anomalies and Repair
- Fire effects on concrete materials
- Drug-Induced Hepatotoxicity and Protection
- Acute Myocardial Infarction Research
- Occupational Health and Performance
- Systemic Sclerosis and Related Diseases
- Urban Design and Spatial Analysis
Universidad de Navarra
2009-2024
Universidad Publica de Navarra
2020
Clinica Universidad de Navarra
1993-2018
Hospital General Universitario Morales Meseguer
2004
Hepatitis C virus (HCV) is an RNA that replicates in both the liver and lymphoid cells. Interferon-α (IFN-α) a useful treatment of chronic hepatitis (CHC) although resistance to this drug occurs frequently. The mechanisms underlying IFN remain unknown. In work, we have measured levels glutathione plasma peripheral cells from 15 healthy controls 24 CHC patients, 10 whom were without 14 showed high serum alanine aminotransferase (ALT) values despite therapy with lymphoblastoid for more than 4...
We investigated the presence of positive (genomic) and negative (replicative intermediate) hepatitis C virus RNA strands in liver, peripheral mononuclear cells serum from patients with chronic using a selective semiquantitative polymerase chain reaction procedure. Negative were present lymphoid all untreated those who did not respond to interferon therapy. In latter group patients, titers liver at end treatment similar encountered but about 100 times lower than pretreatment values. responded...
The objective of this research is to study an alternative conventional moment-resisting beam-to-column steel joints through the design optimised connections made by additive manufacturing using steel. proposed intended fulfil criteria such as following: connection has be moment-resistant, and different structural elements should join easily possible, enabling them attached detached consequently allowing reuse achieved application Structural Topological Optimisation tools from software TOSCA,...
A study of axial–moment interactions bolted connections with double extended end plates is presented in this paper. Six connections, subjected to pure compression and flexural were tested for purpose. After the experimental campaign, finite element models developed calibrated accurately reproduce results. The included initial imperfections capture possible buckling failure modes column web beam flanges. Moreover, without compared different sizes imperfection. Finally, results obtained from...
The use of composite semi-rigid connections is not fully exploited, in spite its great number advantages. Composite may lead to an optimal moment distribution that will render lighter structures. Furthermore, using the appropriate connection design, stability frames against lateral loads entirely rely on joint stiffness, thus avoiding bracing systems and permitting more diaphanous designs. Although modern codes, such as Eurocode 4 (EC4), propose thorough methods analysis they do provide...
El dimensionado de las escaleras en caso incendio se encuentra entre características más importantes del diseño arquitectónico actual. La mayor complejidad los edificios (usos mixtos, espacios con alta ocupación, personas discapacidad, altura, etc.) suma a nuevos hábitos sociales, y actividades que desarrollaban tradicionalmente partes bajas edificios, tienden ocupar pisos altos. Este artículo muestra cálculos prescriptivos para el protegidas son incapaces enfrentarse este reto por estar...
<b>Background:</b> Interstitial lung disease (ILD), is the main cause of mortality in Idiopathic inflammatory myopathy (IIM). Epidemiological, prognostic and treatment information are scarce. The goal was to characterize a cohort IIM patients compare response immunosuppression (IS) among different types IIM. <b>Methods:</b> Observational, multi-centric study 30 centers from Argentina Uruguay. <b>Outcomes:</b> Response IS defined as worsening: decline FVC >10%; improvement: increase...
Abstract This research deals with the axial‐bending interaction in bolted steel beam to column connections along strong axis of column. In order define curves, firstly, a series tests doubly symmetric were carried out which two sizes considered, while beam, end plate and bolts remained same. These joints tested under pure compression, as well simultaneous bending different load levels. Afterwards, reduced finite element models including initial imperfections made. are validated by means...