A5063816508- Probabilistic and Robust Engineering Design
- Mathematical Approximation and Integration
- Scientific Research and Discoveries
- Wind and Air Flow Studies
- Reproductive System and Pregnancy
- Reproductive Physiology in Livestock
- Mathematical functions and polynomials
- Electromagnetic Scattering and Analysis
- Matrix Theory and Algorithms
- Digestive system and related health
- Immune Response and Inflammation
- Pregnancy and preeclampsia studies
- Lipid Membrane Structure and Behavior
- Fatigue and fracture mechanics
- Effects of Environmental Stressors on Livestock
- Computational Fluid Dynamics and Aerodynamics
- Air Quality Monitoring and Forecasting
- Cell Adhesion Molecules Research
- Sphingolipid Metabolism and Signaling
- Genetic and phenotypic traits in livestock
- Adipose Tissue and Metabolism
- Markov Chains and Monte Carlo Methods
- Immune Cell Function and Interaction
- Animal health and immunology
- Neonatal Respiratory Health Research
Bulgarian Academy of Sciences
2015-2025
Institute of Information and Communication Technologies
2015-2025
Institute of Mathematics and Informatics
2021-2023
University of Forestry
2022
Sofia University "St. Kliment Ohridski"
2022
Technical University of Sofia
2022
Institute of Biophysics and Biomedical Engineering
2013-2016
Institute for Parallel Processing
2007-2014
Institute of Biology and Immunology of Reproduction
1984-2010
PROBLEM: Recurrent spontaneous abortion (RSA) is a common complication of pregnancy for which there no known cure. Therefore, effective treatment needed. Published results from controlled clinical trials allogeneic leukocyte immunization women suffering RSA have given conflicting results. To address this controversy, the international raw data all patients who had been entered into that included control group were collected and analyzed. The primary question to be answered was whether...
Many important practical problems connected to energy efficiency in buildings, ecology, metallurgy, the development of wireless communication systems, optimization radar technology, quantum computing, pharmacology, and seismology are described by large-scale mathematical models that typically represented systems partial differential equations. Such often involve numerous input parameters. It is crucial understand how susceptible solutions uncontrolled variations or uncertainties within these...
Abstract The influence of emission levels on the concentrations four important air pollutants (ammonia, ozone, ammonium sulphate and nitrate) over three European cities (Milan, Manchester, Edinburgh) with different geographical locations is considered. Sensitivity analysis output Unified Danish Eulerian Model according to provided. Sobol’ variance-based approach for global sensitivity has been applied compute corresponding measures. To measure variation indices are estimated using efficient...
A new approach for Sensitivity Analysis (SA) in the field of air pollution modelling is proposed and applied to Unified Danish Eulerian Model (UNI-DEM), a large-scale model. The SA requires numerous model experiments with different values studied parameters. By simultaneous variation these parameters we produce set multidimensional discrete functions. These huge computational tasks require extensive resources storage CPU time. highly parallel implementation UNI-DEM has been created this...
Problem We evaluated implantation‐associated quantitative changes in endometrial and peripheral natural killer (NK)‐cell populations of pigs. Method study Natural cell were investigated 10, 15, 20, 30 40 days pregnant non‐pregnant (NP) sows by flow cytometry, immunohistochemistry morphometry. Results The number CD16 + NK cells significantly declined at attachment phase implantation remained relatively low over the course implantation. situ showed implantation‐phase dependent density...
We assessed implantation-associated quantitative changes in peripheral blood and endometrial T lymphocytes throughout epitheliochorial placenta formation.T-cell subsets were investigated 10-, 15-, 20-, 30-, 40-day pregnant non-pregnant sows by flow cytometry immunohistochemistry.Endometrial total T, cytotoxic (Tc), helper (Th) cells peak numbers at the attachment phase of implantation Tc persisted high proportions up to placental establishment. The number gammadelta was relatively small...
A 3‐stage sensitivity analysis approach, based on of variances technique for calculating Sobol's global indices and computationaly efficient Monte Carlo integration techniques is considered applied to a large‐scale air pollurion model, the Danish Eulerian Model. On first stage it necessary carry out set computationally expensive numerical experiments extract data. The output used construct mesh‐functions ozone concentration ratios be in next stages evaluating variances. Here we use specially...
Vesicle cycling, which is an important biological event, involves the interplay between membrane lipids and proteins, among enzyme phospholipase A2 (PLA2) plays a critical role. The capacity of PLA2 to trigger budding fission liquid-ordered (L(o)) domains has been examined in palmitoyl-docosahexaenoylphosphatidylcholine (PDPC) palmitoyl-oleoylphosphatidylcholine (POPC)/sphingomyelin/cholesterol membranes. They both exhibited L(o)/liquid-disordered (L(d)) phase separation. We demonstrated...