A5091466039- Microbial Metabolic Engineering and Bioproduction
- Biofuel production and bioconversion
- Enzyme Production and Characterization
- Bacterial Genetics and Biotechnology
- Peripheral Artery Disease Management
- biodegradable polymer synthesis and properties
- Muscle Physiology and Disorders
- Antiplatelet Therapy and Cardiovascular Diseases
- Enzyme Catalysis and Immobilization
- Protease and Inhibitor Mechanisms
- Gene Regulatory Network Analysis
- Genomics and Phylogenetic Studies
University of Buenos Aires
2017-2022
Consejo Nacional de Investigaciones Científicas y Técnicas
2017-2022
Institute of Astronomy and Space Physics
2022
Fundación Ciencias Exactas y Naturales
2017-2022
ABSTRACT The microbial production of biofuels and other added-value chemicals is often limited by the intrinsic toxicity these compounds. phasin PhaP from soil bacterium Azotobacter sp. strain FA8 a polyhydroxyalkanoate granule-associated protein that protects recombinant Escherichia coli against several kinds stress. enhances growth poly(3-hydroxybutyrate) synthesis in polymer-producing strains reduces formation inclusion bodies during overproduction heterologous proteins. In this work,...
Manipulation of global regulators is one the strategies used for construction bacterial strains suitable synthesis bioproducts. However, pleiotropic effects these can vary under different conditions and are often strain dependent. This study analyzed ArcA, CreC, Cra, Rob using single deletion mutants well-characterized completely sequenced Escherichia coli BW25113. Comparison each regulator on major extracellular metabolites, tolerance to several compounds, native nonnative bioproducts...
Thermoanaerobacterium thermosaccharolyticum GSU5 was isolated from animal dung collected in a pasture plain Buenos Aires, Argentina. This thermophilic and anaerobic microorganism able to produce butanol ethanol, but not acetone, using sugars such as xylose, arabinose, glucose, galactose, fructose, sucrose, cellobiose. Key metabolic enzymes leading solvent production were identified its genome. A detailed analysis of the organic acid biosynthetic pathway genes sequenced strains revealed new...
Poly(amide-triazole) and poly(ester-triazole) synthesized from d-galactose as a renewable resource were applied for the synthesis of nanoparticles (NPs) by emulsification/solvent evaporation method. The NPs characterized stable, spherical particles, none their components, including stabilizer poly(vinyl alcohol), cytotoxic normal rat kidney cells. These proved to be useful efficient encapsulation cilostazol (CLZ), an antiplatelet vasodilator drug currently used treatment intermittent...