A5063492835- interferon and immune responses
- Pharmacogenetics and Drug Metabolism
- Hormonal Regulation and Hypertension
- Cardiac electrophysiology and arrhythmias
- Pluripotent Stem Cells Research
- Congenital heart defects research
- Drug Transport and Resistance Mechanisms
- Pulmonary Hypertension Research and Treatments
- Estrogen and related hormone effects
- Semantic Web and Ontologies
- Laser-Matter Interactions and Applications
- Developmental Biology and Gene Regulation
- Hepatitis B Virus Studies
- Eicosanoids and Hypertension Pharmacology
- Lipoproteins and Cardiovascular Health
- Renin-Angiotensin System Studies
- Plant Molecular Biology Research
- Renal and related cancers
- Electrostatic Discharge in Electronics
- Cell death mechanisms and regulation
- Cell Adhesion Molecules Research
- Laser Design and Applications
- Microbial Inactivation Methods
- Cardiac Valve Diseases and Treatments
- Genomics and Chromatin Dynamics
Icahn School of Medicine at Mount Sinai
2022-2024
Jawaharlal Institute of Post Graduate Medical Education and Research
2009-2016
CYP2C19 is a polymorphic enzyme involved in the metabolism of clinically important drugs. Genotype-phenotype association studies have reported wide ranges metabolic ratios its substrates. These discrepancies could be attributed to variations promoter region and this aspect has been recently. The observations recent reports on influence variants substrates might also influenced by copy number . In paper, we describe using real-time polymerase chain reaction comparative Ct method. No were...
Background: Heart failure (HF) is a complex clinical condition associated with substantial morbidity and mortality worldwide. The contractile dysfunction arrhythmogenesis related to HF has been linked the remodelling of calcium (Ca ++ ) handling. Phospholamban (PLN) emerged as key regulator intracellular Ca concentration. Of PLN mutations, L39X intriguing it not fully characterized. This mutation believed be functionally equivalent null (KO) but contrary KO mice, carriers develop lethal...