Background: This study evaluated the combined effects of oxylanthanum carbonate (OLC), an investigational phosphate binder, and tenapanor, approved sodium/hydrogen exchanger 3 (NHE3) inhibitor that reduces paracellular absorption, on urinary excretion in rats a high phosphorus diet. Methods: Sixty-four male Sprague Dawley were randomized into eight groups: vehicle; tenapanor (0.15 mg/kg) only; OLC (0.75%, 1.5%, 3%) combination + mg/kg). Vehicle dosed orally twice/day whereas was incorporated...

Background: Laparoscopic cholecystectomy (LC) has become the gold standard treatment for gallstone disease. Though mostly safe occasionally it can be difficult due to various problems faced during surgical procedure. Anticipation of likely difficulty help in avoiding complications.Methods: With aim identifying predictors and their correlation with this prospective study on 50 adults undergoing laparoscopic symptomatic cholelithiasis was undertaken. Various clinical, radiological biochemical...

Laparoscopic cholecystectomy is the gold standard procedure for cholelithiasis. Pneumoperitoneum created using carbon dioxide (CO2) which usually maintained at a range of 12-14 mm Hg. An emerging trend has been use low-pressure pneumoperitoneum in 7-10 Hg an attempt to lower impact on human physiology while providing adequate working space. Our study proposes compare effects with pressure pneumoperitoneum.To and analyze various factors like blood pressure, heart rate, end-tidal CO2...

ABSTRACT India is a high-incidence area for gallbladder cancer (GBC), contributing approximately 10% of the global GBC burden. Within country, incidence notably high in North, North-East, Central, and Eastern regions, whereas it less common South West India. The has been steadily rising both genders. Patients often present with advanced disease, which carries dismal prognosis. Unlike West, typically affects younger patients their fifth sixth decades life. Gallstones are 80% Indian patients,...

Objective:Various ventral and incisional hernia repair techniques exist have largely replaced the open ones. The purpose of this study was to document 2-port technique demonstrate that it is feasible, efficient, safe. To our knowledge, largest report on topic date in English-language literature.Methods:Forty patients with hernias (VH) or (IH) underwent laparoscopic a technique. involves insertion one 10-mm 12-mm balloon port 5-mm port, usually left side as laterally possible. A mesh inserted...

ABSTRACT Porcelain gallbladder or calcified is a rare entity and considered as the end stage of chronic cholecystitis. This disease rarely diagnosed preoperatively usually mimics carcinoma gallbladder. Hereby, we present interesting case porcelain that was managed by cholecystectomy. How to cite this article Goel A, Agarwal Gupta S, Bhagat TS, Kumar G, AK. Gallbladder. Euroasian J Hepato-Gastroenterol 2017;7(2):181-182.

The insecticidal activity of essential oils obtained from DCM extracts Psoralea corylifolia (Fabaceae) against pupa Epilachna insect was investigated in a series laboratory experiments. Insecticidal determined at 24 ± 4°C and 68 5% R.H., dark conditions. the dried seeds plants were subjected to Column chromatography oil then hydrodistillation using Clevenger type apparatus. major components these are identified GC-MS spectroscopy their tested. predominant toluene, alpha-pinene,...

Cellulitis is a bacterial infection of the dermis and subcutaneous tissues occupying large proportion hospital beds. This study was conducted for analysis patients with cellulitis according to their demographics clinical presentation examine comorbidities, complications, its management. observational cross-sectional in Department Surgery at Santosh Medical College Hospitals involving total 60 cases having other soft tissue infections lower limb. Analysis demographic profile, management,...

ABSTRACT Breast cancer remains one of the most prevalent and impactful malignancies affecting women globally. This review article aims to provide a comprehensive overview epidemiology, risk factors, screening methods, diagnostic procedures, treatment options, recent advances in breast management. Drawing from wide range sources, including authoritative textbooks, peer-reviewed journals, guidelines leading health organizations, this synthesizes current knowledge highlights areas for future...

Abstract Introduction Though the incidence of gender-affirming surgery (GAS) is increasing within United States (US), many transgender and gender diverse individuals are denied insurance coverage for these procedures. Some turn to crowdfunding financial assistance. Objective We aimed determine characteristics fundraisers genital GAS US factors associated with greater funding. Methods GoFundMe largest individual platform in was queried January 2023 using search terms related such as “bottom...

Aim and Objectives: The present study compared the outcome of diathermy versus scalpel skin incision in surgical cases. Materials Method: Prospective interventional was done at Santosh Medical College & Hospital for a period 1.5 years. Group A included 100 patients treated with Scalpel B Diathermy. Results: mean Incision time (s), (s/cm 2 ) Pain VRS score day 1 significantly more among group to Diathermy group. Blood loss (ml) Conclusion: Due shorter times, less blood loss, early...

Since its sudden outbreak in December 2019 Wuhan, A pandemic of SARS-CoV-2 has been announced. Vitamin C is a water-soluble vitamin with anti-oxidant and immunity-boosting properties. acts as nutritional supplement profoundly impacting the immune response to second or third wave coronavirus disease (COVID-19). efficacy an adjuvant treatment for inflammation symptoms associated COVID-19 infection should be investigated further. This report sheds light on available information current clinical...

Background: Conventional open appendicectomy is a common emergency surgical procedure being used for more than century. Despite continuously increasing popularity of minimal access surgery, laparoscopic has not gained enough popularity.Methods: A prospective randomized study to compare and the treatment appendicitis was carried out from April 2015 October 2016. Thirty patients each were two groups. Decision operate taken on clinical grounds.Results: Twenty-five in group confirmed be...

Introduction: Fistula in ano is a common anorectal disorder requiring surgical intervention. It associated with high recurrence rate and post-operative complications. In this study we have analysed compare results of newer technique for low anal fistula SLOFT conventional Fistulectomy. Aims Objective: To Submucosal Ligation Tract (SLOFT) fistulectomy patients by analysing various intra-operative factors outcome. Materials Methods: An interventional carried out at Santosh Medical College...

Haemorrhoid is a common anorectal disorder which usually requires surgical intervention. Conventional haemorrhoidectomy had been practiced for long time but in 1993 Longo introduced newer minimally invasive procedure haemorrhoids. In this study we have compared the post-operative results of MIPH with conventional open haemorrhoidectomy. To analyze and compare various Pre factors such as duration surgery, pain analgesia, hospital stay, post- operative complications, recurrence early return to...

Introduction: Effectiveness of tamsulosin in distal urolithiasis, which provide drastically comfort to the patient, considering stone expulsion, renal colic, expulsion time and costs. Aim: To evaluate efficacy ureteral stones determine rate time. Materials Methods: An interventional study was conducted department surgery, Santosh Medical College Hospital, Ghaziabad. 100 patients were included from 15–45 years age both sexes having a single unilateral 2–8 mm size. Patients multiple or...