A5036801744- CRISPR and Genetic Engineering
- Biomedical and Engineering Education
- Plant nutrient uptake and metabolism
- Plant-Microbe Interactions and Immunity
- Animal Vocal Communication and Behavior
- Plant Stress Responses and Tolerance
- Bat Biology and Ecology Studies
- Plant Pathogenic Bacteria Studies
- Genetically Modified Organisms Research
- Insect and Pesticide Research
- Plant Virus Research Studies
- Plant Molecular Biology Research
- Transgenic Plants and Applications
- SARS-CoV-2 and COVID-19 Research
- Wheat and Barley Genetics and Pathology
- Plant Parasitism and Resistance
- Avian ecology and behavior
- Bacillus and Francisella bacterial research
Engineering Biology Research Consortium
2021-2022
Molecular Biology Consortium
2021-2022
University of California, Berkeley
2013-2021
Significance Susceptibility (S) genes are plant that facilitate pathogen infection. Inactivation of S has been considered a promising strategy to obtain broad-spectrum and durable resistance in crops. We characterized two orthologs the Arabidopsis gene DMR6 tomato: SlDMR6-1 SlDMR6-2 . show SlDMR6-1, but not SlDMR6-2, is associated with immunity. Remarkably, Sldmr6-1 mutants display enhanced bacterial, oomycete, fungal pathogens. This phenotype correlates increased levels defense hormone...
Genetic engineering is a molecular biology technique that enables gene or genes to be inserted into plant's genome. The first genetically engineered plants were grown commercially in 1996, and the most common traits are herbicide insect resistance. Questions concerns have been raised about effects of these on environment human health, many which addressed pair 2008 2009 Annual Review Plant Biology articles. As new science published techniques like genome editing emerge, reanalysis some...
Engineering biology is being applied toward solving or mitigating some of the greatest challenges facing society. As with many other rapidly advancing technologies, development these powerful tools must be considered in context ethical uses for personal, societal, and/or environmental advancement. Researchers have a responsibility to consider diverse outcomes that may result from knowledge and innovation they contribute field. Together, we developed Statement Ethics Biology Research guide...
Summary Unidirectional, continuous airflow through the avian lung is achieved an elaborate air sac system with a sequential, posterior to anterior ventilation pattern. This classical model was established various approaches spanning passively ventilated systems mass spec analysis of tracer gas flow into sacs during spontaneous breathing in restrained ducks. Information on patterns other bird taxa missing, and these techniques do not permit direct tests whether basic pattern can change...
The ability to construct, synthesize, and edit genes genomes at scale with speed enables, in synergy other tools of engineering biology, breakthrough applications far-reaching implications for society. As SARS-CoV-2 spread around the world early spring 2020, researchers rapidly mobilized, using these development diagnostics, therapeutics, vaccines COVID-19. sharing knowledge was crucial making rapid progress. Several publications described use reverse genetics de novo construction...
A large-scale agroterrorism attack on the United States would likely have severe economic and social consequences. In particular, destruction of crops with pests or pathogens could cause substantial damage to food, economic, stability, relatively little health risk perpetrators. The tools engineering biology enable a well-trained, nefarious actor amplify their desired impacts through development disease-intensifying traits. States, plant emergencies are handled first at local state levels,...