A5027428414- Skin and Cellular Biology Research
- Cellular Mechanics and Interactions
- Redox biology and oxidative stress
- Silk-based biomaterials and applications
- Cancer Cells and Metastasis
- Human Resource Development and Performance Evaluation
- Microtubule and mitosis dynamics
- Nanoplatforms for cancer theranostics
- Biocrusts and Microbial Ecology
- Nanoparticle-Based Drug Delivery
- Hair Growth and Disorders
- Plant Reproductive Biology
- Simulation-Based Education in Healthcare
- Innovations in Medical Education
- Healthcare Regulation
- Cardiovascular Health and Disease Prevention
- Wnt/β-catenin signaling in development and cancer
- Fish biology, ecology, and behavior
- Aquaculture Nutrition and Growth
- Electron Spin Resonance Studies
- Nitric Oxide and Endothelin Effects
- Advanced Fluorescence Microscopy Techniques
- Dyeing and Modifying Textile Fibers
- Science and Education Research
- Glioma Diagnosis and Treatment
Institute for Systems Engineering and Computers
2025
INESC TEC
2025
University of Coimbra
2020-2022
CUF Porto Hospital
2022
Universidade do Porto
2022
Keratin intermediate filaments are the principal structural element of epithelial cells. Their importance in providing bulk cellular stiffness is well recognized, but their role mechanics cell cortex less understood. In this study, we therefore compared cortical three keratinocyte lines: primary wild type cells (NHEK2), immortalized (NEB1) and mutant (KEB7). The was measured by lateral indentation with AOD-steered optical tweezers without employing any moving mechanical elements. method...
Abstract Keratin intermediate filaments are the principal structural element of epithelial cells. Their importance in providing bulk cellular stiffness is well recognized, but their role mechanics cell cortex less understood. In this study, we therefore compared cortical three keratinocyte lines: primary wild type cells (NHEK2), immortalized (NEB1) and mutant (KEB7). The was measured by lateral indentation with AOD-steered optical tweezers without employing any moving mechanical elements....
Keratins are one of the most abundant proteins in epithelial cells. They form a cytoskeletal filament network whose structural organization seriously conditions its function. Dynamic keratin particles and aggregates often observed at periphery mutant keratinocytes related to hereditary skin disorder epidermolysis bullosa simplex, which is due mutations keratins 5 14. To account for their emergence cells, we extended an existing mathematical model turnover wild-type cells developed novel 2D...
Introduction: There is a paucity of quantitative studies objectively comparing debriefing and feedback as methods for post-scenario discussion its impact on healthcare teams’ acquisition retention non-technical skills. The main purpose this study to provide some insight research question, using sample medical students. A secondary objective explores students’ opinion preference the discussion.Material Methods: Forty-five students were distributed among 15 teams, randomly allocated two...
We examined keratin aggregate formation and the possible mechanisms involved. With this aim, we observed effect that different ratios between mutant wild-type keratins expressed in cultured keratinocytes may have on vitro , as well how affects mechanical properties of cells at cell cortex. To end prepared clones with expression rates close to 25%, 50% 100% EGFP-K14 proteins (either WT or R125P V270M mutants). Our results showed only case 25% significant differences could be seen. Namely,...
This study aims to investigate the relationship between Science, Technology and Society Perspective, Curriculum Integrated Secondary Education based on academic productions available digital research platforms.The theoretical framework was built from authors Lopes Macedo, Auler, Araújo Frigotto, Ramos Saviani.This is an integrative literature review with a qualitative approach.The search for works conducted Brazilian Digital Library of Theses Dissertations Google Scholar platforms through...