A5025184608- Retinal Development and Disorders
- Visual perception and processing mechanisms
- Glaucoma and retinal disorders
- Neuroscience and Neuropharmacology Research
- Neural dynamics and brain function
- Photoreceptor and optogenetics research
- Retinal Diseases and Treatments
- Force Microscopy Techniques and Applications
- Lipid Membrane Structure and Behavior
- Marine Bivalve and Aquaculture Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Protein Structure and Dynamics
- Neurobiology and Insect Physiology Research
- Spectroscopy and Quantum Chemical Studies
- Morphological variations and asymmetry
- Marine and fisheries research
- Nanopore and Nanochannel Transport Studies
- Ophthalmology and Visual Impairment Studies
- Neuroscience and Neural Engineering
- Molecular Junctions and Nanostructures
- RNA Interference and Gene Delivery
- DNA and Nucleic Acid Chemistry
- Veterinary Medicine and Surgery
- Ocean Acidification Effects and Responses
- Retinopathy of Prematurity Studies
University of Edinburgh
1968-2023
University of Southampton
2009-2015
Rutherford Appleton Laboratory
2009-2012
King's College London
2009
Institut Laue-Langevin
2009
United States Military Academy
2008
University of Bath
2001-2002
Bangor University
1997-1999
Indiana University Bloomington
1997
Australian National University
1972-1992
A retinal ganglion cell distribution map has been prepared for the cresyl violet stained cat retina. It differs from previously published maps in revealing visual streak to be more substantial and showing a higher peak density of 9-10,000 cells/mm2 at presumed pole. The was used obtain minimum estimate population as 217,000 cells, than double total reported. problem classifying cells layer is discussed detail examples criterion illustrated. paper also includes an account mensuration...
A survey of diameter spectra in presented for classic neurones the cat retinal ganglion cell layer. From these, with aid retrograde HRP filling central retina, a set density distribution maps has been prepared each major modes neuronal spectrum. The total population classical neurones, presumed cells Hughes ('75), confirms published values minimum some 207,000 comprised 5,600 alpha mode, 80,700 beta and 120,700 gamma mode. proportion mode do not fill by transport from either optic nerve or...
This electron microscopic study indicates that the rabbit optic nerve contains 394,000 +/- 20,000 (p less than 0.05) fibers, of which at least 98% are myelinated. The fibre diameter spectrum is unimodal and ranges from 0.25-7 mum with its peak 0.75 mum. projection visual streak fibres not apparent in local spectra near head. Integration a ganglion cell density map retina another total count lying between 455,000 547,000. counts both substantially greater maximum previously reported.
Abstract The presence of a large population some 730,000 displaced amacrines is confirmed in the ganglion cell layer cat retina. These cells correspond to microneurons Hughes and Wieniawa‐Narkiewicz ( Nature 284 :468–470,'80) bar‐cells J. Comp. Neurol. 197 :303–339, '81): profiles which majority had previously been presumed be glia (Stone: Neurol 12 :337–352, '65; 180 :753–772, '78; Hughes: 163 :107–128, '75). A sample such nonganglion was identified by Nissl criteria an area retina...
Abstract An electron microscopic examination of two cat optic nerves indicates a mean total count 193,000 fibres ranging from 0.5μ to 13.5μin diameter. This count, although nearly double any previously reported, supports recent minimum estimates the retinal ganglion cell population eye. A radial gradient packing density exists across nerve close globe; high “core” with unimodal fibre diameter spectrum may be identified as area centralis outflow and peripheral low region trimodal contains...
Abstract The rabbit retinal ganglion cell layer contains a soma population which is morphologically distinct from the demonstrated cells. These “coronate cells” (Vaney, '80) have many features in common with classical neurons and are qualitatively different typical glial Detailed investigation by specific staining, ribonuclease treatment, electron microscopy indicates that coronate cells microneurons. contain somatic subsurface cisternae of amacrine cells, similar appearance to some layer....
A well distributed electron microscopic sample of 52,000 fibres from the pigmented rat optic nerve cross section indicates a total count 120,000 +/- 1,600 (S.E.M.) ranging 0.437 mu to 5.2 in diameter. The fibre diameter spectrum is essentially unimodal with peak at 1.0 developed "tail." These results are identical those available literature for albino rat.
Abstract A conscious rabbit which crouches in the ‘freeze’ position has an unequivocal 24° wide binocular field formed by overlap of two 12° sectors uniocular optical extend nasal its midline. Although this investigation reveals that horizontal representation visual cortical area I extends more than earlier reports, it is found to terminate at midline when eyes are set standard freeze position. The were not represented spite being served retina. posture thus appears have no I. Nevertheless,...
Abstract The neurons of the developing and adult ganglion cell layer cat retina may be morphologically divided into two major populations. One population, classic neurons, is mainly composed cells, a small percentage displaced amacrines, bar cells. remaining are microneurons, which make up majority amacrine population. loss cells during development has been attributed to death. It alternatively suggested that some lose their axon transformed without degeneration soma. Reexamination foetal...
Abstract The European native oyster ( Ostrea edulis ) is a threatened keystone species which historically created extensive, physically complex, biogenic habitats throughout seas. Overfishing and direct habitat destruction, subsequently compounded by pollution, invasive species, disease, predation climate change have resulted in the functional extinction of across much its former range. Although reef remains imperilled, active restoration efforts are rapidly gaining momentum. Identifying...
Abstract An improved flat‐mount procedure demonstrates that the developing ganglion cell layer of cat retina contains two morphologically distinct populations presumed neurons at all ages between embryonic day 36 (E36) and adulthood. One population resembles adult “classical neurons” composing cells bar‐cells Hughes, while remaining cells, which are smaller possess much less Nissl substance, presumably correspond to precursors microneurons. Although total neuron retinal remains quite...
The interaction of DNA with monolayers the cationic lipid dimethyldioctadecylammonium bromide, with/without 50 mol % a neutral "helper" lipid, either dioleoylphosphatidylethanolamine or cholesterol, has been studied using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. amount bound to head groups comprehensively quantified in range 8-39 vol% respect monolayer composition (monolayers composed bromide binding most containing least) pressure (DNA...