- Pharmaceutical Practices and Patient Outcomes
- Lipoproteins and Cardiovascular Health
- Pharmaceutical studies and practices
- Pharmacovigilance and Adverse Drug Reactions
- Pharmacological Effects and Toxicity Studies
- Health Systems, Economic Evaluations, Quality of Life
- Epilepsy research and treatment
- Patient Safety and Medication Errors
- Chronic Kidney Disease and Diabetes
- Schizophrenia research and treatment
- Pregnancy and Medication Impact
- Bipolar Disorder and Treatment
- Electroconvulsive Therapy Studies
- Diabetes Treatment and Management
- Atrial Fibrillation Management and Outcomes
- Electrolyte and hormonal disorders
- Hemoglobinopathies and Related Disorders
- Psoriasis: Treatment and Pathogenesis
- Rheumatoid Arthritis Research and Therapies
- Medication Adherence and Compliance
- Autoimmune and Inflammatory Disorders Research
- Pregnancy and preeclampsia studies
- Autoimmune Bullous Skin Diseases
- Erythropoietin and Anemia Treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
Karolinska Institutet
2021-2025
Institute of Engineering
2025
NFC Institute of Engineering and Technology
2025
Luigi Sacco Hospital
2018-2021
Prince Sultan Military College of Health Sciences
2016-2020
Taylor's University
2020
Iqra University
2020
King Fahd Military Medical Complex
2016-2020
University of Milan
2019-2020
SUNY Downstate Health Sciences University
2020
The COVID-19 pandemic has had a remarkable economic impact worldwide, including in Pakistan, and was soon declared an international public health issue. education sector specifically school (K-12) education, seen staggering due to obstacles delivering alternative forms of during the pandemic. Educational institutions Pakistan closed on March 13, 2020, then, April Ministry Education, collaboration with Information Broadcasting Ministry, announced launch “tele-schooling” initiative. Teaching...
The burden and outcomes of inflammation in patients with atherosclerotic cardiovascular disease (ASCVD) are not well defined beyond the controlled settings trials research cohorts.
Abstract Background Health-related quality of life (HRQoL) is considered to be the fourth 90 UNAIDS 90-90-90 target monitor effects combination antiretroviral therapy (ART). ART has significantly increased expectancy people living with HIV/AIDS (PLWHA). However, impact chronic infection on HRQoL remains unclear, while factors influencing may vary from one country another. The current study aimed assess and its associated among PLWHA receiving in Pakistan. Methods A cross-sectional...
Background The effectiveness of lipid-lowering therapy (LLT) is affected by both intensity and adherence. This study evaluated the associations LLT intensity, adherence, combination these 2 aspects management with risk major adverse cardiovascular events (MACE) in people coronary heart disease. Methods Results an observational all adults who suffered a myocardial infarction or had revascularization during 2012 to 2018 initiated Stockholm, Sweden. Study exposures were adherence (proportion...
Studies in patients with immune-mediated inflammatory diseases (IMIDs) have inconsistently suggested that anti-TNFα therapy may be associated excessive weight gain.We performed a nested case/non-case analysis to investigate the anti-TNF-α inhibitor-associated body-changes US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database. The risk was expressed as measure of disproportionality using reporting odds ratio (ROR) while adjusting for sex, drugs known cause gain...
It is unknown whether initiating diuretics on top of renin-angiotensin system inhibitors (RASi) superior to alternative antihypertensive agents such as calcium channel blockers (CCBs) in patients with chronic kidney disease (CKD). For this purpose, we emulated a target trial the Swedish Renal Registry 2007-2022 that included nephrologist-referred moderate-advanced CKD and treated RASi, who initiated or CCB. Using propensity score-weighted cause-specific Cox regression, compared risks major...
Skin cancer (SC) is a highly serious kind of that, if not addressed swiftly, might result in the patient’s demise. Early detection this condition allows for more effective therapy and prevents disease development. Deep Learning (DL) approaches may be used as an efficient tool SC (SCD). Several DL-based algorithms automated SCD have been reported. However, models are needed to improve accuracy. As result, paper introduces new strategy based on Grey Wolf optimization (GWO) methodologies CNN....
Abstract Background and hypothesis A more pronounced short-term increase in single-kidney GFR (ΔskGFR) has been associated with better long-term kidney function living donors. Whether this also applies to non-donors is unknown. We evaluated if ΔskGFR risk of eGFR decline individuals undergoing unilateral nephrectomy. Methods This study included 1777 participants from the SCREAM cohort who underwent radical nephrectomy Stockholm between 2006–2021. The was calculated as early (1–6 months)...
Expanding extensive and intricate social networks has required sophisticated community detection techniques. This study presents an innovative hybrid methodology that utilizes node space similarity local knowledge to enhance identification. Node is defined by integrating eigenvector centrality (EC), which quantifies a node’s influence inside the network, with proximity metrics, such as closeness, evaluate connectivity between nodes. enables us identify cohorts of individuals analogous...
Quality registries may involve specific inclusion criteria, detailed investigations or selected hospitals and practitioners, which are not random. Whether the care outcomes in quality generalizable to broader population is well known. We here examine indicators heart failure (HF) patients enrolled vs. non-enrolled Swedish Heart Failure (SwedeHF) registry. Observational study of 90-day survivors after a HF Stockholm (2012-2021). linked health records from Creatinine Measurements (SCREAM)...
Abstract Background: Oxidative stress plays a key role in the pathogenesis of epilepsy and contributes underlying epileptogenesis process. Anticonvulsant drugs targeting oxidative domain may provide better control seizure. The present study was carried out to investigate effect clinically used anti-epileptic (AEDs) on course pentylenetetrazole (PTZ)-induced kindling markers mice. Methods: Six mechanistically heterogeneous anticonvulsants: phenobarbital, phenytoin, levetiracetam, pregabalin,...
Background: Medication reconciliation is a major component of safe patient care. One the main problems in implementation medication process lack human resources. With limited resources, it better to target resources patients who will derive most benefit from it.Objective: The primary objective this study was determine frequency and types errors identified by pharmacists performing at admission. Each error rated for its potential cause harm during hospitalization. A secondary risk factors...
To characterize adverse reactions associated with medication errors (ME) reported in US Food and Drug Administration Adverse Event Reporting System (US-FAERS), to identify the potential signals of disproportionate reporting (SDR) for different drugs.ME Individual Case Study Report (ICSRs) were identified. ICSRs categorized by patient age groups, affected stages process Anatomical Therapeutic Chemical classification system. Disproportionality analyses performed groups.46,8677 retrieved. An...
Objectives: To examine the signals of bullous pemphigoid (BP) with dipeptidyl peptidase-4 inhibitors (DPP-4i) in VigiBase® and potential role their pharmacodynamic/pharmacokinetic parameters occurrence BP. Methods: Case/non-case analyses were performed to signal BP [reporting odds ratio (ROR)] for gliptins. Secondly, authors linear regression explore association between DPP-4i affinities toward different target enzymes (DPP-2, DPP-4, DPP-8, DPP-9) volume distribution (Vd). Results: A...
Abstract Background Glyco-metabolic deteriorations are the most limiting adverse reactions to antipsychotics in long term. They have been incompletely investigated and properties of that determine their magnitude not clarified. To rank by glyco-metabolic alterations associate it pharmacological chemical properties, we conducted a network meta-analysis. Methods We searched PubMed, Embase, Psycinfo on 10 September 2020. selected studies containing endpoint-baseline difference or distinct...