A5055855109- Photoacoustic and Ultrasonic Imaging
- Surface Modification and Superhydrophobicity
- Nanoplatforms for cancer theranostics
- Adhesion, Friction, and Surface Interactions
- Carbon Nanotubes in Composites
- Photodynamic Therapy Research Studies
- Polymer Surface Interaction Studies
- Optical Imaging and Spectroscopy Techniques
- Polymer Nanocomposites and Properties
- Extracellular vesicles in disease
- Chinese history and philosophy
- Hepatocellular Carcinoma Treatment and Prognosis
- Pickering emulsions and particle stabilization
- Adipose Tissue and Metabolism
- Advanced Polymer Synthesis and Characterization
- Silicone and Siloxane Chemistry
- Icing and De-icing Technologies
- Advanced Computational Techniques and Applications
- Digital Media and Visual Art
- Surfactants and Colloidal Systems
- Cardiovascular Disease and Adiposity
- Advanced Sensor and Energy Harvesting Materials
- Ideological and Political Education
- Polymer crystallization and properties
- Aerosol Filtration and Electrostatic Precipitation
University of Massachusetts Lowell
2016-2025
Institute of Advanced Science Facilities, Shenzhen
2024
Guangdong Medical College
2024
Xiamen University
2019-2023
China Pharmaceutical University
2023
China Institute of Geological Environmental Monitoring
2004-2022
Guangdong Provincial People's Hospital
2022
Guangdong Academy of Medical Sciences
2022
Ministry of Education of the People's Republic of China
2022
Ministry of Natural Resources
2022
Ischemic stroke (IS) is one of the leading causes death and accounts for 85% cases.Since symptoms are not obvious, diagnosis IS, particularly at an early stage, a great challenge.Photoacoustic imaging combines high sensitivity optical fine resolution ultrasonography to non-invasively provide structural functional information IS.Methods: We adopted three rapid photoacoustic systems with varying characteristics, including portable handheld system, high-sensitivity bowl-shaped array computed...
Simultaneous spatio-temporal description of tumor microvasculature, blood-brain barrier, and immune activity is pivotal to understanding the evolution mechanisms highly aggressive glioblastoma, one most common primary brain tumors in adults. However, existing intravital imaging modalities are still difficult achieve it step. Here, we present a dual-scale multi-wavelength photoacoustic approach cooperative with/without unique optical dyes overcome this dilemma. Label-free depicted multiple...
Superhydrophobic coatings are beneficial for applications like self-cleaning, anti-corrosion, and drag reduction. In this study, we investigated the impact of surface geometry on static, dynamic, sliding contact angles in Cassie–Baxter state. We used fluoro-silane-treated silicon micro-post patterns fabricated via lithography as model surfaces. By varying solid fraction (ϕs), edge-to-edge spacing (L), shape arrangement micro-posts, examined how these geometric factors influence wetting...
Production–living–ecological space (PLES) is the main body of optimization development and protection pattern territorial space, spatial conflict in PLES reflects a struggle for ecological socio-economic process utilization. The Yellow River Basin one most concentrated prominent areas China. Therefore, clarifying spatio-temporal region scientifically identifying characteristics its will significantly improve efficiency comprehensive utilization resources, promote integrated orderly resource...
Macroporous magnetic poly(styrene–divinylbenzene) [P(St–DVB)] nanocomposites with an open-cell structure have been synthesized through high internal phase emulsion (HIPE) templates solely stabilized by surface-modified magnetite nanoparticles (MPs). When the particle concentration was below 20% based on monomers, compression strength increased increasing of particles, while average void size became small and distribution voids tended to be narrow. On other hand, mechanical properties...
Nanoparticle-based photothermal ablation (PTA) has been intensively investigated recently. However, the poor biocompatibility of most PTA agents and potential long-term toxicity obstruct their clinical translation. Meanwhile, previous studies are limited to surface tumors because insufficient light penetration depth near-infrared (NIR) for deep abdominal tumors. Therefore, minimally invasive combined with biocompatible may pave a promising way treat orthotopic hepatocellular carcinoma (HCC)....
In this work, the drag reduction (DR) performance of superhydrophobic composite coatings was investigated. The DR behavior for both short-term and long-term use studied using a parallel-plate rheometer, morphology interface by fluorescence staining. For performance, increased with higher silica NP content in composition up to 40% weight. played governing role except very high particle loading sample. surface topography effect on also studied. increase autocorrelation length found be related...
Nanobubbles (NBs) have recently gained interest in cancer imaging and therapy due to the fact that nanoparticles with size range of 1–1000 nm can extravasate into permeable tumor types through enhanced permeability retention (EPR) effect. However, therapeutic study NBs was only limited drug delivery or cavitation. Herein, we developed ultrasound-evoked massive NB explosion strikingly damage surrounding cancer. The dual-function agent allows synergistic mechanical impact photodynamic tumors...
Epoxy nanocomposites are widely used in various applications because of their excellent properties. Different types manufacturing techniques to produce epoxy composites based on fillers, molecular weight, and required. The physical properties chemical structure resin help determining the method for its manufacturing. Coatings adhesive formulations prepared using high- molecular-weight epoxies, whereas require low-molecular-weight epoxies due ease A can provide high crosslink density but may...
Synchrotron radiation light source has been successfully used in material science, biomedicine, and other fields because of its high intensity, good monochromaticity, excellent coherence collimation. In recent years, the significantly expedited advancement medical applications. High contrast spatial-temporal resolution images based on synchrotron X-ray have obtained, presenting innovative opportunities for precise clinical diagnosis therapy. this review, we first delineate characteristics...
A novel approach for synthesizing polymer particles that encapsulate Fe3O4 nanoparticles using γ-ray irradiated mini-emulsion polymerization is presented. To achieve high encapsulation efficiency, the surface properties of are modified from hydrophilic to hydrophobic, allowing effective dispersion in monomer prior polymerization. Mini-emulsion techniques have proven essential forming encapsulated structure and controlling particle size distribution. irradiation initiated radical solidified...
Carbon nanotube (CNT) polymer composites are widely used as raw materials in multiple industries because of their excellent properties. This expansion, however, is accompanied by realistic concerns over potential release CNTs and associated nanoparticles during the manufacturing, recycling, use, disposal CNT composite products. Such data continue to be limited, especially with regards post-processing CNT-enabled products, recycling handling nanowaste, end-of-life disposal. study investigated...
Accurate diagnoses of superficial and deep dermal burns are difficult to make even by experienced investigators due slight differences in dermis damage. Many imaging technologies have been developed improve the burn depth assessment. But these tools limitations or resolving ability. Photoacoustic is a hybrid modality combining optical ultrasound that remains high resolution depth. In this work, we used dual-scale photoacoustic noninvasively diagnose injury monitor healing. Real-time PACT...
With production of nanocomposites, the product life cycle, including recycling, becomes critical.
In this study, particle loading, polyfluorinated alkyl silanes (PFAS or FAS) content, superhydrophobicity, and crack formation for nanocomposite coatings created by the spray coating process were investigated. The formulations comprised hydrophobic silica, epoxy resin, fluorine-free FAS constituents. effect of content FAS-free compositions on silica coatings’ chemistry, topography, wetting properties was also studied. All higher loadings (~30 wt.%) showed while lower loading did not show...
Enhanced photoacoustic performance and therapeutic outcomes of melanin-based organic agents for dual-modality imaging photothermal ablation orthotopic hepatocellular carcinoma.
The effect of particle loading on the wetting properties coatings was investigated by modifying a coating formulation based hydrophilic silica nanoparticles and poly (acrylic acid) (PAA). Water contact angle (WCA) measurements were conducted for all to characterize surface properties. Wettability improved with an increase in loading. resulting showed superhydrophilic (SH) behavior when above 53 vol. %. No new peaks detected attenuated total reflection (ATR-FTIR). topography studied atomic...
Cerebral ischemia-reperfusion injury (CIRI) is a major challenge to neuronal survival in acute ischemic stroke (AIS). However, effective neuroprotective agents remain be developed for the treatment of CIRI. In this work, we have an Anti-TRAIL protein-modified and indocyanine green (ICG)-responsive nanoagent (Anti-TRAIL-ICG) target areas then reduce CIRI rescue penumbra. vitro vivo experiments demonstrated that carrier-free can enhance drug transport across blood-brain barrier (BBB) mice,...
Superhydrophilic coatings based on a hydrophilic silica nanoparticle suspension and Poly (acrylic acid) (PAA) were prepared by dip coating. Scanning Electron Microscopy (SEM) Atomic Force (AFM) used to examine the morphology of The effect surface dynamic wetting behavior superhydrophilic was studied changing concentration from 0.5% wt. 3.2% while keeping in dry coating constant. droplet base diameter contact angle with respect time measured using high-speed camera. A power law found describe...
Protein fouling on critical biointerfaces causes significant public health and clinical ramifications. Multiple strategies, including superhydrophobic (SHP) surfaces coatings, have been explored to mitigate protein adsorption solid surfaces. SHP materials with underwater air plastron (AP) layers hold great promise by physically reducing the contact area between a substrate molecules. However, sustaining AP stability or lifetime is crucial in determining durability long-term applications of...