A5084425768- Salmonella and Campylobacter epidemiology
- Global Cancer Incidence and Screening
- Food Safety and Hygiene
- Listeria monocytogenes in Food Safety
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- RNA modifications and cancer
- Cancer Risks and Factors
- RNA Interference and Gene Delivery
- Viral gastroenteritis research and epidemiology
- Health disparities and outcomes
- Pancreatic and Hepatic Oncology Research
- Cancer Genomics and Diagnostics
- Cervical Cancer and HPV Research
- Colorectal Cancer Screening and Detection
- Breast Cancer Treatment Studies
- Hepatitis B Virus Studies
- Cancer, Hypoxia, and Metabolism
- Health, Environment, Cognitive Aging
- Head and Neck Cancer Studies
- ATP Synthase and ATPases Research
- BRCA gene mutations in cancer
- Radiomics and Machine Learning in Medical Imaging
- Molecular Biology Techniques and Applications
- Alcohol Consumption and Health Effects
National Cancer Institute
2013-2024
Cancer Research Center
2011-2023
National Institutes of Health
2011-2022
National Heart Lung and Blood Institute
2017-2022
New York State Psychiatric Institute
2022
National Institute on Drug Abuse
2011-2022
Albert Einstein College of Medicine
2020
United States Census Bureau
2020
University of Iowa
2011-2017
GTx (United States)
2017
Recent increases in incidence and survival of oropharyngeal cancers the United States have been attributed to human papillomavirus (HPV) infection, but empirical evidence is lacking.
Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide. Incidence rates are increasing in United States. Monitoring incidence, survival, and within at-risk populations can facilitate control efforts.Age-adjusted incidence trends for HCC were examined Surveillance, Epidemiology, End Results (SEER) registries from 1975 to 2005. Age-specific birth cohorts born between 1900 1959. Age-adjusted cause-specific survival 1992 2005 SEER 13 by race/ethnicity, stage,...
In 2010, Surveillance, Epidemiology, and End Results (SEER) registries began collecting human epidermal growth factor 2 (HER2) receptor status for breast cancer cases. Breast subtypes defined by joint hormone (HR; estrogen [ER] progesterone [PR]) HER2 were assessed across the 28% of US population that is covered SEER registries. Age-specific incidence rates subtype calculated non-Hispanic (NH) white, NH black, Asian Pacific Islander (API), Hispanic women. Joint HR/HER2 distributions age,...
This report provides an overview of current childhood cancer statistics to facilitate analysis the impact past research discoveries on outcome and provide essential information for prioritizing future directions.Incidence survival data cancers came from Surveillance, Epidemiology, End Results 9 (SEER 9) registries, mortality were based deaths in United States that reported by states Centers Disease Control Prevention underlying cause.Childhood incidence rates increased significantly 1975...
BACKGROUND Annual updates on cancer occurrence and trends in the United States are provided through an ongoing collaboration among American Cancer Society (ACS), Centers for Disease Control Prevention (CDC), National Institute (NCI), North Association of Central Registries (NAACCR). This annual report highlights increasing burden liver intrahepatic bile duct (liver) cancers. METHODS incidence data were obtained from CDC, NCI, NAACCR; about deaths CDC's Center Health Statistics (NCHS)....
This study sought to determine the prevaccine type-specific prevalence of human papillomavirus (HPV)–associated cancers in United States evaluate potential impact HPV types current and newly approved 9-valent vaccines. The Centers for Disease Control Prevention partnered with seven US population-based cancer registries obtain archival tissue diagnosed from 1993 2005. testing was performed on 2670 case patients that were fairly representative all participating registry cases by age sex....
Vibrio parahaemolyticus infections are associated with consumption of raw or undercooked shellfish, contaminated food, and exposure wounds to warm seawater. Foodborne outbreaks sporadic from species in 4 Gulf Coast states reported routinely the Centers for Disease Control Prevention (CDC). Between 1988 1997, 345 V. were reported: 59% gastroenteritis, 34% wound infections, 5% septicemia, 2% other exposures. Forty-five percent patients suffering these conditions hospitalized their 88% persons...
BACKGROUND To evaluate whether progress continues in identifying more effective treatments for children and adolescents with cancer, the authors examined both overall disease‐specific childhood cancer mortality rates United States, focusing on data from 2000 to 2010. METHODS Age‐adjusted US trends 1975 2010 were estimated using joinpoint regression analysis. Analyses of annual percentage change (APC) performed same diagnostic groupings period restricted through ages <20 years, <15 15...
Hepatocellular carcinoma (HCC) incidence rates have been increasing in the United States for past 35 years. Because HCC has a poor prognosis, quantitative forecasts could help to inform prevention and treatment strategies reduce burden of HCC.
The objectives were to describe Surveillance, Epidemiology and End Results (SEER) hepatocellular carcinoma (HCC) incidence trends the US liver cancer mortality by geography, age, race/ethnicity, gender.
Background: Cancers are heterogeneous, comprising distinct tumor subtypes. Therefore, presenting the burden of cancer in population and trends over time by these subtypes is important to identify patterns differences occurrence subtypes, especially generalize findings U.S. general population.Methods: Using SEER Cancer Registry Data, we present incidence rates according for diagnosis years (1992-2013) among men women five major sites: breast (female only), esophagus, kidney renal pelvis, lung...
BACKGROUND Hepatocellular carcinoma (HCC) incidence has been increasing in the United States for several decades; and, as of hepatitis C virus (HCV) infection declines and prevalence metabolic disorders rises, proportion HCC attributable to various risk factors may be changing. METHODS Data from Surveillance, Epidemiology, End Results‐Medicare linkage were used calculate population fractions (PAFs) each factor over time. Patients with (n = 10,708) who diagnosed during years 2000 through 2011...
Approaches to the diagnosis and management of hepatocellular carcinoma (HCC) are improving survival. In Surveillance, Epidemiology, End Results-13 registries, HCC stage, histological confirmation, first-course surgery were examined. Among 21,390 cases diagnosed with follow-up vital status during 1998-2008, there 4,727 (22%) reported invasive liver surgery, local tumor destruction, or both. The proportion ablation was 39% among localized stage only 4% distant/unstaged cases. Though 70% had...
PURPOSE Recent increases in incidence and survival of oropharyngeal cancers the United States have been attributed to human papillomavirus (HPV) infection, but empirical evidence is lacking. PATIENTS AND METHODS HPV status was determined for all 271 (1984-2004) collected by three population-based cancer registries Surveillance, Epidemiology, End Results (SEER) Residual Tissue Repositories Program using polymerase chain reaction genotyping (Inno-LiPA), HPV16 viral load, mRNA expression....
Understanding relationships between individual-level demographic, socioeconomic status (SES) and U.S. opioid fatalities can inform interventions in response to this crisis.The Mortality Disparities American Community Study (MDAC) links nearly 4 million 2008 Survey responses the 2008-2015 National Death Index. Univariate multivariable models were used estimate overdose fatality hazard ratios (HR) 95% confidence intervals (CI).Opioid was an overrepresented cause of death among people 10 59...
Intrahepatic (ICC) and extrahepatic (ECC) cholangiocarcinomas are rare tumors that arise from the epithelial cells of bile ducts, etiology both cancer types is poorly understood. Thus, we utilized Surveillance, Epidemiology, End Results (SEER)-Medicare resource to examine risk factors novel preexisting medical conditions may be associated with these types.Between 2000 2011, 2,092 ICC 2,981 ECC cases 323,615 controls were identified using SEER-Medicare database. Logistic regression was used...
In the United States, hepatocellular carcinoma (HCC) survival varies with tumor characteristics, patient comorbidities, and treatment. The effect of HCC etiology on is less clearly defined. relationship between mortality was examined using Surveillance, Epidemiology, End Results-Medicare data. a cohort 11,522 cases diagnosed from 2000 through 2014, etiologies were identified Medicare data, including metabolic disorders (32.9%), hepatitis C virus (8.2%), alcohol (4.7%), B (HBV, 2.1%), rare...
Area-level measures are often used to approximate socioeconomic status (SES) when individual-level data not available. However, no national studies have examined the validity of these in approximating SES.Data came from ~ 3,471,000 participants Mortality Disparities American Communities study, which links 2008 Community Survey National Death Index (through 2015). We calculated correlations, specificity, sensitivity, and odds ratios summarize concordance between individual-, census tract-,...
Abstract Salmonella enterica serotype Enteritidis emerged as an important illness during the 1980s. Investigations showed that consumption of undercooked eggs was major risk factor for disease, and a variety prevention control efforts were initiated 1990s. We describe sporadic infections outbreaks S. in United States from 1985 through 1999 discuss efforts. After reaching high 3.9 per 100,000 population 1995, declined to 1.98 1999. While total number decreased by half, those western states...
Vibrio vulnificus infections are highly lethal and associated with consumption of raw shellfish exposure wounds to seawater. V. were reported the Centers for Disease Control Prevention from 23 states. For primary septicemia infections, oyster trace-backs performed water temperature data obtained at harvesting sites. Between 1988 1996, 422 reported; 45% wound 43% septicemia, 5% gastroenteritis, 7% undetermined exposure. Eighty-six percent patients male, 96% consumed oysters. Sixty-one died;...