Events that overlap with previous experience may trigger reactivation of existing memories. However, such have different representational consequences within the hippocampal circuit. Computational theories function suggest dentate gyrus and CA 2,3 (DG/CA ) are biased to differentiate highly similar memories, whereas 1 integrate related events by representing them overlapping neural codes. Here, we tested whether formation differentiated or integrated representations in subfields depends on...

Neural circuitry in the medial temporal lobe (MTL) is critically involved mental time travel, which involves vivid retrieval of details past experience. Neuroscientific theories propose that MTL supports memory by retrieving previously encoded episodic information, as well reactivating a code specifying position particular event within an episode. However, neural computations supporting these abilities are underspecified. To test hypotheses regarding computational mechanisms supported...

Prior work has shown that the brain represents memories within a cognitive map supports inference about connections between individual related events. Real-world adaptive behavior is also supported by recognizing common structure among numerous distinct contexts; for example, based on prior experience with restaurants, when visiting new restaurant one can expect to first get table, then order, eat, and finally pay bill. We used neurocomputational approach examine how extracts uses abstract...

Studies have found that anterior temporal lobe (ATL) is critical for detailed knowledge of object categories, suggesting it has an important role in semantic memory. However, addition to information about entities, such as people and objects, memory also encompasses places. We tested predictions stemming from the PMAT model, which proposes there are distinct systems support different kinds knowledge: (AT) network, represents entities; a posterior medial (PM) used representational similarity...

Our understanding of the world is shaped by inferences about underlying structure. For example, at gym, you might notice that same people tend to arrive around time and infer they are friends work out together. Consistent with this idea, after participants presented a temporal sequence objects follows an community structure, biased from share properties. Here, we used fMRI measure neural representations structure learning examine how these support inference object relationships. We found...

Retrieved-context models of human memory propose that as material is studied, retrieval cues are constructed allow one to target particular aspects past experience. We examined the neural predictions these by using electrocorticographic/depth recordings and scalp electroencephalography (EEG) characterize category-specific oscillatory activity, while participants studied recalled items from distinct, neurally discriminable categories. During study, patterns predict whether a item will be...

Abstract Encoding an event that overlaps with a previous experience may involve reactivating existing memory and integrating it new information or suppressing the to promote formation of distinct, representation. We used fMRI during overlapping encoding track reactivation suppression individual, related memories. further model semantic knowledge based on Wikipedia quantify both integrated memories containing features events. Representational similarity analysis revealed prior in posterior...

The question of how knowledge structures, or schemas, are formed and they influence memory inference has posed long-standing challenges for cognitive scientists. Recent neuroscientific advances have improved our ability to quantify schemas as during their expression in novel situations, thus improving mechanistic understanding role cognition. Here, we review recent evidence indicating that bidirectional interactions between the hippocampus medial prefrontal cortex (mPFC) mediate schema...

Introduction. An influential theory of schizophrenic deficits in executive function suggests that patients have difficulty maintaining and utilising an internal contextual representation, whose is to ensure stimuli are processed a task-appropriate manner. In basic research on episodic memory, retrieved-context theories propose representation critically involved memory search, facilitating the retrieval memories. This machinery thought give rise temporal organisation during free recall:...

Abstract Several prominent theories posit that information about recent experiences lingers in the brain and organizes memories for current experiences, by forming a temporal context is linked to those at encoding. According these theories, if thoughts preceding an experience X resemble Y, then Y should show elevated probability of being recalled together. We tested this prediction using multi-voxel pattern analysis (MVPA) fMRI data measure neural evidence lingering processing stimuli. As...

Research on human memory has been strongly influenced by data from free recall experiments, wherein participants study a list of items (such as words) and then freely them in any order they wish (Murdock, 1962).Free provides an extremely rich dataset that not only reflects which were recalled but also the recalled.However, analysis is difficult, many different influences must be taken into account.For example, one influential analysis, conditional response probability function lag (lag-CRP),...

Abstract Our understanding of the world is shaped by inferences about underlying structure. For example, at gym, you might notice that same people tend to arrive around time and infer they are friends work out together. Consistent with this idea, after participants presented a temporal sequence objects follows an community structure, biased from share properties. Here, we used fMRI measure neural representations structure learning examine how these support inference object relationships. We...