INTRODUCTION Renewed interest in whole blood (WB) resuscitation civilians has emerged following its military use. There is a paucity of data on role where balanced component therapy (CT) the standard care. The aim this study was to assess nationwide outcomes using WB as an adjunct CT versus alone resuscitating civilian trauma patients. METHODS We analyzed (2015–2016) Trauma Quality Improvement Program. included adult (age, ≥18 years) patients presenting with hemorrhagic shock and requiring...

Whole blood (WB) has shown promise in pediatric trauma resuscitation following its prominent role the of adult patients. Although WB children been to be feasible, effectiveness yet explored. The aim this study was examine outcomes transfusion as an adjunct component therapy (CT) compared with CT only early for patients.Children aged 1 17 years, who were transfused within 4 hours presentation, identified Trauma Quality Improvement Program 2017 database. Patients stratified into those...

Abstract Patients admitted to the intensive care unit frequently have anemia and impaired renal function, but often lack historical blood results contextualize acuteness of these findings. Using data available within two hours ICU admission, we developed machine learning models that accurately (AUC 0.86–0.89) classify an individual patient’s baseline hemoglobin creatinine levels. Compared assuming be same as admission lab value, performed significantly better at classifying acute kidney...

BACKGROUND Blunt cerebrovascular injury (BCVI) is associated with accidents (CVA). Early therapy antiplatelet agents or anticoagulants recommended. There are limited data comparing the effectiveness of these treatments. The aim our study was to compare outcomes between BCVI patients who received versus those agents. METHODS We performed an (2011–2015) analysis Nationwide Readmission Database and included all adult trauma 18 years older had isolated (other body regions Abbreviated Injury...

BACKGROUND Tetrahydrocannabinoids (THC) can modulate the coagulation cascade resulting in hypercoagulability. However, clinical relevance of these findings has not been investigated. The aim our study was to evaluate impact preinjury marijuana exposure on thromboembolic complications (TEC) trauma patients. METHODS We performed a 2-year (2015–2016) analysis American College Surgeons Trauma Quality and Improvement Program database included all adult (≥18 year) Patients were stratified based...

Trauma-induced coagulopathy is frequently associated with hypofibrinogenemia. Cryoprecipitate (Cryo), and fibrinogen concentrate (FC) are both potential means of supplementation. The aim this study was to compare the outcomes traumatic hemorrhagic patients who received supplementation using FC versus Cryo.We performed a 2-year (2016-2017) retrospective cohort analysis American College Surgeons Trauma Quality Improvement Program database. All adult trauma (≥18 years) or Cryo as an adjunct...

INTRODUCTION Organ dysfunction following traumatic brain injury (TBI) is common and has been associated with unpredictable outcomes. The aim of our study to describe the incidence non-neurological organ (NNOD) its impact on outcomes in patients severe TBI admitted intensive care unit (ICU). METHODS We performed a 3-year (2015-2017) review Level 1 trauma center’s prospectively maintained database included all adult (age ≥18y) isolated (head abbreviated severity (AIS) ≥3 other AIS <3) an...

The volume-outcome relationship led to the regionalization of trauma care. between centers' injury-specific laparotomy volume and outcomes has not been explored. aim our study was examine a center's in blunt penetrating patients.We performed (2017) analysis Trauma Quality Improvement Program database. We included adult (age, ≥18 years) patients who required emergent laparotomies for hemorrhage control. centers were stratified based on their volumes: high (HV), ≥25 cases per year; medium...

Studies have proposed the use of antibiotics only in cases acute uncomplicated appendicitis (AUA). However, there remains a paucity data evaluating this nonoperative approach vulnerable frail geriatric population. The aim study was to examine long-term outcomes patients with AUA treated appendectomy compared initial management (NOP).We conducted 1-year (2017) analysis Nationwide Readmissions Database and included all patients(age, ≥65 years) diagnosis AUA. Frailty assessed using five-factor...

Never-frozen liquid plasma (LQP) was found to reduce component waste, decrease health care expenses, and have a superior hemostatic profile compared with fresh frozen (FFP). Although transfusing LQP in hemorrhaging patients has become more common, its clinical effectiveness remains be explored. This study aims examine outcomes of trauma transfused thawed FFP.Adult (≥18 years) receiving early (≤4 hours) transfusions were identified the Trauma Quality Improvement Program 2017. Patients...

INTRODUCTION Quetiapine is an atypical antipsychotic commonly used in critical care. Cellular and animal models demonstrated its novel anti-inflammatory properties traumatic brain injury (TBI). Our study aimed to assess the effect of quetiapine on outcomes critically ill TBI patients. We hypothesize that improves neurological outcomes. METHODS The Multiparameter Intelligent Monitoring Intensive Care database was queried, all adult (age, ≥18 years) isolated patients (extracranial Abbreviated...

The use of whole blood (WB) for the treatment hemorrhagic shock and coagulopathy is increasing in civilian trauma patients. Four-factor prothrombin complex concentrate (4-PCC) adjunct to component therapy showed improved outcomes Our study aims evaluate patients who received 4-PCC WB (4-PCC-WB) compared with alone.We performed a 3-year (2015-2017) analysis American College Surgeons-Trauma Quality Improvement Program database. All adult (age, ≥18 years) were included. We excluded on preinjury...

Several advancements in hemorrhage control have been advocated for the past decade, including balanced transfusions and earlier times to intervention. The aim of this study was examine effect these on outcomes blunt trauma patients undergoing emergency laparotomy.This is a 5-year (2013-2017) analysis Trauma Quality Improvement Program. Adult (18 years or older) with early (≤4 hours) packed red blood cell (PRBC) fresh frozen plasma (FFP) an laparotomy were identified. Time-trend 24-hour...

The aim of the study was to quantify nutritional losses related pre- and postoperative fasts in critically ill intubated patients explore whether shorter are safe appropriate this population. A retrospective review mechanically ventilated adults undergoing surgery more than 24 hours after admission a Level I trauma center over 15 months done, which yielded 132 procedures 81 unique patients. Ninety per cent preoperative periods 43 were affected by nonmedical barriers feeding. Eighty-two...