A5085130573- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Reconstructive Surgery and Microvascular Techniques
- Spinal Dysraphism and Malformations
- Traumatic Ocular and Foreign Body Injuries
- Tracheal and airway disorders
- Cerebrospinal fluid and hydrocephalus
- Trauma Management and Diagnosis
- Bone Tumor Diagnosis and Treatments
- Teratomas and Epidermoid Cysts
- Oral and Maxillofacial Pathology
- Congenital limb and hand anomalies
- Cancer and Skin Lesions
- Head and Neck Surgical Oncology
- Anatomy and Medical Technology
- Gun Ownership and Violence Research
- Sarcoma Diagnosis and Treatment
- Connective tissue disorders research
- Ear and Head Tumors
- Facial Nerve Paralysis Treatment and Research
- Rabies epidemiology and control
- Soft tissue tumor case studies
- Hedgehog Signaling Pathway Studies
- Head and Neck Cancer Studies
- Prenatal Screening and Diagnostics
Mountview Theatre School
2025
University of Missouri–Kansas City
2024
Virginia Commonwealth University
2013-2024
American Academy of Pediatrics
2024
Louisiana State University
2023
Virginia Commonwealth University Medical Center
2009-2022
Meharry Medical College
2022
Creative Commons
2022
Children's Hospital of Richmond at VCU
2013-2021
University of Virginia
2018
Orofacial clefts are common developmental disorders that pose significant clinical, economical and psychological problems. We conducted genome-wide association analyses for cleft palate only (CPO) lip with or without (CL/P) ~17 million markers in sub-Saharan Africans. After replication combined analyses, we identified novel loci CPO at near significance on chromosomes 2 (near CTNNA2) 19 SULT2A1). In situ hybridization of Sult2a1 mice showed expression SULT2A1 mesenchymal cells palate,...
OBJECTIVE This study examines a series of patients with hypophosphatemic rickets and craniosynostosis to characterize the clinical course associated craniofacial anomalies. METHODS A 20-year retrospective review identified secondary at 3 major centers. Parameters examined included sex, age diagnosis head shape anomaly, affected sutures, etiology rickets, presenting symptoms, number type surgical interventions, diagnoses. literature was performed optimize treatment recommendations. RESULTS...
In order to characterize the specificity of expression neurotransmitter biosynthetic gene dopamine beta-hydroxylase (DBH), identification proteins that interact with DB1 enhancer was initiated. A homeobox-containing cDNA isolated from a PC12 library screened enhancer. The homeodomain is member paired-like class, and encoded by several nonidentical cDNAs. cDNAs contain same sequence in 3′ coding noncoding sequences, but diverge 5′ homeodomain. This family named Arix. Arix mRNA transcripts are...
Background: Pfeiffer syndrome is rarely encountered, even at major craniofacial centers. Published reports indicate high mortality rates (25 to 85 percent) for severely affected subtypes. The authors reviewed their surgically treated patients improve outcomes. Methods: conducted a 17-year, single-center, retrospective outcome assessment of all children syndrome, with data summarized using descriptive statistics. Results: Of 802 craniosynostosis, 28 were identified syndrome: 17 classified as...
The Family First Prevention Services Act (FFPSA) allows states to use federal Title IV-E funds provide time-limited, clinically appropriate of congregate care, including Qualified Residential Treatment Programs (QRTPs), for youth in foster care. October 1, 2021 marked the deadline begin implementing these FFPSA care reforms. From June September 2022, we conducted a mixed-methods study obtain baseline understanding implementation barriers, successes, and recommendations inform policy practice.
The median-ulnar anastomosis (Martin-Gruber) of the forearm was present in 15% normal fetuses dissected. Among congenitally abnormal fetuses, all cases trisomy 21 had both forearms. is usually between anterior interosseous nerve and ulnar could be classified into six basic patterns.
Craniosynostosis affecting the lambdoid suture is uncommon. The definition of craniosynostosis solely applies to those cases demonstrating true obliteration, similar other forms craniosynostosis. In patients presenting with posterior plagiocephaly, must be differentiated from much more common positional molding. It can occur in a unilateral form, bilateral or as part complex children craniofacial syndromes, synostosis most often seen within context pansynostotic picture. Chiari malformations...
Children with craniosynostosis may require cranial vault remodeling to prevent or relieve elevated intracranial pressure and correct the underlying craniofacial abnormalities. The procedure is typically associated significant blood loss high transfusion rates. risks transfusions are well documented include transmission of infectious agents, bacterial contamination, acute hemolytic reactions, transfusion-related lung injury, immune modulation. This study presents Children's Hospital Richmond...
Background: The complex craniosynostoses, which include all nonsyndromic multiple sutural fusions, represent a small fraction of patients presenting with craniosynostosis. Among these are trisutural fusion, dubbed the "Mercedes Benz pattern," involving sagittal and both lambdoid sutures. purpose this report is to review authors' series unusual form craniosynostosis, identify associated anomalies, assess treatment outcomes. Methods: authors conduced retrospective clinical outcome assessment...
Abdominal wall reconstruction after the separation of omphalopagus conjoined twins poses a challenge for reconstructive surgeon as often results in large defects involving both skin and abdominal wall. We describe fabrication multicomponent medical model devised to simulate various soft tissue elements enhance presurgical planning capabilities. A life-size was cast including circumferential rendition lower thorax abdomen. The consisted foam core simulating density with silicone rubber skin....
With the limitations of work hour restrictions and legal liability surgical resident's operative experience is declining. We sought to find other methods training using tactile simulations for plastic surgery. collaborative efforts a local artist, flap trainer was designed simulate natural properties, layers, interaction between layers tissue. A session held with Plastic Surgery faculty, residents, students review practice flaps trainer. Afterward, participants filled out survey evaluating...
A mature cystic teratoma is a mass with heterogeneous appearance, consisting of adult tissue two or three layers: endoderm, mesoderm, and ectoderm. It rare, benign transformation somatic most commonly found in the sacrococcygeal region may resemble an uncomplicated spina bifida on prenatal ultrasonography. In this case report, we describe female newborn extremely rare thoracolumbar region. She presented prenatally preliminary diagnosis meningomyelocele, diastematomyelia, Chiari II...
Dog bite injuries cause significant preventable patient morbidity and health care expenditure in children. This study aimed to characterize the healthcare burden related pediatric dog at a level 1 trauma center.This is retrospective review of 356 patients who presented Virginia Commonwealth University Pediatric Emergency Department between July 2007 August 2017 after sustaining injuries. Demographic information, injury details, management, outcomes, financial information were analyzed.Most...
Total parenteral nutrition (TPN) can be a lifesaving intervention for premature neonates and it is often delivered through peripheral access in this unique population. However, extravasation tissue damage result. Current literature lacks strong evidence regarding the treatment reconstruction of such injuries age group. The authors present patient with 30-week gestational newborn whom suffered an injury peripherally administered TPN leading to full thickness skin soft necrosis dorsum right...