A5054731352- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Animal Genetics and Reproduction
- Effects of Environmental Stressors on Livestock
- Human-Animal Interaction Studies
- Cardiovascular Conditions and Treatments
- Milk Quality and Mastitis in Dairy Cows
- Congenital heart defects research
- Animal Nutrition and Health
- melanin and skin pigmentation
- Cancer-related molecular mechanisms research
- Mineral Processing and Grinding
- Agriculture and Biological Studies
- Reproductive Physiology in Livestock
- Genetic diversity and population structure
- Cardiac Valve Diseases and Treatments
- Wnt/β-catenin signaling in development and cancer
- Climate Change and Health Impacts
- Nuts composition and effects
- Congenital Heart Disease Studies
- Animal Diversity and Health Studies
- Animal Behavior and Welfare Studies
- Research in Cotton Cultivation
- Hair Growth and Disorders
- Food Industry and Aquatic Biology
University of Milan
2020-2025
Abstract Local adaptation of animals to the environment can abruptly become a burden when faced with rapid climatic changes such as those foreseen for Italian peninsula over next 70 years. Our study investigates genetic structure goat populations and links it how genetics might evolve 50 We used one largest national datasets including > 1000 goats from 33 across collected by Goat Consortium genotyped k markers. results showed that be discriminated in three groups reflective geography its...
The dairy sheep industry faces ongoing challenges in optimizing cheese production and enhancing efficiency across different breeds. This study provides crucial insights into how breed-specific factors, lactation stages, parity, milk composition, including mineral concentrations, affect yield nutrients recovery the curd. aims of this were to characterize individual samples for cheesemaking by measuring 3 traits (%CY; fresh curd, TS, water retained) 5 (%REC; fat, protein, lactose, energy)...
Climate and farming systems, several of which are considered as low-input agricultural vary between goat populations from Northern Southern Italy have led to different management practices. These processes impacted genome shaping in terms inbreeding regions under selection resulted differences the northern southern populations. Both signatures can be pinpointed by analysis runs homozygosity (ROH), provides useful information assist this species rural areas.We analyzed ROH distribution (FROH)...
The inbreeding coefficient is an important parameter for livestock management. Small ruminant breeders and associations mainly rely on pedigree information, but genomic tools are gaining relevance, overcoming possible inconsistencies. This study investigates the relationship between pedigree-based in two goat four sheep dairy breeds. Pedigree data (medium-density SNPchip) were obtained 3107 goats 2511 sheep. We estimated depth (number of fully traced generations, FullGen) (FPED), as well...
This prospective cross-sectional study aimed to: (1) characterize echocardiographic features of mitral valve in MMVD affected Cavalier King Charles Spaniels (CKCS), focusing on dogs classified as American College Veterinary Internal Medicine (ACVIM) class B1; (2) compare data ACVIM B1 divided the basis age at time diagnosis, order to understand if different aged subjects had patterns. Length (AMVL), width (AMVW) and area (AMVA) anterior leaflet, prolapse, diameters annulus diastole (MVAd)...
Nowadays, several countries are developing or adopting genomic selection in the dairy goat sector. The most used method to estimate breeding values is Single-Step Genomic Best Linear Unbiased Prediction (ssGBLUP) which offers advantages terms of computational process and accuracy estimated (EBVs). Saanen Alpine predominant breeds Italy, both have similar programs where EBVs for productive traits currently calculated using BLUP. This work describes implementation these two aligning with...
Climate change and heat stress pose significant challenges to livestock. Local breeds, particularly small ruminants, are gaining importance due their adaptability harsh climates. However, the extensive system they commonly reared in leaves them exposed effects of climate change. This study aims describe distribution climate-related faced by registered Italian sheep goat breeds over past seven decades. Geolocalized data from all ruminant farms were combined with climatic information retrieved...
Cavalier King Charles spaniels (CKCSs) show the earliest onset and highest incidence of myxomatous mitral valve disease (MMVD). Previous studies have suggested a polygenic inheritance in this breed revealed an association with regions on canine chromosomes 13 14. Following clinical echocardiographic examinations, 33 not-directly-related CKCSs were selected classified as cases (n = 16) if MMVD was present before 5 years age or controls 17) no very mild after age. DNA extracted from whole...
Mannara dogs have long been bred in Sicily (Italy) to work alongside shepherds as flock guardians. This study provides a morphologic, genealogic, and genomic characterisation of the dog, useful light its recognition process improve breed standard. Morphologic measurements body, head, chest were taken on 111 adult dogs. The whole population pedigree was used calculate inbreeding coefficient (F) five effective size (Ne) parameters. Twelve genotyped using Canine 230 K SNP BeadChips compared...
Abstract Background Epidermolysis bullosa (EB) is a hereditary heterogeneous group of mechanobullous disorders caused by mutations in several structural skin proteins observed both humans and animals. In this work, we report the incidence genetic trend junctional epidermolysis (JEB), major type EB, Italian German Shorthaired Pointer (GSPs) population 10 years span. Methods study, monitored JEB GSPs from 2009 to 2018 750 The studied mutation was insertion (4818+207 ins 6.5 kb) repetitive...
This work summarizes the main results of CHEESR project, a national initiative with aim introducing innovative tools for biodiversity conservation and genetic improvements Italian small ruminant populations. Pedigrees from 81 breeds genomic data 11 case-study have been analyzed. These, together collection new phenotypes, led to development welfare- health-related first time in sheep goats. The introduction these instruments, which will continue SHEEP&GOAT contribute devise strategies...
Abstract Microsatellite markers (MS) have been widely used for parentage verification in most of the livestock species over past decades mainly due to their high polymorphic information content. In genomic era, spread genotype as single‐nucleotide polymorphism (SNP) has raised question effectively use SNPs also testing. Despite clear advantages SNP panels terms cost, accuracy, and automation, transition from MS is still very slow and, so far, only routinely applied cattle. A major difficulty...