A5050623226- Advanced Chemical Sensor Technologies
- Metabolomics and Mass Spectrometry Studies
- Liver Disease Diagnosis and Treatment
- Numerical methods in engineering
- Pancreatic and Hepatic Oncology Research
- Pancreatic function and diabetes
- Composite Material Mechanics
- Electromagnetic Simulation and Numerical Methods
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Cardiovascular and exercise physiology
- Polyamine Metabolism and Applications
- Mass Spectrometry Techniques and Applications
University of Eastern Finland
2018-2022
Finland University
2022
Kanta-Hämeen Keskussairaala
2021
Kuopio University Hospital
2018
University of Oulu
2003
Background/Aim: Most pancreatic cancer patients are diagnosed at an advanced stage, since the diagnosis is demanding. Field asymmetric waveform ion mobility spectrometry (FAIMS) a sensitive technique used for detection of volatile organic compounds (VOC). We evaluated ability FAIMS to discriminate between and healthy controls from urine sample. Patients Methods: For proof-of-concept study in three Finnish hospitals, 68 with cancer, 36 acute pancreatitis, 18 chronic 8 pre-malign lesions 52...
Polyamines play an important role in cellular proliferation, and the change polyamine metabolism is reported various cancers. We searched for urinary signature distinguishing between pancreatic cancer, premalignant lesions of pancreas (PLP), acute chronic pancreatitis, controls.Patients controls were prospectively recruited three Finnish hospitals October 2013 June 2016. The patients provided a urine sample at time diagnosis. panel 14 polyamines was obtained single run with mass...
Detection of volatile organic compounds (VOCs) from bodily fluids with field asymmetric waveform ion mobility spectrometry (FAIMS) and related methods has been studied in various settings. Preliminary results suggest that it is possible to detect prostate, colorectal, ovarian pancreatic cancer urine samples. In this study, our primary aim was differentiate pancreatitis benign tumours the pancreas by using bile samples obtained during endoscopic retrograde cholangiopancreatography (ERCP)....