A5027581116- Insect and Pesticide Research
- Plant and animal studies
- Insect and Arachnid Ecology and Behavior
- Nuclear Structure and Function
- RNA Research and Splicing
- Healthcare and Venom Research
- Genomics and Chromatin Dynamics
- Parkinson's Disease Mechanisms and Treatments
- CRISPR and Genetic Engineering
- DNA Repair Mechanisms
- Bee Products Chemical Analysis
- Food Allergy and Anaphylaxis Research
- Genetics, Aging, and Longevity in Model Organisms
- Insect-Plant Interactions and Control
- Insect Pest Control Strategies
- Pesticide Exposure and Toxicity
- Insect symbiosis and bacterial influences
Landesbetrieb Landwirtschaft Hessen
2016-2024
Fraunhofer Institute for Molecular Biology and Applied Ecology
2013-2019
Institute of Molecular Biology
2013-2019
Heidelberg University
2006-2008
The assessment of pesticide risks to insect pollinators have typically focused on short-term, lethal impacts. environmental ramifications many the world's most commonly employed pesticides, such as those exhibiting systemic properties that can result in long-lasting exposure insects, may thus be severely underestimated. Here, seven laboratories from Europe and North America performed a standardised experiment (a ring-test) study long-term sublethal impacts relatively recently approved 'bee...
The effect of pesticides on insects is often discussed in terms acute and chronic toxicity, but an important overlooked aspect the impact sublethal doses insect physiology behavior. Pesticides can influence various physiological parameters insects, including innate immune system, development, reproduction, through a combination direct effects specific exposed tissues modification behaviors that contribute to health reproductive success. Such include mobility, feeding, oviposition,...
Abstract Queen health is crucial to colony survival of honeybees, since reproduction and growth rely solely on the queen. failure considered a relevant cause losses, yet few data exist concerning effects environmental stressors queens. Here we demonstrate for first time that exposure field-realistic concentrations neonicotinoid pesticides can severely affect immunocompetence queens western honeybees ( Apis mellifera L.). In young exposed thiacloprid (200 µg/l or 2000 µg/l) clothianidin (10...
Abstract Sublethal doses of pesticides affect individual honeybees, but colony-level effects are less well understood and it is unclear how the two levels integrate. We studied effect neonicotinoid pesticide clothianidin at field realistic concentrations on small colonies. found that exposure to affected worker jelly production workers created a strong dose-dependent increase in mortality larvae, strikingly population size capped brood remained stable. Thus, hives exhibited short-term...
The nuclear lamina consists of a meshwork lamins and lamina-associated proteins, which provide mechanical support, control size shape the nucleus, mediate attachment chromatin to envelope. Abnormal shapes are observed in aging cells humans nematode worms. expression laminDelta50, constitutively active lamin A splicing variant Hutchinson-Gilford progeria syndrome patients, leads lobulation envelope accompanied by DNA damage, loss heterochromatin. So far, it has been unclear whether these...
Abstract Solitary bees are frequently exposed to pesticides, which considered as one of the main stress factors that may lead population declines. A strong immune defence is vital for fitness bees. However, system can be weakened by environmental render more vulnerable parasites and pathogens. Here we demonstrate first time field-realistic concentrations commonly used neonicotinoid insecticide thiacloprid severely affect immunocompetence Osmia bicornis . In detail, males solutions 200 555...
Abstract In cases of acute intoxication, honeybees often lay in front their hives for several days, exposed to sunlight and weather, before a beekeeper can take sample. Beekeepers send samples analytical laboratories, but sometimes no residues be detected. Temperature sun light could influence the decrease pesticides bee thereby left analysis. Moreover, are usually sent via normal postal services without cooling. We investigated temporal dynamics whole-body imidacloprid live or dead...
Abstract Parkinson's disease (PD) is a movement disorder caused by the progressive loss of dopaminergic neurons. Natural antioxidants and plant extracts with neuroprotective properties offer promising new therapeutic approach for PD patients, but suitable large‐scale screening system required their discovery preclinical analysis. Here we used red flour beetle ( Tribolium castaneum ) as whole‐animal detection characterization substances. Paraquat was added to diet adult beetles induce PD‐like...
Wolbachia are widely distributed bacterial endosymbionts of arthropods and filarial nematodes. These bacteria can affect host fitness in a variety ways, such as protecting hosts against viruses other pathogens. Here, we investigate the possible role prevalence deformed wing virus (DWV), highly virulent pathogen honey bees (Apis mellifera) that is transmitted by parasitic Varroa mites (Varroa destructor). About 180 from 18 beehives were tested for infection with DWV. We first screened using...
The presence of farnesylated proteins at the inner nuclear membrane (INM), such as Lamins or Kugelkern in