A5031109271- Neonatal Respiratory Health Research
- Neuroscience of respiration and sleep
- Infant Development and Preterm Care
- Maternal and Neonatal Healthcare
- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- Infant Nutrition and Health
- Breastfeeding Practices and Influences
- Patient Safety and Medication Errors
- Congenital Heart Disease Studies
- Neonatal Health and Biochemistry
- Pregnancy and preeclampsia studies
- Neonatal and Maternal Infections
- Psychology and Mental Health
- Airway Management and Intubation Techniques
- Cardiovascular Conditions and Treatments
- Healthcare Technology and Patient Monitoring
- Methemoglobinemia and Tumor Lysis Syndrome
- Birth, Development, and Health
- Pulmonary Hypertension Research and Treatments
- Tracheal and airway disorders
- Preterm Birth and Chorioamnionitis
- Obstructive Sleep Apnea Research
- Phonocardiography and Auscultation Techniques
- Nursing care and research
Universidade Federal de São Paulo
2021-2023
Hospital Infantil de México Federico Gómez
2020
Instituto Nacional de Saúde
2020
Fundação Oswaldo Cruz
2001-2018
Universidade Estadual Paulista (Unesp)
1985-2016
Hospital General Universitario Gregorio Marañón
2016
King's College London
2016
Tampere University
2016
Tampere University Hospital
2016
University of Toronto
2004
The caudocephalad profile of esophageal pressure swings was studied in 10 preterm and 5 full-term infants, the effect chest wall distortion on analyzed 12 infants. Esophageal measured with a fluid-filled catheter, tidal volume pneumotachograph, mouth face mask transducer, rib cage abdominal motion magnetometers. In infants fell very steeply direction. it flat during quiet sleep steep rapid-eye-movement sleep. When breaths, standardized for pleural pressure, were compared between period...
We studied the effect of caffeine on voluntary and electrically stimulated contractions adductor pollicis muscle in five adult volunteers. Caffeine (500 mg) was administered orally a double-blind fashion. Electrical stimulation ulnar nerve performed at 10, 20, 30, 50, 100 Hz before after sustained contraction held 50% maximal (MVC). A brief tetanus 30 also to calculate relaxation rate fresh muscle. Contractile properties, rate, endurance were then assessed placebo, as well response fatigued...
The importance of inspiratory muscle tone in the maintenance functional residual capacity (FRC) newborns was studied eight premature infants with birth weights 1,166 +/- 217 g and gestational age 29 1.9 wk (mean SD). Rib cage abdominal anteroposterior diameters were monitored magnetometers, electromyograms diaphragm intercostal muscles recorded surface electrodes. Sleep state using electrooculogram behavioral criteria. We assessed decrease tonic activity fall end-expiratory lung volume...
Objective To verify whether the use of T-piece resuscitator compared with self-inflating bag in preterm infants ventilated at birth modifies survival to hospital discharge without major morbidities. Design Pragmatic prospective cohort study. Setting 20 Brazilian university hospitals Network on Neonatal Research. Patients were 1962 inborn 2014–2015 23–33’ weeks gestation and weight 400–1499 g malformations. transferred until 27th day after excluded. Interventions Positive pressure ventilation...
OBJETIVO: Avaliar os fatores perinatais associados ao óbito neonatal precoce em prematuros com peso nascer entre 400 e 1.500 g. MÉTODOS: Coorte prospectiva multicêntrica dos nascidos vivos idade gestacional de 23 a 33 semanas 400-1.500 g, sem malformações oito maternidades públicas terciárias universitárias junho 2004 maio 2005. As características maternas neonatais morbidade nas primeiras 72 horas vida foram comparadas que morreram ou sobreviveram até o sexto dia vida. variáveis associadas...
We studied diaphragmatic and intercostal muscle activity the pattern of motion rib cage abdomen after fatigue in 15 newborn infants (birth wt 1,251 +/- 424 g, mean SD). Rib abdominal were monitored with magnetometers electromyograms (EMG's) surface electrodes. Twelve showed a total 66 episodes identified by EMG frequency spectrum analysis. Two patterns responses to observed. In first case, five consistently recruited their muscles; this was followed normalization spectrum. these infants,...
Background: Late-onset sepsis (LOS) is an important cause of morbidity and mortality in very low birth weight (VLBW) infants.
Introduction. Respiratory distress are very common in Very-low-birth-weight (VLBW) infants and Myocardial injury may play a role the disease outcome. Cardiac troponin T (cTnT) is most useful marker of adult population, but has not been extensively studied this population. Aim. To study cTnT VLBW its association with clinical outcomes. Methods. All admitted to our NICU were included study. Echocardiography blood samples for determination collected at 24 48 hours life, values >0.1 ng/mL...
There have been dramatic increases in very low birth weight infant survival. However, respiratory morbidity remains problematic. The aim here was to verify associations between pulmonary mechanics, structural abnormalities and during the first year of life.
We studied the effect of chest wall distortion (CWD) on transdiaphragmatic pressure (Pdi) and/or mouth during end-expiratory airway occlusions in seven preterm infants. measured occlusion (Pmo) with a face mask and transducer, gastric (Pga) fluid-filled catheter, diaphragmatic electromyogram (Edi) using surface electrodes, rib cage abdominal motion magnetometers. reasoned that Pdi = Pmo - Pga occlusion. Periods maximal periods minimal CWD were compared. found 1) when was minimal, an increase...
Premature infant lung development may be affected by injuries during the first few weeks of life. Lung have been associated with changes in mechanics.
OBJETIVO: Verificar a incidência de morbidade respiratória no primeiro ano vida prematuros muito baixo peso e verificar se existe diferença na segundo os fatores risco neonatais. MÉTODOS: O desenho foi coorte prospectivo. Foram estudados neonatos com nascimento inferior 1.500 g idade gestacional 34 semanas nascidos entre 1998 2000. As crianças foram acompanhadas mensalmente Ambulatório Seguimento até 12 meses corrigida para prematuridade. A cada consulta, verificada presença síndrome...
<h3>SUMMARY:</h3> Since 2005, it has been known that mother-to-child transmission of the chikungunya virus is possible. Transmission generally occurs in perinatal period. In present study, we describe brain lesions seen on MR imaging 6 cases infection. Patients who underwent acute phase presented with areas restricted diffusion white matter, suggesting a perivascular distribution, whereas those subacute/late showed cystic lesions, also or without atrophy. One patient scattered hemorrhages...
ABSTRACT The causative factors of neonatal feeding intolerance are poorly understood, but potentially related to clinical practices such as empiric antibiotic usage. objective this study was evaluate whether early exposure negatively affects preterm infants’ enteral tolerance. Data from infants without risk for sepsis, 500 1499 g birth weight and 24 34 weeks gestational age were analyzed. primary outcomes the effects on total parenteral nutrition usage duration prevalence necrotizing...
BACKGROUND AND OBJECTIVES Despite being preventable, neonatal hypothermia remains common. We hypothesized that the proportion of newborns with on admission would be high in all settings, higher hospitals middle-income countries (MIC) compared high-income (HIC), and associated morbidity mortality. METHODS Using Vermont Oxford Network database birth weights 401 to 1500 g or 22 29 weeks’ gestational age from 2018 2021, we analyzed maternal infant characteristics, delivery room management,...
Objective To evaluate the temporal trend of bronchopulmonary dysplasia (BPD) in preterm infants who survived to at least 36 weeks’ post-menstrual age (PMA) and BPD or death PMA, analyse variables associated with both outcomes. Design Retrospective cohort data retrieved from an ongoing national registry. Setting 19 Brazilian university public hospitals. Patients Infants born between 2010 2019 23–31 weeks birth weight 400–1499 g. Main outcome measures Temporal was evaluated by Prais-Winsten...