A5006627086- Radiation Detection and Scintillator Technologies
- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Radiation Therapy and Dosimetry
- CCD and CMOS Imaging Sensors
- Advanced Optical Sensing Technologies
- Smart Agriculture and AI
- Advanced Neural Network Applications
- Image Processing Techniques and Applications
- Paleontology and Stratigraphy of Fossils
- Methane Hydrates and Related Phenomena
- Particle Detector Development and Performance
- Hydrocarbon exploration and reservoir analysis
University of Bristol
2019-2023
Monolithic active pixel sensor (MAPS) devices are an effective tool for upstream verification of intensity-modulated radiotherapy (IMRT) treatments. It is crucial to measure with high precision the positions multi-leaf collimators (MLCs) used shape beam in real time, order enhance quality and safety This article describes r-UNet, a deep learning-based solution leaf position reconstruction. The model analyze high-resolution images produced by Lassena MAPS device automatically determine...
Multileaf collimators (MLCs) are an essential component in modern radiotherapy that shape the X-ray treatment beam. Currently, MLC leaf position accuracy is verified to ±1 mm every month. However, can drift between verification dates and only occurs pretreatment. To prevent serious errors, it would be highly beneficial use a real-time system. We developing system based on monolithic active pixel sensors (MAPSs). MAPS radiation hard under photon electron irradiation, have high readout rates,...
The current trend in X-ray radiotherapy is to treat cancers that are difficult locations the body using beams with a complex intensity profile. Intensity-modulated (IMRT) treatment which improves dose distribution tumor whilst reducing healthy tissue. Such treatments administer larger per fraction and hence require more methods verify accuracy of delivery. Measuring beam fluctuations as heavily distorted after leaving patient transmission detectors will attenuate change energy spectrum beam....
Abstract Higher energy and intensity X-ray radiotherapy treatments are coming into wider use, having the benefit of requiring fewer treatment fractions hospital visits per patient. However, small percentage errors in multileaf collimator positioning dose become bigger problems with higher doses fraction. Hence, real-time verification becomes essential. Where devices downstream from patient suffer scattering patient, upstream can disturb therapeutic beam. Here, a method is proposed for...
Intensity-modulated radiotherapy is a widely used technique for accurately targeting cancerous tumours in difficult locations using dynamically shaped beams. This ideally accompanied by real-time independent verification. Monolithic active pixel sensors are viable candidate providing upstream beam monitoring during treatment. We have already demonstrated that Active Pixel Sensor (MAPS)-based system can fulfill all clinical requirements except the minimum required size. Here, we report...
Abstract A multileaf collimator (MLC) is an integral component in modern radiotherapy machines as it dynamically shapes the photon field used for patient treatment. Currently, MLC leaves which collimate treatment are mechanically calibrated to ±1 mm every 3 months and during pre-treatment calibration set leaf positions. Leaf drift can occur between dates hence exceed tolerance. Pre-treatment verification, increases LINAC usage time so seldom performed each individual treatment, but instead...
Multileaf collimators (MLC) are an integral component in modern radiotherapy as they shape the X-ray treatment beam and therefore need to be closely controlled. Currently, MLC leaves calibrated ± 1 mm every month, however can drift beyond this during calibration dates verification only occurs pre-treatment. MAPS radiation hard photon electron irradiation, have high readout speeds low attenuation which makes them ideal upstream detector. Here, we report results using Lassena MAPS, is 12×14 cm...
Monolithic Active Pixel Sensor (MAPS) devices are an effective tool for upstream verification of Intensity Modulated Radio Therapy treatments. It is crucial to measure with high precision the positions Multi Leaf Collimators (MLC) used shape beam, in order enhance quality and safety This work describes a two-step procedure applied problems leaf detection position reconstruction. represents building block towards definition real-time device capable detecting reconstructing MLC everyday...
Abstract Intensity modulated radiotherapy is a widely used technique for accurately targeting cancerous tumours in difficult locations. As treatments are becoming more complex, new methods need to be developed monitor them. Monolithic active pixel sensors viable candidate providing upstream beam monitoring during treatment. A MAPS based system can made thin enough have less than 1% attenuation. We already demonstrated leaf position resolutions below 130µm at the iso-centre 5mm wide leaves...