<ns7:p>Background Curcumin, known for its anti-inflammatory properties, was selected the developing consumer friendly film forming spray that offers precise delivery of curcumin and improves patient adherence. Methods An optimized film-forming solution prepared by dissolving (1%), Eudragit RLPO (5%), propylene glycol camphor (0.5%) in ethanol: acetone (20:80) as solvent. The filled a container which contained 70% solutions 30% petroleum gas. <ns7:italic>In-vitro</ns7:italic> characterization...

The ultra-flexible lipid gel system (UFLGS) consists of bilayer membranes, responsible for highly elastic and deformable vesicles compared to conventional topical systems. Varicose veins are abnormal, dilated blood vessels resulting from weakening in the wall vessels. A flavonoid diosmin is potential alleviate circulatory issues by altering veins’ elasticity suppleness. Schrodinger 2023-1 suite device was used molecular docking study. Ultra-flexible nanosuspension (UFLNS) developed...

Objective: Piroxicam is a long-acting potent nonsteroidal anti-inflammatory drug (NSAID) which has very low solubility in Gastrointesti nal (GI) fluids results poor bioavailability after oral administration.The present investigation aimed to formulate and evaluate fast dissolving films containing piroxicam overcome problems thereby facilitate the convenience of pediatric geriatric patients.Method: The inclusion complexes with β-cyclodextrin were prepared.In vitro dissolution study was...

Objective: The present study was aimed at formulating and evaluating a novel solid self‑nano emulsifying drug delivery system (SNEDDS) to increase the solubility bioavailability of hydrochlorothiazide (HCZ). Enhancing both drugs remain cornerstone for achieving successful outcomes systems. Furthermore, employing nanotechnology‑based formulations such as SNEDDS offers important advantage; most is protection from enzymatic or chemical degradation. Materials Methods: Liquid (L‑SNEDDS) prepared...

Self-emulsifying drug delivery systems (SEDDSs) represent a significant breakthrough in addressing bioavailability challenges by enhancing the solubilization of poorly water-soluble drugs, ensuring consistent formulation properties, and facilitating easy industrial scale-up. Despite their liquid form posing some limitations, these can be effectively addressed solidifying SEDDSs, offering numerous advantages. The solidification SEDDS has opened avenues for overcoming limitations associated...

Cell membrane-coated Nano-Liposomes (CM-NLPs) offer a promising approach that combines the advantages of both host cells and synthetic nano-liposomes (NLPs). This technique involves coating liposomes with red blood cell (RBC) membranes to enhance their functionality. In this study, novel carboplatin-loaded NLPs (CP-NLPs) were formulated using phospholipids (Soya Phosphatidyl Choline) cholesterol through thin-film hydration method, optimized 3

Alzheimer's disease is the most common type of dementia. Oxidative stress involved in progression aging and disease. It known that lutein a carotenoid having antioxidant properties. The present research explores Lutein loaded chitosan nanoparticles for Suppressing Stress treatment Alzheimer's. developed are administered through nose to target brain via nose-to-brain pathway. For optimization formulation systematic QbD approach was used. further characterized Physicochemical parameters,...

Background: Asiatic acid (AA) is a naturally occurring triterpenoid derivative of Centella asiatica (CA) with neuroprotective effect. The study aimed to design an ideal oral drug delivery system treat Alzheimer's disease (AD) and develop chitosan-embedded liposomes comprising extract CA (CLCAE) compare them the chitosan-coated asiatic (CLAA) for initial phases AD. Methods: solvent evaporation technique was used CLCAE CLAA, optimised experiment's design, further evaluated. Results: Nuclear...

Objective: The aim of the present study was to prepare hydrogel matrix tablets for controlled release an anti-asthma drug (Montelukast sodium) by modifying applications chitosan crosslinking it with different cross linking agent.Methods: hydrogels were prepared using three agents namely, anhydrous dextrose (DXT), sodium tripolyphosphate (TPP) and glutaraldehyde (GL). Formulations direct compression method pre post parameters evaluated.Results: FTIR (Fourier transform infrared spectroscopy)...

Objective: Asiatic acid is a triterpene saponin and the main constituent of species Centellaasiatica. The current study aimed to isolate, characterize develop an analytical method for asiatic in shorter run time with good efficiency.&#x0D; Methods: In this isolation was achieved by TLC thus isolated characterized 1HNMR spectral analysis LCMS. An isocratic RP-HPLC established assessment from methanol extract chromatographic separations were RP-C18 column 250x4.6 mm (5µ Particle size) Shimadzu...

<ns4:p><ns4:bold>Introduction</ns4:bold>: Posaconazole is a widely used antifungal drug, and its accurate quantification essential for quality control assessment of pharmaceutical products. This study aimed to develop validate reverse-phase high-performance liquid chromatography (HPLC) analytical method quantifying in bulk dosage form.</ns4:p><ns4:p> </ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold>: The HPLC was developed validated based on International Conference Harmonisation (ICH)...

In Vitro Antimicrobial and Antioxidant Activity of Chitosan Isolated from Podophthalmus VigilK. Prabu E. Natarajan

Nuclear medicine, a vital component of modern healthcare, harnesses the power radioactive isotopes to enable precise diagnoses and treatments. However, handling materials poses inherent risks. This study introduces an automated drug dispensing system (ADDS) within nuclear medicine department enhance safety efficiency. The research comprehensively evaluates ADDS implementation’s financial operational feasibility, considering staff perceptions acceptance. Findings reveal that RESCUEDOSE,...

Solutions of drugs may behave as ideal solutions, real or irregular solutions. It is necessary to understand the behaviour these solutions before attempting handle them. Various theories/models are reported in literature explain their behaviour. The importance models predicting solubility aripiprazole demonstrated using its dioxane-water blends. method utilizes theoretical and semiempirical approaches predict solubility. experimental data for validated both nonideal focusing on...

The objective of this study was to design and investigate the antifungal activity proniosomal gel eugenol for treatment oral candidiasis. prepared by coacervation phase separation method using different surfactants like spans 20, 60, 80, soya lecithin cholesterol. formulations were evaluated visual inspection, pH detection, viscosity, spreadability, in vitro drug release kinetics study, vivo studies. compatibility indicated that excipients compatible with each other. results showed pH,...

Abstract: Objective: The aim of this observational research study was to bring up the issues related Communication skill (CS) and Good documentation practice (GDP) in one pharmacy college India its impact on students their overall personality development job perspectives. These skills are like an accelerator which is required facilitate smooth sailing business. Methods: new model developed employed conduct for final year B. Pharm M. called as Classroom Record-Daily laboratory Record-Human...

Objectives: The main objective of the present investigation was to develop and compared conventional, chitosan-coated electrosteric stealth liposomes Rivastigmine Tartrate for treatment Alzheimer's Disease. Methods: solvent evaporation method employed prepare optimized by Design Experiment approach. effect various process parameters investigated on particle size percentage entrapment efficiency. compatibility studies were carried out using Fourier Transform Infrared Spectroscopy....