- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Pharmacological Effects and Toxicity Studies
- Neonatal and fetal brain pathology
- Sympathectomy and Hyperhidrosis Treatments
- Intracranial Aneurysms: Treatment and Complications
- Long-Term Effects of COVID-19
- Neuroscience and Neuropharmacology Research
- Diet and metabolism studies
- Cerebrovascular and Carotid Artery Diseases
- Fetal and Pediatric Neurological Disorders
- Moyamoya disease diagnosis and treatment
- Neurological Complications and Syndromes
- Neurological disorders and treatments
- Sexual function and dysfunction studies
- Migraine and Headache Studies
- Vascular Malformations Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Ophthalmology and Eye Disorders
- Urinary Bladder and Prostate Research
- Peroxisome Proliferator-Activated Receptors
- Meningioma and schwannoma management
- Nitric Oxide and Endothelin Effects
- Hemoglobinopathies and Related Disorders
- Cardiovascular Health and Disease Prevention
Medanta The Medicity
2018-2024
Pain Clinic of India
2023
Medanta The Medicity
2014-2021
Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals
2020
B. J. Medical College & Sassoon Hospital
2020
Sree Chitra Thirunal Institute for Medical Sciences and Technology
2009-2010
With increasing knowledge of the coronavirus disease-2019 (COVID-19), we now understand that COVID-19 presents with various extrapulmonary manifestations multi-organ involvement. Involvement central nervous system (CNS) occurs probably via transsynaptic spread or transfer across blood-brain barrier. Hypoxia, immune-mediated injury, and vascular damage are potential mechanisms for CNS manifestations. Headache, dizziness, chemosensory disturbances, such as loss smell, taste, encephalopathy,...
Abstract Neuropsychology plays an important role in optimizing epilepsy management, but there are no practice guidelines for low‐ and middle‐income countries with emerging services. The National Epilepsy Surgery Support Activity Network (NESSAN), a national working group that supports optimizes surgery programs India, explored the present status of pre‐ post neuropsychological assessment practices across India as initial step developing evidence‐based test guidelines. An online survey was...
Eating epilepsy is a rare form of reflex where seizures are triggered by eating.We describe case series 12 such patients presenting to our clinic based in North India.Eating was noted have male predominance with focal impaired awareness.Most these had either temporal or perisylvian localization.Clobazam taken half an hour before meal found be effective add-on therapy its management.
We, as neurologists, are frequently consulted to give neurological clearance for surgery in patients who undergoing coronary artery bypass graft (CABG) and have suffered from stroke or transient ischemic attack (TIA) past. Similarly is also sought another group of who, though not TIA, but found significant carotid stenosis on routine screening prior surgery. Cardiac surgeons anesthetists want know the risk perioperative such should endarterectomy (CEA) be done along with CABG. In absence any...
Posterior reversible encephalopathy syndrome (PRES) is a clinical radiographic diagnosis of heterogeneous etiologies. The pathogenesis PRES remains unclear, but may be related to impaired cerebral autoregulation and endothelial dysfunction. We present case intravascular nonionic contrast-induced observed after angiography. index patient was follow-up large vertebrobasilar artery-dissecting aneurysm for which endovascular coiling done 6 months back. She improved completely within week....
Abstract Benign epileptiform variants (BEVs) are often noted in routine electroencephalogram (EEG) monitoring and sometimes misinterpreted as discharges. Six 14 Hz positive spikes one of such BEVs seen especially children. However, these can also be intensive care unit EEG recordings. Here, we have reviewed the history electrical details 6 with their clinical significance.
Valproic acid (VPA) is a well established anticonvulsant drug for the last 40 years and now part of more than 130 national health care programmes. Since 1988, it has regularly featured as an in WHO Model List Essential Medicines [[1]]. The current NICE Guidelines recommend Acid first-line treatment Idiopathic Generalized Epilepsies (IGEs) children, young people adults but should be used with caution pregnant women. [[2]]
A 17-year-old boy presented with left focal seizures and progressive hemiparesis for 10 years.Serial MRIs showed right cerebral contralateral cerebellar atrophy (figure).He is seizure-free after hemispherotomy.Pathology was compatible Rasmussen encephalitis.Crossed diaschisis subsequent crossed atrophy, due to supratentorial lesions or chronic seizures, represents the best evidence of transneuronal depression in humans. 1 Contrary original concept reversible dysfunction diaschisis, 2 distant...
Abstract We present an interesting EEG finding of persistent unilateral sweat artifacts in a 47 years old male patient with right hemiplegia secondary to left thalamic bleed extension hemorrhage into the internal capsule, midbrain and ventricles. The was done for altered sensorium. It showed (right sided) throughout recording. anhydrosis on side face due sided Horner's syndrome because involvement first order neurons midbrain. This is highlighted it being relatively less common but finding.
Abstract Transient ischemic attack (TIA) is defined as a temporary focal neurological deficit of presumed vascular origin, lasting for less than 1 h, with no evidence infarct on neuroimaging. If patient suffering from multiple cardiovascular risk factors and presents transient recurrent deficits, the most likely diagnosis considered TIA. As possibility stroke within first 24 h high, such patients need aggressive investigation management, ideally should be hospitalized. TIA usually occurs due...
Landau-Kleffner syndrome (LKS) is described by the International Classification of Epileptic Syndromes since 1985 as a constellation clinical and electrographic signs, including acquired aphasia, regression language milestones seizures, along with sleep-activated paroxysms on electroencephalogram which can progress to status epilepticus sleep. In this case, 7-year-old boy presented an atypical history new-onset aphasia rare seizures. However, there was mismatch in form right-sided...
A 7-year-old boy presented with acute onset headache, vomiting, and visual deterioration 2 weeks previously without any cognitive or behavioral changes.Optic fundi showed papilledema, there were no pyramidal signs gait disturbances.The remainder of the neurologic examination was normal.CSF protein 174 mg/dL.Although MRI features (figure) consistent adrenoleukodystrophy (ALD), atypical presentation prompted consideration alternate diagnoses therapies.Subsequent progressive vision hearing...
We are reporting a case of rare reflex epilepsy—“startle” epilepsy effectively treated with hemispherotomy. A 6-year-old boy, child nonconsanguineous parentage infantile hemiparesis presented to us recurrent right focal seizures along secondary generalization provoked by sudden and unexpected auditory stimuli for the last 1 year. The boy had minimum four episodes per day despite maximal medical management multiple antiepileptic drugs. Magnetic resonance imaging brain showed severe atrophy...
Q.9. A 35-year obese female is having migraine and primary generalised epilepsy. Which anti-epileptic you will prefer
Abstract Supraorbital neuralgia is a severe, painful, difficult-to-treat condition that often misdiagnosed. It characterized by pain and tenderness in the region of supraorbital notch forehead, with transient relief nerve block. resistant to pharmaceutical treatment, so non-pharmaceutical management preferred option, but it comes side effects. However, newer treatment modalities such as cryoneurolysis are safe options due their reversible second-degree injury peripheral sensory no effect on...
Background: Migraine limb pain is a very under-recognized manifestation of migraine in which episodic happens the peripheral limbs. Despite its description for many years, only limited clinical details are known. Only case reports and series with as symptom reported literature. In this report, important features unilateral it’s association has been discussed. Case presentation: Here author (a neurologist) describes from his own experience, started childhood used to be episodic, changing...