Alam Khan

ORCID: 0000-0002-2482-7403
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Essential Oils and Antimicrobial Activity
  • Medicinal Plants and Neuroprotection
  • Natural product bioactivities and synthesis
  • Phytochemistry and Biological Activities
  • Phytochemicals and Antioxidant Activities
  • Phytochemical compounds biological activities
  • Maternal and Perinatal Health Interventions
  • Piperaceae Chemical and Biological Studies
  • Developmental Biology and Gene Regulation
  • Insect Pest Control Strategies
  • Pluripotent Stem Cells Research
  • Pharmacological Effects of Natural Compounds
  • Natural Antidiabetic Agents Studies
  • Autophagy in Disease and Therapy
  • Congenital heart defects research
  • Animal Diversity and Health Studies
  • Bone Tissue Engineering Materials
  • Maternal and fetal healthcare
  • Traditional and Medicinal Uses of Annonaceae
  • Ethnobotanical and Medicinal Plants Studies
  • Global Maternal and Child Health
  • Probiotics and Fermented Foods
  • Environmental Toxicology and Ecotoxicology
  • Psidium guajava Extracts and Applications
  • Microbial Natural Products and Biosynthesis

University of Rajshahi
2015-2025

The University of Texas Southwestern Medical Center
2025

Northwest General Hospital and Research Center
2024

University of Agriculture Faisalabad
2021-2022

Scripps Research Institute
2015-2021

Saitama University
2010-2018

University of Dhaka
2013

Kasetsart University
2010

The University of Agriculture, Peshawar
2004

North Carolina State University
1976-1977

Abstract Background Antioxidant compounds like phenols and flavonoids scavenge free radicals thus inhibit the oxidative mechanisms that lead to control degenerative other diseases. The aim of this study was investigate antioxidant activity in vitro , total phenolic flavonoid contents ethanol extracts fractions Crescentia cujete leaves stem bark. Methods bark crude extract (CEE) their partitionates petroleum ether (PEF), chloroform (CHF), ethyl acetate (EAF) aqueous (AQF) were firstly...

10.1186/1472-6882-14-45 article EN cc-by BMC Complementary and Alternative Medicine 2014-02-04

Background and Purpose Despite the well‐known occurrence of hypothermia during sepsis, its underlying biological nature adaptive value remain debated. Experimental Approach Using indirect calorimetry, telemetry, thermal gradient studies pharmacological studies, we examined metabolic responses mice treated with a shock‐inducing lethal dose lipopolysaccharide (LPS). Key Results We report that LPS‐treated undergo spontaneous hypothermia, driven by hypometabolism cold‐seeking behaviours, even...

10.1111/bph.70000 article EN cc-by-nc-nd British Journal of Pharmacology 2025-02-23

Spns1 (Spinster homolog 1 [Drosophila]) in vertebrates, as well Spin (Spinster) Drosophila, is a hypothetical lysosomal H+-carbohydrate transporter, which functions at late stage of macroautophagy (hereafter autophagy). The Spin/Spns1 defect induces aberrant autolysosome formation that leads to developmental senescence the embryonic and premature aging symptoms adulthood. However, molecular mechanism by loss specific pathogenesis remains be elucidated. Using chemical, genetic...

10.1080/15548627.2016.1256934 article EN Autophagy 2016-11-22

To assess the in vitro antibacterial, antifungal and cytotoxic activities of amblyone, a triterpenoid isolated from Amorphophallus campanulatus (Roxb).Disc diffusion technique was used for antibacterial screening. Cytotoxicity determined against brine shrimp nauplii. In addition, minimum inhibitory concentration (MIC) using serial dilution to determine potency.Large zones inhibition were observed disc screening four Gram-positive bacteria (Bacillus subtilis, Bacillus megaterium,...

10.4103/0253-7613.40489 article EN Indian Journal of Pharmacology 2008-01-01

Abstract Background Medically unnecessary caesarean section (CS) is now an ongoing concern worldwide including in Bangladesh. This intensifies the occurrence of adverse maternal and child health outcomes. We investigated associations CS with some basic behavioural outcomes mothers their children Methods conducted a community-based case–control study from May to August 2019. A total 600 mother–child dyads were interviewed using structured questionnaire, 300 them had CS, vaginal delivery (VD)...

10.1186/s41043-022-00326-6 article EN cc-by Journal of Health Population and Nutrition 2022-10-04

Objectives: The objective of this study was to assess the effects varying glucose and trehalose concentrations on tris-citric acid-egg yolk-fructose (TCEF) diluents for short-term cold storage goat semen. Materials Methods: semen sample collected, unwashed, divided into following groups: control (TCEF without trehalose), TCEF + (75, 150 mm), mm). Each experimental sperm group (sperm concentration: 9×10<sup>7</sup>/ ml) kept at 4°C in a refrigerator. impact levels quality...

10.5455/javar.2025.l895 article EN cc-by Journal of Advanced Veterinary and Animal Research 2025-01-01

Background: Fetal malposition play a vital role in the progress of labor and correct identification fetal position may impact mode delivery. The main purpose this comparative cross-sectional study is to diagnose on vaginal versus ultrasound examination before attempting instrumental delivery at tertiary care hospital setting Pakistan. Place Duration: Gynaecology Obstetrics department Tertiary hospital, August 2023 - January 2024. Methods: Pregnant females with singleton pregnancy any age...

10.55519/jamc-01-13954 article EN Journal of Ayub Medical College Abbottabad 2025-03-15

The effect of cinnamon doses on blood serum glucose was studied in type 2 diabetic individuals for 60 days.Sixty both sexes and age 48±6.5 years were divided into 6 groups; each group having 10 individuals.Groups 1, 3 assigned 1g, 3g 6g doses/day respectively.Groups 4, 5 placebo respectively.The equally distributed over the day.Cinnamon given form capsules with breakfast, lunch dinner.The 40 days after days; there a 20 blank period.Fasting samples taken 0 (starting day experiment) 20, serums...

10.3923/pjn.2004.268.272 article EN Pakistan Journal of Nutrition 2004-08-15

Abstract Carbofuran is a broad‐spectrum synthetic pesticide. Its exposure to non‐target mammals affects the biological system through induction of oxidative stress. Since stress major contributing factor cellular autophagy and senescence, our present investigation determined impacts carbofuran‐induced on senescence. A transmembrane protein, Spinster homolog 1 (Spns1), involved in autophagic lysosomal metabolism. mutation accelerates senescence shortens lifespan. Using transgenic zebrafish...

10.1111/jcmm.16774 article EN cc-by Journal of Cellular and Molecular Medicine 2021-07-09

Abstract Objective To evaluate the antimicrobial and cytotoxic activity of acetone extract leaves Abroma augusta. Methods Disc diffusion method was used to demonstrate antibacterial antifungal activities. Cytotoxicity determined against brine shrimp nauplii. In addition, minimum inhibitory concentration (MIC) using serial dilution technique determine potency. Results The showed significant activities three gram-positive (Bacillus subtilis, Bacillus megaterium Staphylococcus aureus) four...

10.1016/s2221-1691(12)60429-8 article EN Asian Pacific Journal of Tropical Biomedicine 2012-01-01

A sponge template method was used to synthesize scaffolds from hydroxyapatite (HAp) using varying sintering temperatures and compressive ratios. The HAp were fabricated with collagen (COL) or collagen/HAp particles under room temperature coating conditions. microstructure mechanical properties of the biomaterials analyzed by FE-SEM EZ Test, respectively. micrographs showed microporous structure composite scaffolds. Incorporation COL COL/HAp into pure conditions significantly reduced porosity...

10.1080/21870764.2019.1600226 article EN cc-by-nc Journal of Asian Ceramic Societies 2019-03-27

Abstract Carbofuran is a carbamate pesticide, widely used in agricultural practices to increase crop productivity. In mammals, carbofuran known cause several untoward effects, such as apoptosis the hippocampal neuron, oxidative stress, loss of memory and chromosomal anomalies. Most these effects are implicated with cellular senescence. Therefore, present study aimed determine effect on senescence biological ageing. Spinster homolog 1 (Spns1) transmembrane transporter, regulates autolysosomal...

10.1111/jcmm.16171 article EN cc-by Journal of Cellular and Molecular Medicine 2020-12-04
Coming Soon ...