Solvent‐free oxidative synthesis of benzimidazoles, benzoxazoles and benzothiazoles from aromatic alcohols o ‐phenylenediamine, ‐aminophenol ‐aminothiophenol has been achieved by using CuCl, 2,2′‐bipyridine TEMPO (2,2,6,6‐tetramethylpiperidine‐1‐oxyl). The reaction proceeds via a dehydrogenation in open air at room temperature, wide variety derivatives were obtained good to excellent yields. mechanism was proposed this method provides mild efficient access substituted benzothiazoles....

Abstract Solvent-free oxidative synthesis of benzimidazoles, benzoxazoles, and benzothiazoles from aromatic primary amines o-phenylenediamine, o-aminophenol, o-aminothiophenol has been achieved by using Fe(NO3)3 TEMPO (2,2,6,6-tetramethyl-1-piperidinyloxyl). This reaction can use air as an economical green oxidant, a wide variety derivatives were obtained in good to excellent yields. The mechanism was proposed this method provides direct, practical, efficient approach for the preparation...

A simple and efficient catalytic system for direct conversion of methylarenes into aromatic oximes has been developed, with Cu(OAc)2 as catalyst, NHPI (N-Hydroxyphthalimide) additive, TBN (tert-butyl nitrite) both the nitrogen source oxidant. This process proceeds under mild conditions, tolerates a wide range substrates, affording targeted in 63-86% yields.

Abstract A simple and efficient catalytic system for the aerobic oxidation of primary amines into corresponding oximes has been developed, with 3‐methyl‐4‐oxa‐5‐azahomoadamantane as catalyst, acetaldoxime co‐catalyst water solvent. This process, which uses oxygen (O 2 ) an economic green oxidant a solvent, tolerates wide range substrates, affording target in moderate to excellent yields. It was found that high selectivity achieved when used, E ‐type were only detected products. possible...

Abstract Solvent-free oxidative synthesis of benzimidazoles from arylmethylamines and o-phenylenediamine has been achieved under catalyst-free conditions. This reaction can use tert-butyl hydroperoxide (TBHP) as the oxidant, a wide variety derivatives were obtained in good yields. The mechanism was proposed this method provides direct practical approach for preparation substituted benzimidazoles.

Jiatao Yua* & Ming Luaa Nanjing University of Science and Technology, Chemical Engineering College, Nanjing, China

Abstract Shutdown operations in olefin plants generate extensive flare emissions, which cause adverse environmental and societal impacts as well large amounts of raw material energy losses that could supposedly be unitized to much more needed products. Consequently, shutdown optimization for minimization is crucially important all stake holders. However, the current practice almost exclusively depends on experienced operators, engineers, plant administration. There still a lack systematic...

A general, efficient, and metal-free method for aerobic oxidation of aromatic primary amines to the corresponding oximes catalyzed by <i>N</i>,<i>N</i>′,<i>N</i>″-trihydroxyisocyanuric acid acetaldoxime with water as solvent is described. This practical can use air economic green oxidant, solvent, tolerates a wide range substrates, which afford target in moderate good yields.

A novel and highly efficient copper‐catalyzed intramolecular cyclization reaction of 2‐iodoanilines with nitriles for the synthesis benzimidazoles l ‐proline as ligand has been developed. variety substituted benzimidazole derivatives can be synthesized high yields using this approach. Copyright © 2014 John Wiley &amp; Sons, Ltd.

Abstract The application of [C 12 mim]Br ionic liquid/o‐xylene temperature‐dependent biphasic system into the [Imim‐TEMPO][Cl]/O 2 ‐promoted condensation between o ‐phenylenediamines, ‐aminophenol or ‐aminothiophenol with aldehydes for preparing benzimidazoles, benzoxazoles benzothiozoles is described. Several and were reacted efficiently to form corresponding products in excellent yields. Both [Imim‐TEMPO][Cl] could be reused at least eight times without significantly decreasing catalytic activity.

In this paper, Iron(III)-catalyzed aerobic oxidation of imine derivatives and o-phenylenediamine under air condition is studied in detail.With Fe(NO 3 ) •9H 2 O as catalyst green economical oxidant, the reaction could take place acetonitrile at 80 ℃ affords benzimidazoles target compounds good yields after 10 h, exhibiting application prospect well.This process includes three steps: (1) oxidative condensation to form Schiff base, (2) formation benzimidazoline via nucleophilic addition Shift...

Abstract 1‐Dodecyl‐3‐methylimidazolium bromide (DMIB) acts both as an ionic liquid solvent and phase transfer catalyst well in the biphasic system with o‐xylene.

Abstract In contrast to aromatic or alkenyl substituted primary oximes, aliphatic oximes are inaccessible using this method.

Abstract Variously substituted methylarenes, including sterically hindered ones, as well methylhetarylarenes are efficiently transformed to aromatic oximes.

Abstract This green and selective oxidation of amines gives E‐type oximes in high yields.