A5101468910- Musculoskeletal pain and rehabilitation
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Spine and Intervertebral Disc Pathology
- Muscle activation and electromyography studies
- Esophageal and GI Pathology
- Radiomics and Machine Learning in Medical Imaging
- Veterinary Orthopedics and Neurology
- Bone fractures and treatments
- Hernia repair and management
- Knee injuries and reconstruction techniques
- Lung Cancer Diagnosis and Treatment
- Pelvic and Acetabular Injuries
- Colorectal Cancer Screening and Detection
- Wound Healing and Treatments
- Total Knee Arthroplasty Outcomes
- Corneal surgery and disorders
- Surgical Sutures and Adhesives
- Musculoskeletal Disorders and Rehabilitation
- Shoulder Injury and Treatment
- Gallbladder and Bile Duct Disorders
- Sports injuries and prevention
- Breast Cancer Treatment Studies
- Pleural and Pulmonary Diseases
- Biliary and Gastrointestinal Fistulas
Chengdu University of Traditional Chinese Medicine
2025
Affiliated Hospital of Qingdao University
2015-2024
Qingdao University
2010-2024
Lianyungang Maternal and Children’s Hospital
2021-2024
Xuzhou Central Hospital
2023-2024
University of Liverpool
2024
Ruijin Hospital
2023
Shanghai Jiao Tong University
2023
Zhongda Hospital Southeast University
2019
University of Colorado Denver
2007-2012
Abstract When skin trauma occurs, rapid achievement of the post‐wound closure is required to prevent microbial invasion, inhibit scar formation and promote wound healing. To develop a dressing for accelerating post‐wound‐closure healing, thermo‐responsive tissue‐adhesive hydrogel with interpenetrating polymer networks (IPN) fabricated based on N ‐dimethylbisacrylamide (NIPAM) glutaraldehyde (GTA) cross‐linked hyaluronic acid (HA). Results not only confirm thermo‐stimulated self‐contraction...
Superbacteria-induced skin wound infections are huge health challenges, resulting in significant financial and medical costs due to notable morbidity mortality worldwide. Probiotics found the effective treating bacterial infection, moderating microbial dysbiosis inflammation induced by pathogens, regulating immune system, as well even promoting tissue repair. However, improving their colonization efficiency viability remains a large obstacle for proper applications. Inspired probiotic...
Study Design. Electrical and mechanical stimulation of the lumbar supraspinous ligament three patients with L4-L5 spinal deficits feline model, respectively, was applied while recording electromyography on multifidus muscles. Objectives. To determine if mechanoreceptors in human spine can reflexively recruit muscle force to stabilize spine, demonstrate, that such ligamento-muscular synergy is elicited by deformation (and possibly other ligaments), facet joint capsule, disc. Summary...
The anterior-posterior displacement and rotation of the tibia elicited by isolated loading quadriceps mus cle was determined as a function joint angle muscle load using computerized radiographic tech nique. Data collected from 12 fresh-frozen cadaveric knees demonstrated that contraction can result in significant (<7 mm) anterior range 0° to 80° flexion, mild (<2 posterior 120° flexion. Peak 6.3 mm observed at 30° flexion under kg quadriceps, while constant 1.5 throughout angles...
Study Design. The recording of electromyographic responses from the in vivo lumbar multifidus cat, obtained while cyclic loading was applied as occupational bending/lifting motion over time. Objectives. To determine whether effectiveness stabilizing reflexive muscular activity diminishes during prolonged activity; recovery lost muscle by a 10-minute rest; and such diminished is caused fatigue, neurologic habituation, or desensitization mechanoreceptors spinal viscoelastic tissues resulting...
Abstract Developing bio‐multifunctional patches with natural extracellular matrix‐like structures, excellent high adhesion in the wet state, self‐healing ability, antibacterial activity, and favorable cell responses for accelerating tissue healing is highly desirable clinical applications. Herein, composite hydrogels are developed by coupling carboxymethyl chitosan 4‐arm poly (ethylene glycol) aldehyde full‐thickness abdominal wall defect repair. The prepared exhibit mechanical properties,...
Clinical tissue adhesives remain some critical drawbacks for managing emergency injuries, such as inadequate adhesive strength and insufficient anti-infection ability. Herein, a novel, self-healing, antibacterial carboxymethyl chitosan/polyaldehyde dextran (CMCS/PD) hydrogel is designed the first-aid effective trauma management. We examined gel-forming time, porosity, properties, cytotoxicity, strength, hemocompatibility. Liver hemorrhage, tail severance, skin wound infection models of rats...
Transmembrane topology of most eukaryotic polytopic proteins is established cotranslationally at the endoplasmic reticulum membrane through action alternating signal and stop transfer sequences. Here we demonstrate that cystic fibrosis transmembrane conductance regulator (CFTR) achieves its N terminus a variation this mechanism involves both co- posttranslational translocation events. Using series defined chimeric truncated expressed in reticulocyte lysate system, have identified two...
Tourette syndrome (TS) is a neuropsychiatric disorder characterized by chronic motor and phonic tics, with higher prevalence among boys. This condition can significantly impact patients' learning daily life. Due to the limited efficacy potential side effects of pharmacological treatments for TS, there critical need develop novel, tailored therapeutic strategies. Repetitive transcranial magnetic stimulation (rTMS) direct current (tDCS) have been proposed as shown promising results. Here, we...
Alternative splicing is a major mechanism of controlling gene expression and protein diversity in higher eukaryotes. We report that the factor SRSF10 functions during striated muscle development, myoblast differentiation, glucose production both cells mice. A combination RNA-sequencing molecular analysis allowed us to identify muscle-specific events controlled by are critically involved development. Inclusion alternative exons 16 17 Lrrfip1 event activated essential for differentiation. On...
Study Design. Electromyographic responses from the lumbar multifidus muscle of cat were recorded in vivo during 50 minutes cyclic loading followed by 2 hours rest. Objective. To determine rate recovery reflexive muscular stabilizing activity resulting rest after viscoelastic laxity induced loading. Summary Background Data. Muscular forces agonists and antagonists repeatedly shown to be most significant structures spine. Reflexive coactivation force elicited mechanoreceptors spinal were,...
Abstract Occupations requiring frequent periods of static lumbar flexion are known epidemiologically to be risk factors for the development cumulative low back disorder. The impact load magnitude sustained during a series short flexions followed by an equally long rest period on disorder was addressed in vivo feline model. Static loads 20, 40, and 60 N were applied over 10 min 10‐min sessions that repeated six times (for total 2 h) while monitoring viscoelastic creep (laxity) reflex...
Presurgical computed tomography (CT)-guided localization is frequently employed to reduce the thoracotomy conversion rate, while increasing rate of successful sublobar resection ground glass nodules (GGNs) via video-assisted thoracoscopic surgery (VATS). In this study, we compared clinical efficacies presurgical CT-guided hook-wire and indocyanine green (IG)-based GGNs.
Background Cyclic load applied to various joints during occupational and sports activities is epidemiologically linked higher risk of neuromuscular disorder development. Hypothesis Passive cyclic loading the knee will develop laxity creep in anterior cruciate ligament, these may elicit a quadriceps hamstrings. Women be more susceptible disorder. Study Design Controlled laboratory study. Methods Male female groups were subjected 10 minutes passive (0.1 Hz) at mild (150-200 N) 35° 90° flexion....
In Brief Study Design. Biomechanical and radiographical study. Objective. To test the hypothesis that stiffness strength at discrete sites of human lumbar vertebrae depend on 3-dimentional structure density vertebral-body bone elements, can be evaluated using models based vertebral characteristics obtained from quantitative computed tomogrphy. Summary Background Data. We have not found published methods allow in vivo evaluation mechanical properties body applicable for clinical use....
The biomechanical basis for the treatment of delayed union tibial fractures by partial fibulectomy has yet to be fully evaluated. To gain further insight into this problem, nine intact cadaveric lower extremities were instrumented with strain gauges on surfaces tibia and fibula. limbs then subjected axial loading ankle subtalar joints placed in multiple positions. specimens loaded either through distal femur or direct plateau. All first tested after sectioning interosseous membrane finally...