A5040944480- Obesity, Physical Activity, Diet
- Children's Physical and Motor Development
- Cardiovascular and exercise physiology
- Dementia and Cognitive Impairment Research
- Diet and metabolism studies
- Physical Activity and Health
- Cardiac Health and Mental Health
- Gut microbiota and health
- Health and Lifestyle Studies
- Advanced Neuroimaging Techniques and Applications
- Adipose Tissue and Metabolism
- Heart Rate Variability and Autonomic Control
- Alzheimer's disease research and treatments
- Attention Deficit Hyperactivity Disorder
- Effects of Vibration on Health
- Infant Development and Preterm Care
- Health disparities and outcomes
- Adipokines, Inflammation, and Metabolic Diseases
- Neonatal and fetal brain pathology
- Sports injuries and prevention
- Eating Disorders and Behaviors
- Nutrition and Health in Aging
- Cardiovascular Disease and Adiposity
- EEG and Brain-Computer Interfaces
- Birth, Development, and Health
Universidad de Granada
2019-2025
Universidad Andrés Bello
2020-2025
Translational Research Institute for Metabolism and Diabetes
2024-2025
Hospital Universitario Virgen de las Nieves
2022-2024
Viña del Mar University
2024
University of Pittsburgh
2024
Children's Hospital of Pittsburgh
2024
Instituto de Investigación Biosanitaria de Granada
2023
Erasmus MC
2022
Departamento de Educación
2022
New microbiome sequencing technologies provide novel information about the potential interactions among intestinal microorganisms and host in some neuropathologies as autism spectrum disorders (ASD). The microbiota–gut–brain axis is an emerging aspect generation of autistic behaviors; evidence from animal models suggests that microbial shifts may produce changes fitting clinical picture autism. aim present study was to evaluate fecal metagenomic profiles children with ASD compare them...
Pediatric overweight and obesity are highly prevalent across the world, with implications for poorer cognitive brain health. Exercise might potentially attenuate these adverse consequences.To investigate effects of an exercise program on health indicators, including intelligence, executive function, academic performance, outcomes, among children or to explore potential mediators moderators main exercise.All preexercise postexercise data this 20-week randomized clinical trial 109 aged 8 11...
Abstract Whereas numerous studies have investigated the relationship of cardiorespiratory fitness with inhibition and neuroelectric activity, role other physical components activity (PA) intensities in this remain unclear, especially children obesity. Therefore, purpose study was to investigate association fitness, PA, sedentary time inhibitory control children. Eighty‐four (8‐11 years) overweight or obesity performed ALPHA battery assess their (i.e., muscular strength, speed‐agility,...
Individuals with coronary artery disease have poorer mental health, health-related quality of life (HR-QoL), and cognition compared (age-matched) controls. Exercise training may attenuate these effects. The aim is to systematically review meta-analyse the effects different exercise types settings on brain structure/function, cognition, HR-QoL, health (e.g. depression, anxiety), sleep in patients disease. A systematic search was conducted a network meta-analysis (i) types, high-intensity...
We investigated the associations of different sedentary behaviors (SB) with gray matter volume and we tested whether SB related to is associated intelligence. Methods: 99 children overweight or obesity aged 8–11 years participated in this cross-sectional study. was measured using Youth Activity Profile-Spain questionnaire. T1-weighted images were acquired a 3.0 T Magnetom Tim Trio system. Intelligence assessed Kaufman Brief Test. Whole-brain voxel-wise multiple regression models used test...
Abstract Objective To investigate whether a 20‐week aerobic and resistance exercise program induces changes in brain current density underlying working memory inhibitory control children with overweight/obesity. Methods A total of 67 (10.00 ± 1.10 years) were randomized into an or group. Electroencephalography (EEG)‐based (μA/mm 2 ) was estimated using standardized low‐resolution electromagnetic tomography (sLORETA) during task (Delayed non‐matched‐to‐sample task, DNMS) (Modified flanker...
Education and health are crucial topics for public policies as both largely determine the future wellbeing of society. Currently, several studies recognize that physical activity (PA) benefits brain in children. However, most these have not been carried out developing countries or lack transference into education field. The Cogni-Action Project is divided two stages, a cross-sectional study crossover-randomized trial. aim first part to establish associations PA, sedentarism, fitness with...
This study aimed to establish the association and differences in a diversity of cognitive domains according cardiorespiratory fitness (CRF), muscular (MF), speed‐agility (S‐AF) level large sample Chilean schoolchildren. 1171 schoolchildren aged 10–14 years participated. CRF, MF, S‐AF were assessed through ALPHA‐fitness test battery. Cognition was evaluated NeuroCognitive Performance Test, which involved eight tests related four main domains: flexibility (CF), working memory (WM), inhibitory...
Emerging research supports the idea that exercise positively affects neurodevelopment. However, mechanisms linking with brain health are largely unknown. We aimed to investigate effect of on (a) blood biomarkers selected based previous evidence (brain-derived neurotrophic factor, β-hydroxybutyrate (BHB), cathepsin B (CTSB), kynurenine, fibroblast growth factor 21 (FGF21), soluble vascular cell adhesion molecule-1 (sVCAM-1)); and (b) a panel 92 neurology-related proteins (discovery analysis)....
The aim was to investigate the associations between different physical activity (PA) patterns and sedentary time (ST) with vitamin D deficiency (<12 ng/mL) in a large sample of Chilean women. In this cross-sectional study, final included 1245 adult 686 older PA levels, mode commuting, ST, leisure-time were self-reported. Vitamin defined as <12 ng/mL insufficiency <20 ng/mL. A higher ST associated (odds ratio (OR): 2.4, 95%: 1.6–4.3) adults, passive commuting (OR: 1.7, 1.1–2.7)....
Aim: To determine differences in physical activity (PA) levels and energy expenditure a group of university students according to their length stay the university.
To examine the associations between muscular strength and mental health. We used baseline data of 91 cognitively healthy older adults (71.69 ± 3.91 years old, 57 % women) participating in AGUEDA randomized controlled trial. Muscular was assessed using both objective (i.e., handgrip strength, biceps curl, squats, isokinetic test) perceived International Fitness Scale) indicators. Psychological ill-being indicators: anxiety, depression, stress, loneliness; psychological well-being satisfaction...
<title>Abstract</title> High-performance, resource-efficient methods for plasma amyloid-β (Aβ) quantification in Alzheimer’s disease are lacking; existing mass spectrometry-based assays resource- and time-intensive. We developed a streamlined spectrometry method with single immunoprecipitation step, an optimized buffer system, ≤75% less antibody requirement. Analytical clinical performances were compared in-house reproduced version of well-known two-step assay. The assay showed high dilution...
Summary Background Children with overweight/obesity have poorer sleep and smaller gray matter volume (GMV) than normal‐weight children. No studies investigated the associations of objectively‐assessed GMV in children overweight/obesity, or their implications for academic cognitive outcomes. Objectives To explore behaviors whole brain particularly hippocampus as a region interest independent sedentary time (SED) physical activity; to assess whether associated regions was related achievement,...
Alzheimer’s disease is currently the leading cause of dementia and one most expensive, lethal severe diseases worldwide. Age-related decline in executive function widespread plays a key role subsequent risk. Physical exercise has been proposed as non-pharmaceutical approaches to improve ameliorate cognitive decline. This single-site, two-arm, single-blinded, randomized controlled trial (RCT) will include 90 cognitively normal older adults, aged 65–80 years old. Participants be 24-week...
Cardiac autonomic function can be quantified through mean heart rate (HR) or variability (HRV). Numerous studies have supported the utility of different HRV parameters as indicators cardiorespiratory fitness (CRF). However, HR has recently shown to a stronger predictor CRF than in healthy young adults, yet these findings need replicated, other age groups such children. Therefore, this study aimed: (1) associations between cardiac (HR, standard and corrected parameters) overweight/obese...
Background : Physical fitness and fatness converge simultaneously modulating cognitive skills, which in turn, are associated with children adolescents’ socioeconomic background. However, both components fat mass localization crucial for understanding its implication at the level. Objective This study aimed to determine mediation role of a global physical score on association between different indicators related distribution performance, explore influence school vulnerability. Methods In this...
The first aim was to compare differences between school vulnerability groups, fitness levels, and their combination in adolescent cognitive performance. second determine the mediation role of association A total 912 Chilean adolescents aged 10–14 years participated this study. index (SVI) assigned by Government categorized into high-, mid-, or low-SVI. Adolescents were classified as fit unfit according global z-score computed from cardiorespiratory (CRF), muscular (MF), speed/agility (SAF)...