A5033866948- Acute Myeloid Leukemia Research
- Cardiac, Anesthesia and Surgical Outcomes
- Management of metastatic bone disease
- Bone health and treatments
- Acute Lymphoblastic Leukemia research
- Gastrointestinal disorders and treatments
- Enhanced Recovery After Surgery
- Histone Deacetylase Inhibitors Research
- Healthcare Systems and Public Health
- Oral and Maxillofacial Pathology
- Fetal and Pediatric Neurological Disorders
- Orthopaedic implants and arthroplasty
- Cancer Diagnosis and Treatment
- Renal and related cancers
- Medical and Biological Sciences
- Bone Tumor Diagnosis and Treatments
- Sarcoma Diagnosis and Treatment
- Lymphatic System and Diseases
- Bariatric Surgery and Outcomes
- Anatomy and Medical Technology
- Anorectal Disease Treatments and Outcomes
- Chronic Lymphocytic Leukemia Research
- Retinopathy of Prematurity Studies
- Apelin-related biomedical research
- Sympathectomy and Hyperhidrosis Treatments
Sechenov University
2025
National Medical Research Center of Cardiology
2025
Moscow State University
2020
Lomonosov Moscow State University
2020
Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan
2019
Kazan State Medical University
2019
Polyclinic General Hospital
2019
Samara State Medical University
2017-2018
Russian Academy of Sciences
2017
Russian Children's Clinical Hospital
2012
Introduction Cholesteatomas of the clivus and pyramids temporal bone can significantly reduce quality life patients due to damage cranial nerves. The only effective method for their treatment is surgery. Materials methods study included a case series eight patients: five females three males. In all cases, lesions were located within pyramid bone. All operations performed using an endoscopic transnasal approach. Results underwent successful surgical treatment. Near-total removal (95%-99%...
Background. Acute myeloblastic leukemia (AML) with NPM7 mutation amounts to 30 % of all AML and is characterized by good prognosis the exception cases FLT3-/TD mutation. Despite prognosis, likelihood relapses in patients may significantly differ. Thus, estimation minimal residual disease (MRD) after chemotherapy during follow-up becoming increasingly important. This approach will make it possible predict sensitivity a tumoral clone chemotherapy. Aim. To evaluate prognostic value highly...
Rationale. The article presents the data obtained by an improved method of contrast-enhanced ultrasound (CEUS) in patients with chronic viral hepatitis.
 Methods. We compared quantitative and qualitative CEUS parameters 2 groups patients: 1st group was administered 2.5 ml contrast agent, 2nd 1.0 agent.
 Results. results showed that had no statistical differences arterial portal phases.
 Conclusion. late venous phase were not clinically significant, since study objective...
Background. The current approach to treatment of acute myeloblastic leukemia (AML) includes the achievement maximum tumor reduction and, therefore, eradication a leukemic clone. goal therapy is achieve undetectable levels target gene, except an isolated molecular rearrangement RUNX1-RUNX1T1. Aim. To estimate dynamics RUNX1-RUNX1T1 level and relevant clinical manifestations during monitoring various stages program after its completion. Methods. article presents description 10 cases AML with...
Aim - to evaluate the proliferative activity of dermal fibroblast cultures in presence composite materials based on titanium silicides vitro. Materials and methods. To assess fibroblasts vitro, following were used: silicide, carbosilicide oxidized vacuum without vacuum, VT-00 (comparison group). Testing was carried out by direct contact method. The proliferation index, doubling time number culture during cultivation period calculated. Attachment surface test their it assessed scanning...
The article presents an original method for personalized predicting surgical outcomes in patients with tumors of diencephalic and suprasellar localization based on a clinical epidemiological approach the use intelligent analysis (Data Mining) electroencephalo-graphic data. Use methods allowed us to programmatically select nosologically specific test making outcome prognosis, including sensitivity specificity calculations.
Acute myeloid leukemias (AML) are the most ubiquitous of all adult leukemias. The prognosis disease depends on its genetic profile. mutation in FLT3 gene, which codes FMS-like tyrosine kinase 3, is observed 1/3 patients and responsible for a high rate relapses. relapsed/refractory FLT3-positive AML extremely poor. standard intensive therapy rarely yields long-term responses. new first- second-generation inhibitors enriched treatment opportunities with this mutation. Gilteritinib, potent...
The aim of the investigation was to evaluate possibilities applying 3D modeling and computer navigation in treatment benign tumors tumor-like diseases tubular bones.Materials Methods.The study involved 19 patients with bones skeleton, who were divided into two groups.The main group comprised 10 whom three-dimensional models affected bone segments created addition radiography computed tomography at stage preoperative planning.Surgical carried out using a system.The control included 9...
Aim - to analyze the results of use 3D modeling and computer navigation in treatment benign tumors tumor-like diseases long bones. Materials methods. The study included 19 patients with diseases. main group consisted 10 patients. In preoperative planning stage, addition X-ray computed tomography these had 3D-models affected bone segment constructed. Surgical was carried out system. control 9 who underwent radiography stage. Results. application new method made possible reduce operation time...
AIM: to estimate efficacy of local use fluocortolone pivalate combined with lidocaine for postoperative pain after excisional hemorrhoidectomy. PATIENTS AND METHODS: two-hundred patients were included in retrospective study. All underwent Patients divided two groups, each group 100 comparable demographics, hemorrhoids stage. Traditional systemic relief was used both groups and NSAIDs opioid receptor antagonists. The main additional combination operative theatre, every day during control...
In the given research from point of system analyses is studied haemodynamicy as an integral and one most leading factors affecting safety operating period by invasions under circumstances carboxyperitoneum patients with heart problems. It shown that similar nosological forms combine heterogenic patients' groups different reactions for surgical stress. Obese have a more impressive move vegetative homeosthasis to side symphaticothony centralization rhythmus ruling, sharp decrease adaptational...
Traumas and diseases of the musculoskeletal system are second among causes temporary disability population, third mortality. An effective method treatment is endoprosthetics. ; Every year across globe 500-1000 patients per 1 million population require prosthetics. The development endoprostheses progressing in various spheres: design implant parts, methods fixation, use materials, different types surface finish implants. Endoprostheses that currently produced used traumatology orthopaedics...
Aim. To assess the efficacy of FLAG/FLAG-Ida regimen and to identify factors that influence remission, duration disease-free survival (DFS) overall (OS) patients with relapsed/refractory acute myeloid leukemia (AML). Materials & Methods. The trial included 54 (28 men 26 women), median age was 37 years (range 18-70 years). 27 (50 %) out had refractory AML relapsed AML. FLAG FLAG-Ida regimens were administered as induction therapy. (68.5 received bone marrow transplantation. Molecular...
The treatment of refractory acute myeloid leukemia (AML) patients presents considerable challenges. They are often critically ill. critical conditions these mainly associated with severe infectious complications resulting in sepsis as well the extramedullary lesions organ dysfunctions. So far, obtained data demonstrated successful use gemtuzumab ozogamicin, mechanism which is likely to be based not only on depletion CD33-positive tumor cells but also its immunomodulatory effect. present...
The material of this work presents the problem surgical treatment patients with severe obesity. assessment methods applied by authors in combined bariatric operations is given on oun material.
In the preformed research is studied economical efficiency and social significance of simultaneous operative invasions in surgery gynecology. It shown that rational usage miniinvasion technologies leads to decreasing stationary hospital period patients summary his disability here are also reduced expenses per day patient's insureness, for postoperative observations narcosis. very actual treatment with different obesity degrees. By way there made circumstances more operating expensive...
Isolated mild cerebral ventriculomegaly (IVM) is difficult to prognosis condition. We have used MR imaging & sonography as an aid in prenatal counseling since 2000. In the period 2000–2011 was found by ultrasound 96 cases of IVM. Fetal IVM detected a ventricular atrial width 10.0–12.0 mm, without congenital malformations (CM) and other chromosomal abnormalities (CA) echographic markers (EM). All scans are carried out sonographer having experience genetic expert on cardiovascular ultrasound....