A5073895822- Neonatal Respiratory Health Research
- Infant Development and Preterm Care
- Antibiotic Resistance in Bacteria
- Neuroscience of respiration and sleep
- Global Maternal and Child Health
- Infant Nutrition and Health
- Infections and bacterial resistance
- Energy and Environment Impacts
- Pregnancy and preeclampsia studies
- HIV-related health complications and treatments
- HIV/AIDS Research and Interventions
- Maternal and Perinatal Health Interventions
- Antioxidant Activity and Oxidative Stress
- Infant Health and Development
- Pneumocystis jirovecii pneumonia detection and treatment
- vaccines and immunoinformatics approaches
- Pregnancy and Medication Impact
- Immune responses and vaccinations
- Immunodeficiency and Autoimmune Disorders
- Breastfeeding Practices and Influences
- Biomedical Research and Pathophysiology
- Urinary Tract Infections Management
- Maternal and fetal healthcare
- Emergency and Acute Care Studies
- Gestational Diabetes Research and Management
University of Abuja Teaching Hospital
2011-2025
University of Abuja
2010-2025
Imperial College London
2022
University of Maiduguri
2022
World Health Organization
2021
Bloomberg (United States)
2020
Bangabandhu Sheikh Mujib Medical University
2020
The safety and efficacy of antenatal glucocorticoids in women low-resource countries who are at risk for preterm birth uncertain.
Infections caused by multi-drug resistant Enterobacterales (MDR-E) are difficult to treat and cause significant mortality, especially in developing countries. This study characterized the phenotypic genotypic profiles of 49 randomly selected beta-lactam MDR-E previously isolated from patients being managed hospitals Nigeria using whole genome sequencing. The isolates exhibited 85.5% resistance 3rd generation cephalosporins 65.3% carbapenems. blaTEM-1B (29, 59.2%), blaCTX-M-15 (38, 77.6%),...
Background.Etiologic agents of childhood bacteremia remain poorly defined in Nigeria.The absence such data promotes indiscriminate use antibiotics and delays implementation appropriate preventive strategies.Methods.We established diagnostic laboratories for surveillance at regional sites central northwest Nigeria.Acutely ill children aged <5 years with clinically suspected were evaluated rural urban clinical facilities the Federal Capital Territory, region Kano, Nigeria.Blood was cultured...
Respiratory distress is a common presenting clinical sign in newborn infants. It manifestation of several underlying conditions including congenital pneumonia, respiratory syndrome, sepsis, perinatal asphyxia etc; however, if not properly managed with good support device it could lead to an unfavourable outcome. Aim: Preliminary report on effectiveness Politeheart CPAP the care neonatal distress. Methods: The initial phase involved training end-users principles and techniques new device....
Highlights•High measles risk in newborns across six African and three South Asian countries.•Predicted loss of immunity all infants by months age.•The current recommended vaccine schedules warrant reconsideration.AbstractObjectivesTo investigate the transplacental acquisition IgG newborn at delivery Bangladesh, Bhutan, India, Ethiopia, Mozambique, Kenya, Nigeria, Mali, Africa.MethodsArchived cord serum, from a multi-center study on Group B Streptococcus, were tested for using commercial...
Background: The bubble continuous positive airway pressure (bCPAP) technique is widely applied in neonatal respiratory support. Commercial bCPAP brands are expensive Nigeria and this has driven Nigerian paediatricians to use potentially risky improvised devices (IbCPAP). Aim: This study aimed design, produce trial an appropriate low-cost machine which functionally effective safe. Methods: Questionnaires were distributed assess the need for a new design Nigeria, leading development of system...
Over 70% of neonatal deaths in Nigeria occur within the first 7 days life and, despite millennium development goals, there has been no significant reduction this figure.To investigate how rapid changes temperature outside physiologically allowable range extremely low-birthweight infants are associated with increased mortality.Ninety-eight cases three Nigerian tertiary-care hospitals were retrospectively recruited; on basis birthweight < 1500 g, number was reduced to 41 for a two-stage...
Oxidative stress is associated with adverse pregnancy outcomes, and vitamin E has powerful anti-oxidant properties the potential to impact health outcomes. Tocopherol isomers of differ in their ability modulate inflammation vary concentration diets containing high proportions processed versus unprocessed foods. The purpose this study was compare status outcomes (mode delivery, chorioamnionitis, APGARs (measure appearance, pulse, grimace, activity, respiration), gestational age at fetal...
Nigeria has a record of high newborn mortality as an estimated 778 babies die daily, accounting for ratio 48 deaths per 1000 live births. The aim this paper was to show how deteriorating neonatal delivery system in may have, part, been improved by the application novel recycled incubator technique (RIT). Retrospective assessment clinical, technical, and human factors 15 Nigerian centres carried out investigate RIT impacted these factors. Pre-RIT post-RIT mortalities were compared studying...
Background: In Nigeria, neonatal jaundice is commonly treated by overhead phototherapy with neonates lying supine, often effective exposure of less than one half the body surface. Total in has been use for 2 years but available only five centres.Aim: To compare effectiveness total (TBPE) conventional partial (COPT) treatment hyperbilirubinaemia.Methods: Eleven datasets from 10 units across Nigeria were retrieved. They included severe hyperbilirubinaemia TBPE using Firefly® device (MTTS Asia)...
Abstract Objective To describe the outcomes and quality of care for women their babies after caesarean section (CS) in Nigerian referral‐level hospitals. Design Secondary analysis a nationwide cross‐sectional study. Setting Fifty‐four Population All giving birth participating facilities between 1 September 2019 31 August 2020. Methods Data were extracted, including sociodemographic data, clinical information, mode birth, maternal perinatal outcomes. A conceptual hierarchical framework was...
Low levels of vitamin D in maternal and cord blood have been associated with neonatal sepsis. This study assessed the association metabolites (25(OH)D, 3-epi-25(OH)D3, 24,25(OH)2D3) newborn sepsis evaluation Nigerian mother–infant dyads. Maternal from 534 mothers 536 newborns were processed using liquid chromatography-tandem mass spectrometry. Spearman correlation was used to compare continuous variables, Mann–Whitney for dichotomous Kruskal–Wallis two or more groups. High percent...
Introduction: Highest proportion of most vulnerable Nigeria neonates are concentrated in hard-to-reach local villages without proper intervention devices owing to unavailable electric power. Hence, majority needy continue lose their lives due inability journey urban cities where few inadequately equipped neonatal centres located. The Nigerian healthcare system requires the make often-treacherous journeys, travelling into search possible intervention. This has continued fail generations...
Objectives: To evaluate immunologic response to antiretroviral treatment (ART) among HIV-infected Nigerian children (<36 months old) and assess its association with early infant feeding pattern nutritional status at initiation. Design: Mixed prospective retrospective cohort study. Methods: One hundred fifty were followed for 12 from initiation of ART. CD4 count/CD4% was assessed baseline every 4–6 months. Nutritional by height-for-age, weight-for-age weight-for-height Z scores using the 2006...
( N Engl J Med . 2020;383:2514–2525) Antenatal glucocorticoids are a common intervention in preventing adverse outcomes associated with preterm birth. The evidence supporting this is based on trials high-resource settings, however, and 2015 trial low-resource countries found scaling up caused an increase neonatal death, stillbirth suspected maternal infection. World Health Organization (WHO) has issued guidelines restricting the use of antenatal to certain situations. This study, WHO...
Background: Neonatal resuscitation is a method of preventing morbidities & mortality from asphyxia. Up to 85% facilities in sub-Saharan Africa lack supplies or skilled personnel for neonatal resuscitation. Relative the place birth and skill attendant, variety resuscitative practice are employed make babies cry instead helping baby breathe. Many painful procedures applied when unable after absence health care worker trained bag-mask ventilation.Objectives: To ascertain practices communities...
Introduction: The organism Sphingomonas paucimobilis formerly known as Pseudomonas is a strict aerobe, motile, non-spore forming, non-fermentative, Gram-negative bacillus, characterized by catalase and oxidase activities. It an opportunistic pathogen that causes infection in healthy immunocompromised individuals. ubiquitous has been isolated from diverse sources including the hospital environment.
 Presentation of Case: We describe clinical characteristics, manifestations, laboratory...
Background and Aims: Intraventricular hemorrhage (IVH) is a major complication of preterm birth large haemorrhages may yield significant future disability. Although multifactorial, prematurity low weight are the most important risk factors for IVH. Furthermore, being “born too soon” affects accretion Vitamin A (VA) which essential normal brain development. We sought out to estimate VA nutrient levels among newborn infants at establish any relationship with IVH occurrence grade severity....
The study objective was to evaluate the association between early infant feeding, nutritional status and growth of HIV-infected children on ART in a resource-poor setting. comprised 150 followed for 12 months from initiation. Outcomes were at treatment initiation, over months, 12-month assessed by HAZ, WAZ WHZ using WHO reference. Children classified into 3 groups - exclusively breast or formula fed (EBFF), predominantly breastfed (PBF) mixed (MF). Early feeding pattern significantly...